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UNC-authored articles published by Frontiers
Works (762)
91. Estimating the effects of COVID-19 on essential health services utilization in Uganda and Bangladesh using data from routine health information systems
- Title Tesim:
- Estimating the effects of COVID-19 on essential health services utilization in Uganda and Bangladesh using data from routine health information systems
- Creator:
- Rakib, Nibras Ar, Angeles, Gustavo, Kibria, Mohammad Golam, Ahsan, Karar Zunaid, Weiss, William, Mpiima, Jamiru, Silverstein, Hannah, Escudero, Gabriela, Singh, Kavita, and Simmons, Elizabeth
- Date of publication:
- 2023
- Abstract Tesim:
- Background Since March 2020, the coronavirus disease 2019 (COVID-19) pandemic has been a major shock to health systems across the world. We examined national usage patterns for selected basic, essential health services, before and during the COVID-19 pandemic in Uganda and Bangladesh, to determine whether COVID-19 affected reporting of service utilization and the use of health services in each country. Methods We used routine health information system data since January 2017 to analyze reporting and service utilization patterns for a variety of health services. Using time series models to replicate pre-COVID-19 trajectories over time we estimated what levels would have been observed if COVID-19 had not occurred during the pandemic months, starting in March 2020. The difference between the observed and predicted levels is the COVID-19 effect on health services. Results The time trend models for Uganda and Bangladesh closely replicated the levels and trajectories of service utilization during the 38 months prior to the COVID-19 pandemic. Our results indicate that COVID-19 had severe effects across all services, particularly during the first months of the pandemic, but COVID-19 impacts on health services and subsequent recovery varied by service type. In general, recovery to expected levels was slow and incomplete across the most affected services. Conclusion Our analytical approach based on national information system data could be very useful as a form of surveillance for health services disruptions from any cause leading to rapid responses from health service managers and policymakers.
- Resource type:
- Article
- Affiliation Label Tesim:
- Gillings School of Global Public Health, Department of Maternal and Child Health, Public Health Leadership Program, and Carolina Population Center
- DOI:
- https://doi.org/10.17615/w73p-zx77
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/fpubh.2023.1129581
- ISSN:
- 2296-2565
- Journal Title:
- Frontiers in Public Health
- Journal Volume:
- 11
- Keyword:
- SARS-CoV-2, routine health information system, time series model, maternal and child health, coronavirus disease 2019 (COVID-19), and health services use
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- , Johns Hopkins University, and Last Mile Health–Uganda
- Person:
- Rakib, Nibras Ar, Angeles, Gustavo, Kibria, Mohammad Golam, Ahsan, Karar Zunaid, Weiss, William, Mpiima, Jamiru, Silverstein, Hannah, Escudero, Gabriela, Singh, Kavita, and Simmons, Elizabeth
- Publisher:
- Frontiers Media SA
- Source:
- 1579dfb2-d623-445b-afcb-23abd1854985
92. Editorial: Vagus nerve-mediated drive in supporting homeostasis: optimizing global health through monitoring and stimulating vagal function
- Title Tesim:
- Editorial: Vagus nerve-mediated drive in supporting homeostasis: optimizing global health through monitoring and stimulating vagal function
- Creator:
- Niezgoda A., Rangon C.M., Porges S.W., and Moyse E.
- Date of publication:
- 2023
- Abstract Tesim:
- Epigenetics encompasses the changes in gene expression triggered by environmental cues that occur without altering the underlying DNA sequences. Although epigenetics involves a limited number of identified mechanisms so far (DNA methylation, histone modifications and noncoding RNAs), the field of Epigenetics is spreading rapidly over integrated physiopathology (Jeffries, 2020). The importance of epigenetics has been acknowledged in cancer (Sun et al., 2022), sepsis (Binnie et al., 2020), autoimmune/inflammatory diseases (Surace and Hedrich, 2019), addiction (Hamilton and Nestler, 2019), aging (Pal and Tyler, 2016; Pérez et al., 2022), neurodegenerative diseases (Berson et al., 2018; Zhang et al., 2022) and even in neurodevelopmental (Esposito et al., 2018; Wu et al., 2020) and psychiatric diseases (Abdolmaleky et al., 2023). Likewise, a broad and expanding set of therapies in clinics have been potentialized by tuning the vagal complex of brainstem, i.e., the key neural node of homeostasis, via non-invasive Vagus Nerve Stimulation (VNS) (Hilz, 2022). Moreover, Heart Rate Variability (HRV), a physiologically validated and easily accessible read-out of the vagal tone (Lewis et al., 2012), is acknowledged as a polyvalent prognostic tool (Gidron et al., 2018; Mol et al., 2021). This is not surprising, since Epigenome is considered as a “mediator for host-microbiome crosstalk” (Peery et al., 2021) and since vagus nerve represents the fastest pathway of the Microbiota-Gut-brain Axis (Fülling et al., 2019). However, except for regulating neuro-inflammation (Chen et al., 2022), the mechanisms through which VNS influences peripheral and central nervous system plasticity are not well described yet, limiting therapeutic optimization (Morrison et al., 2020; Keute and Gharabaghi, 2021). Therefore, as the vagal complex (i.e., peripheral and brainstem components) is definitely prone to bring about epigenetic modulations, notably through neuro-endocrine stimuli (Gil et al., 2013), we questioned the epigenetic role of vagus nerve, in order to promote noninvasive VNS, guided by HRV monitoring, as a universal therapy to stay healthy.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Psychiatry
- DOI:
- https://doi.org/10.17615/wr94-0254
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/fphys.2023.1279258
- ISSN:
- 1664-042X
- Journal Title:
- Frontiers in Physiology
- Journal Volume:
- 14
- Keyword:
- prevention, personalised medicine, heart rate variability, noninvasive vagus nerve stimulation, and epigenetics
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- University of Medical Sciences of Poznań, INWE’CARE Medical Center, , and INRAE Centre Val-de-Loire
- Person:
- Niezgoda A., Rangon C.M., Porges S.W., and Moyse E.
- Publisher:
- Frontiers Media SA
- Source:
- b760d23e-e65f-4f86-9117-edb89e44f958
93. Editorial: Meiosis in plants: sexual reproduction, genetic variation and crop improvement
- Title Tesim:
- Editorial: Meiosis in plants: sexual reproduction, genetic variation and crop improvement
- Creator:
- Chen, Changbin, Copenhaver, Gregory P., Wang, Yingxiang, and Wang, Chung-Ju Rachel
- Date of publication:
- 2023
- Abstract Tesim:
- Meiosis is essential for sexual reproduction and required for the formation of sperm and egg; its central events are the associations between homologous chromosomes (homologs), including pairing, synapsis, recombination and segregation. During recombination, the exchange of DNA between homologs results in new allelic combinations between the parents and offspring and among individual progeny (Wang and Copenhaver, 2018). This genetic variation is the foundation for biodiversity and speciation. The phenotypic diversity that results from genetic variation is also used to develop new elite traits during commercial plant and animal breeding practices. Thus, understanding the molecular mechanisms drive and regulate plant meiosis can accelerate crop improvement, and provide a theoretical foundation for the development and maintenance of new agricultural varieties.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Biology
- DOI:
- https://doi.org/10.17615/y4wd-s413
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/fpls.2023.1294591
- ISSN:
- 1664-462X
- Journal Title:
- Frontiers in Plant Science
- Journal Volume:
- 14
- Keyword:
- allopolyploid, FIGNL1, meiotic recombination, ZIP4, DMC1, crossover, double-strand-break, and PRD2
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- Arizona State University, , South China Agricultural University, and Academia Sinica
- Person:
- Chen, Changbin, Copenhaver, Gregory P., Wang, Yingxiang, and Wang, Chung-Ju Rachel
- Publisher:
- Frontiers Media SA
- Source:
- 73a274c6-42d1-476e-8f65-9ac728ad28b1
94. Editorial: Epigenetic insights into diagnostic and therapeutic applications
- Title Tesim:
- Editorial: Epigenetic insights into diagnostic and therapeutic applications
- Creator:
- Pattenden S.G., Jerónimo C., Perry A.S., and Fratta E.
- Date of publication:
- 2023
- Abstract Tesim:
- Studies of the heredity and variation in DNA sequence that directs normal development of all living organisms has fundamentally reshaped our understanding of human disease. However, a greater focus on an additional layer of information that does not depend on the underlying DNA sequence referred to as “epigenetics”, has emerged. Epigenetic processes have been recognized as critical for refining DNA-encoded instructions that direct cellular function, and there is increasing evidence that epigenetic dysregulation plays a central role in human disease. In contrast to irreversible genetic mutations, alterations to epigenetic pathways are dynamic, making them attractive therapeutic targets.
- Resource type:
- Article
- Affiliation Label Tesim:
- Division of Chemical Biology and Medicinal Chemistry
- DOI:
- https://doi.org/10.17615/3zhn-2e41
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/fonc.2023.1284535
- ISSN:
- 2234943X
- Journal Title:
- Frontiers in Oncology
- Journal Volume:
- 13
- Keyword:
- therapeutics, diagnostic, biomarker, cancer, and epigenetics
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- , University of Porto, University College Dublin, and IRCCS
- Person:
- Pattenden S.G., Jerónimo C., Perry A.S., and Fratta E.
- Publisher:
- Frontiers Media SA
- Source:
- 62cee2fd-1d97-4c51-ab75-691d4e973f1e
95. Editorial: Mechanisms underlying the interactions between stress and pain
- Title Tesim:
- Editorial: Mechanisms underlying the interactions between stress and pain
- Creator:
- Florea R., Géranton S.M., and Linnstaedt S.D.
- Date of publication:
- 2023
- Abstract Tesim:
- Chronic pain results from a complex interplay between biological, psychological, and socioeconomic factors. To date, numerous risk factors have been associated with the increased susceptibility to chronic pain, from mental health state and lifestyle, to gender and the presence of medical comorbidities, such as insomnia and cardiovascular diseases. Despite the identification of these risk factors, managing chronic pain, let alone preventing it, remains a major clinical challenge. This is because the specific circuits and mediators underlying the diverse components of the multidimensional experience of pain are not specific to the processing of nociceptive information and are often engaged in response to other bodily threats, including stress exposure. This prompts the need for clinical and preclinical studies that examine the multifaceted aspects of chronic pain and how these may overlap with other long-term conditions.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Anesthesiology
- DOI:
- https://doi.org/10.17615/d6ef-je19
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/fpain.2023.1285257
- ISSN:
- 2673-561X
- Journal Title:
- Frontiers in Pain Research
- Journal Volume:
- 4
- Keyword:
- vulnerability, stress, patient stratification, affective state, and pain
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- University College London and
- Person:
- Florea R., Géranton S.M., and Linnstaedt S.D.
- Publisher:
- Frontiers Media SA
- Source:
- c11d2e3e-1ade-4a32-9086-296fdbc397fe
96. Editorial: Curbing global warming with multi-scale and multi-sectoral Water-Energy-Food nexus
- Title Tesim:
- Editorial: Curbing global warming with multi-scale and multi-sectoral Water-Energy-Food nexus
- Creator:
- Hong J., Zhong H., Peng X., Chen H., and Song K.
- Date of publication:
- 2023
- Abstract Tesim:
- Food, energy, and water play fundamental roles in human life and development. The rapid growth of global population requires increasing demand for agriculture product, renewable energy, and water resource supplies. Such demands echo with the United Nation’s Sustainable Development Goals (SDGs), especially zero hunger (Goal 2), clean water and sanitation (Goal 6), and affordable and clean energy (Goal 7) in the shared blueprint for people and planet’s future.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Public Policy
- DOI:
- https://doi.org/10.17615/4qg7-e713
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/feart.2023.1271246
- ISSN:
- 2296-6463
- Journal Title:
- Frontiers in Earth Science
- Journal Volume:
- 11
- Keyword:
- global climate change, mitigation and adaptation, trilemma, global sustainability, and Food-Energy-Water nexus
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- Chongqing University, Shandong University, Jiangnan University, and
- Person:
- Hong J., Zhong H., Peng X., Chen H., and Song K.
- Publisher:
- Frontiers Media SA
- Rights Statement Label:
- In Copyright
- Source:
- a6eba28a-374b-4e8c-a2a7-58622ab3acbb
97. Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1
- Title Tesim:
- Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1
- Creator:
- Coffey A.R., Whitworth C.P., Chitrakar A., Bosque A., Selitsky S.R., Garrido C., Samir S., Soriano-Sarabia N., Goonetilleke N., Parker J.S., Xu Y., Tsai Y.H., Mann B.T., Iannone M.A., Weideman A.M.K., Clohosey M.L., Ward A.R., Kirchherr J., Sanz M., Garcia-Recio S., Copertino D., Hudgens M.G., and Jones B.R.
- Date of publication:
- 2023
- Abstract Tesim:
- Antiretroviral therapy (ART) is not curative due to the existence of cellular reservoirs of latent HIV-1 that persist during therapy. Current research efforts to cure HIV-1 infection include “shock and kill” strategies to disrupt latency using small molecules or latency-reversing agents (LRAs) to induce expression of HIV-1 enabling cytotoxic immune cells to eliminate infected cells. The modest success of current LRAs urges the field to identify novel drugs with increased clinical efficacy. Aminobisphosphonates (N-BPs) that include pamidronate, zoledronate, or alendronate, are the first-line treatment of bone-related diseases including osteoporosis and bone malignancies. Here, we show the use of N-BPs as a novel class of LRA: we found in ex vivo assays using primary cells from ART-suppressed people living with HIV-1 that N-BPs induce HIV-1 from latency to levels that are comparable to the T cell activator phytohemagglutinin (PHA). RNA sequencing and mechanistic data suggested that reactivation may occur through activation of the activator protein 1 signaling pathway. Stored samples from a prior clinical trial aimed at analyzing the effect of alendronate on bone mineral density, provided further evidence of alendronate-mediated latency reversal and activation of immune effector cells. Decay of the reservoir measured by IPDA was however not detected. Our results demonstrate the novel use of N-BPs to reverse HIV-1 latency while inducing immune effector functions. This preliminary evidence merits further investigation in a controlled clinical setting possibly in combination with therapeutic vaccination.
- Resource type:
- Article
- Affiliation Label Tesim:
- UNC Lineberger Comprehensive Cancer Center, HIV Cure Center, Department of Genetics, Department of Microbiology and Immunology, and Department of Biostatistics
- DOI:
- https://doi.org/10.17615/x3fq-v433
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/fimmu.2023.1219250
- ISSN:
- 1664-3224
- Journal Title:
- Frontiers in Immunology
- Journal Volume:
- 14
- Keyword:
- IPDA, gamma delta (γδ) T cells, shock and kill, HIV cure, latency reversing agents, and aminobisphosphonates
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- , George Washington University, and Weill Cornell Medicine
- Person:
- Coffey A.R., Whitworth C.P., Chitrakar A., Bosque A., Selitsky S.R., Garrido C., Samir S., Soriano-Sarabia N., Goonetilleke N., Parker J.S., Xu Y., Tsai Y.H., Mann B.T., Iannone M.A., Weideman A.M.K., Clohosey M.L., Ward A.R., Kirchherr J., Sanz M., Garcia-Recio S., Copertino D., Hudgens M.G., and Jones B.R.
- Publisher:
- Frontiers Media SA
- Source:
- 9d1406fa-c6ab-4cc4-ae2f-773a4c15c691
98. “When you get the HPV vaccine, it will prevent cervical cancer; it will act as a shield”: adolescent girls’ knowledge and perceptions regarding the human papillomavirus vaccine in Zambia
- Title Tesim:
- “When you get the HPV vaccine, it will prevent cervical cancer; it will act as a shield”: adolescent girls’ knowledge and perceptions regarding the human papillomavirus vaccine in Zambia
- Creator:
- Kawonga, Mary, Lubeya, Mwansa Ketty, Frank, Simone, Chibwesha, Carla J., Mukosha, Moses, and Mwanahamuntu, Mulindi
- Date of publication:
- 2023
- Abstract Tesim:
- Introduction The human papillomavirus (HPV) vaccination is an important preventive measure for HPV-related conditions such as cervical cancer. In 2019, Zambia introduced a free national HPV vaccination program for 14-year-old girls. However, the adolescents’ knowledge and perceptions regarding the HPV vaccine are not well understood. Therefore, this study aimed to understand adolescent girls’ knowledge and perceptions regarding the HPV vaccine and discuss its acceptability and uptake implications. Methods We conducted a qualitative study in the Lusaka district between June 2021 and November 2021 using semi-structured interviews with adolescent girls aged 15–18 years regardless of their HPV vaccination status. Interviews were transcribed verbatim, and NVIVO 12 was used for data management and analysis. We coded transcripts deductively and inductively based on emerging themes. Perceptions were coded using the health belief model constructs. Results We interviewed 30 adolescent girls to reach saturation. Seventeen girls reported having received at least one dose of the HPV vaccine. Participants expressed variable knowledge and awareness about HPV and the HPV vaccine. Participants exhibited positive attitudes towards the HPV vaccine and perceived it as beneficial. However, there were multiple perceived barriers to vaccination, such as the need for parental consent, not being in school, concerns about vaccine side effects, and belief in myths and misinformation. Conclusion The adolescent girls in this study showed variable knowledge and positive attitudes toward the HPV vaccine despite the many perceived barriers. To support increased HPV vaccine acceptability and uptake among adolescent girls in Zambia, it is critical to actively engage stakeholders involved in HPV vaccination, such as adolescents and their parents, and debunk myths and misconceptions about HPV vaccination. Health education in schools and communities should be implemented to increase knowledge about HPV and HPV vaccination among adolescents and their parents.
- Resource type:
- Article
- Affiliation Label Tesim:
- North Carolina Translational and Clinical Sciences Institute
- DOI:
- https://doi.org/10.17615/t5qq-9k57
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/frhs.2023.1208458
- ISSN:
- 2813-0146
- Journal Title:
- Frontiers in Health Services
- Journal Volume:
- 3
- Keyword:
- myths and misinformation, HPV vaccine acceptability, COVID-19 vaccine, HPV vaccine uptake, parental consent, health belief model, and cervical cancer
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- Charlotte Maxeke Johannesburg Academic Hospital, University of Zambia,, , Helen JosephHospital, and University of theWitwatersrand
- Person:
- Kawonga, Mary, Lubeya, Mwansa Ketty, Frank, Simone, Chibwesha, Carla J., Mukosha, Moses, and Mwanahamuntu, Mulindi
- Publisher:
- Frontiers Media SA
- Source:
- 06f2b3df-2357-4b51-b7eb-e383c089de0a
99. A review of neurological health disparities in Peru
- Title Tesim:
- A review of neurological health disparities in Peru
- Creator:
- Diaz M.M., Almubaslat F., and Sanchez-Boluarte S.S.
- Date of publication:
- 2023
- Abstract Tesim:
- Peru is a historically unique and culturally diverse Latin American country. As a low-to-middle-income country (LMIC), Peru faces health implications from the spread of communicable diseases as well as a growing rate of noncommunicable diseases, both of which have been worsened by the recent COVID-19 pandemic’s impact on the national health system. Over the past two decades, the country has aimed to improve health access for its population through various efforts described in this review. Despite this, there are notable neurological health disparities that exist today. This narrative review investigates such disparities through the leading neurological contributors to the national burden of disease in the country, including migraine headaches, cerebrovascular disease, and dementia. Public health disparities that contribute to other major neurological diseases in the country, including epilepsy, neurocysticercosis, Chagas disease, multiple sclerosis, traumatic brain injury, traumatic and non-traumatic spinal cord injuries are also investigated. We also explore potential solutions for overcoming the various neurological health disparities covered in this review that may be applied through public policies, as well as in similar LMICs in Latin America. By overcoming such disparities, the country may be able to successfully address the major contributors of neurological disease burden and create a healthcare environment that can sustainably and equitably improve health outcomes for Peruvian people.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Neurology
- DOI:
- https://doi.org/10.17615/59dp-mz38
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/fpubh.2023.1210238
- ISSN:
- 2296-2565
- Journal Title:
- Frontiers in Public Health
- Journal Volume:
- 11
- Keyword:
- Latin America, disparities, neurological health, Peru, and narrative review
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- and Instituto Nacional de Ciencias Neurológicas
- Person:
- Diaz M.M., Almubaslat F., and Sanchez-Boluarte S.S.
- Publisher:
- Frontiers Media SA
- Source:
- 46d23bd5-25c3-43d8-9c64-b6b7f25ec614
100. A homozygous missense variant in the YG box domain in an individual with severe spinal muscular atrophy: a case report and variant characterization
- Title Tesim:
- A homozygous missense variant in the YG box domain in an individual with severe spinal muscular atrophy: a case report and variant characterization
- Creator:
- Fan, Zheng, Hunter, Senyene E., Sneddon, Tam P., Shiloh-Malawsky, Yael, Li, Leping, Perera, Lalith, Varghese, Sonia A., Powell, Cynthia M., and Matera, A. Gregory
- Date of publication:
- 2023
- Abstract Tesim:
- The vast majority of severe (Type 0) spinal muscular atrophy (SMA) cases are caused by homozygous deletions of survival motor neuron 1 (SMN1). We report a case in which the patient has two copies of SMN1 but clinically presents as Type 0 SMA. The patient is an African American male carrying a homozygous maternally inherited missense variant (c.796T>C) in a cis-oriented SMN1 duplication on one chromosome and an SMN1 deletion on the other chromosome (genotype: 2*+0). Initial extensive genetic workups including exome sequencing were negative. Deletion analysis used in the initial testing for SMA also failed to detect SMA as the patient has two copies of SMN1. Because of high clinical suspicion, SMA diagnosis was finally confirmed based on full-length SMN1 sequencing. The patient was initially treated with risdiplam and later gene therapy with onasemnogene abeparvovec at 5 months without complications. The patient’s muscular weakness has stabilized with mild improvement. The patient is now 28 months old and remains stable and diffusely weak, with stable respiratory ventilatory support. This case highlights challenges in the diagnosis of SMA with a non-deletion genotype and provides a clinical example demonstrating that disruption of functional SMN protein polymerization through an amino acid change in the YG-box domain represents a little known but important pathogenic mechanism for SMA. Clinicians need to be mindful about the limitations of the current diagnostic approach for SMA in detecting non-deletion genotypes.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Neurology, Department of Pathology and Laboratory Medicine, Department of Pediatrics, and Integrative Program for Biological and Genome Sciences
- DOI:
- https://doi.org/10.17615/7dt9-nx77
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3389/fncel.2023.1259380
- ISSN:
- 1662-5102
- Journal Title:
- Frontiers in Cellular Neuroscience
- Journal Volume:
- 17
- Keyword:
- YG Box, g.27134T>G polymorphism, c.796T>C variant, spinal muscular atrophy (SMA), modeling, non-deletion, and African American
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- and National Institute of Environmental Health Sciences
- Person:
- Fan, Zheng, Hunter, Senyene E., Sneddon, Tam P., Shiloh-Malawsky, Yael, Li, Leping, Perera, Lalith, Varghese, Sonia A., Powell, Cynthia M., and Matera, A. Gregory
- Publisher:
- Frontiers Media SA
- Source:
- 0b47036b-50e3-4874-9aec-4e8e74fb851e
Collection Details
- Total items
-
762
- Size
-
unknown
- Date created
-
May 26, 2022