Methodological Advances in Evaluating Abuse Deterrent Opioid Analgesics

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This was a 4-year research and dissemination project which occurred from 2018 to 2022 that leveraged emerging advances in data connectivity and established new standards for methodological rigor in the evaluation of opioid analgesics. The overall goal was to develop and disseminate new open source epidemiologic tools to facilitate evaluation of abuse deterrent formulations [ADFs] and understanding of overdose mortality. The work was conducted at the University of Kentucky, University of North Carolina, University of Florida, with partnership with IBM Watson Health and NC Survivors Union. The suite of studies was primarily funded by the US Food and Drug Administration...

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