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UNC-authored articles published by MDPI
Works (441)
61. Efficacy of Guardian Cap Soft-Shell Padding on Head Impact Kinematics in American Football: Pilot Findings
- Title Tesim:
- Efficacy of Guardian Cap Soft-Shell Padding on Head Impact Kinematics in American Football: Pilot Findings
- Creator:
- Lauck, Bradley J., Mincberg, David L., Sinnott, Aaron M., Pinapaka, Hari, Van Dyke, Charles, Chandler, Madison C., and Mihalik, Jason P.
- Date of publication:
- 2023
- Abstract Tesim:
- Sport-related concussion prevention strategies in collision sports are a primary interest for sporting organizations and policy makers. After-market soft-shell padding purports to augment the protective capabilities of standard football helmets and to reduce head impact severity. We compared head impact kinematics [peak linear acceleration (PLA) and peak rotational acceleration (PRA)] in athletes wearing Guardian Cap soft-shell padding to teammates without soft-shell padding. Ten Division I college football players were enrolled [soft-shell padding (SHELL) included four defensive linemen and one tight end; non-soft-shell (CONTROL) included two offensive linemen, two defensive linemen, and one tight end]. Participants wore helmets equipped with the Head Impact Telemetry System to quantify PLA (g) and PRA (rad/s2) during 14 practices. Two-way ANOVAs were conducted to compare log-transformed PLA and PRA between groups across helmet location and gameplay characteristics. In total, 968 video-confirmed head impacts between SHELL (n = 421) and CONTROL (n = 547) were analyzed. We observed a Group x Stance interaction for PRA (F1,963 = 7.21; p = 0.007) indicating greater PRA by SHELL during 2-point stance and lower PRA during 3- or 4-point stances compared to CONTROL. There were no between-group main effects. Protective soft-shell padding did not reduce head impact kinematic outcomes among college football athletes.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Exercise and Sport Science and University of North Carolina at Chapel Hill
- DOI:
- https://doi.org/10.17615/1tn6-f783
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/ijerph20216991
- ISSN:
- 1660-4601
- Journal Issue:
- 21
- Journal Title:
- International Journal of Environmental Research and Public Health
- Journal Volume:
- 20
- Keyword:
- repetitive head impact exposure, equipment add-on, intervention strategies, injury prevention, brain injury, and concussion
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- Page Start:
- 6991
- Person:
- Lauck, Bradley J., Mincberg, David L., Sinnott, Aaron M., Pinapaka, Hari, Van Dyke, Charles, Chandler, Madison C., and Mihalik, Jason P.
- Publisher:
- MDPI
- Source:
- 4834c0f2-d704-4899-b01e-190743b3fd7f
62. “Caregiving Youth” and the Patchwork History of Recognition in the United States
- Title Tesim:
- “Caregiving Youth” and the Patchwork History of Recognition in the United States
- Creator:
- Olson, Elizabeth and Edmonds, Leiha
- Date of publication:
- 2023
- Abstract Tesim:
- This article examines the U.S. legislative and policy landscape and its historical and contemporary recognition of young people as caregivers and their importance to public health, both as care providers and as a category of special concern for overall wellbeing. Drawing on feminist geographies of health to situate a historical analysis, we aim to answer two key questions: First, what is the history of recognition of caregiving youth in key moments of federal action to address family caregiving needs? Second, how might we use this history to better understand and analyze the patchwork geography of caregiving youth recognition in the U.S. and other countries that similarly lack formal national policy recognition to improve and enhance public health? We use the term patchwork to describe how federal recognition of caregiving youth in broader debates about public health is uneven across both time and space, and contingent upon civil society, non-profit organizations, and researchers working in and with geographically bound communities. Our results illustrate how a focus on the relationships of recognition, both in the past and the present and at local and national scales, reveals a different perspective on caregiving youth in the U.S. with a much more complex history than previously identified. The article describes how relationships established in the absence of federal policy or legislation are sometimes directed towards building more formal recognition, and other times with the goal of changing practices in a specific location.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Geography
- DOI:
- https://doi.org/10.17615/zt2v-9y28
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/ijerph20206920
- ISSN:
- 1660-4601
- Journal Issue:
- 20
- Journal Title:
- International Journal of Environmental Research and Public Health
- Journal Volume:
- 20
- Keyword:
- feminist geography, history, caregiving youth, care, critical health geographies, and United States
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- Page Start:
- 6920
- Person:
- Olson, Elizabeth and Edmonds, Leiha
- Publisher:
- MDPI
- Source:
- 8b23d45d-45ca-4447-9724-c77e67ec64dc
63. Unlocking the Molecular Secrets of Antifolate Drug Resistance: A Multi-Omics Investigation of the NCI-60 Cell Line Panel
- Title Tesim:
- Unlocking the Molecular Secrets of Antifolate Drug Resistance: A Multi-Omics Investigation of the NCI-60 Cell Line Panel
- Creator:
- Rushing, Blake R.
- Date of publication:
- 2023
- Abstract Tesim:
- Drug resistance continues to be a significant problem in cancer therapy, leading to relapse and associated mortality. Although substantial progress has been made in understanding drug resistance, significant knowledge gaps remain concerning the molecular underpinnings that drive drug resistance and which processes are unique to certain drug classes. The NCI-60 cell line panel program has evaluated the activity of numerous anticancer agents against many common cancer cell line models and represents a highly valuable resource to study intrinsic drug resistance. Furthermore, great efforts have been undertaken to collect high-quality omics datasets to characterize these cell lines. The current study takes these two sources of data—drug response and omics profiles—and uses a multi-omics investigation to uncover molecular networks that differentiate cancer cells that are sensitive or resistant to antifolates, which is a commonly used class of anticancer drugs. Results from a combination of univariate and multivariate analyses showed numerous metabolic processes that differentiate sensitive and resistant cells, including differences in glycolysis and gluconeogenesis, arginine and proline metabolism, beta-alanine metabolism, purine metabolism, and pyrimidine metabolism. Further analysis using multivariate and integrated pathway analysis indicated purine metabolism as the major metabolic process separating cancer cells sensitive or resistant to antifolates. Additional pathways differentiating sensitive and resistant cells included autophagy-related processes (e.g., phagosome, lysosome, autophagy, mitophagy) and adhesion/cytoskeleton-related pathways (e.g., focal adhesion, regulation of actin cytoskeleton, tight junction). Volcano plot analysis and the receiver operating characteristic (ROC) curves of top selected variables differentiating Q1 and Q4 revealed the importance of genes involved in the regulation of the cytoskeleton and extracellular matrix (ECM). These results provide novel insights toward mechanisms of intrinsic antifolate resistance as it relates to interactions between nucleotide metabolism, autophagy, and the cytoskeleton. These processes should be evaluated in future studies to potentially derive novel therapeutic strategies and personalized treatment approaches to improve antifolate response.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Nutrition
- DOI:
- https://doi.org/10.17615/fwxp-zj88
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/biomedicines11092532
- ISSN:
- 2227-9059
- Journal Issue:
- 9
- Journal Title:
- Biomedicines
- Journal Volume:
- 11
- Keyword:
- multi-omics, drug resistance, copy number variants, antifolates, DNA methylation, cancer, metabolomics, metabolism, transcriptomics, and proteomics
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- Page Start:
- 2532
- Person:
- Rushing, Blake R.
- Publisher:
- Multidisciplinary Digital Publishing Institute (MDPI)
- Source:
- 95cbed3a-46fa-4f30-9748-630908fcb15c
64. Two-Way Immersion Classrooms during the COVID-19 Pandemic: Parent and Teacher Perceptions of Student Learning
- Title Tesim:
- Two-Way Immersion Classrooms during the COVID-19 Pandemic: Parent and Teacher Perceptions of Student Learning
- Creator:
- Franco-Jenkins X., Winsler A., Ordoñez Rojas D., and LaForett D.R.
- Date of publication:
- 2023
- Abstract Tesim:
- The present study examined parents’ and teachers’ perceptions of student learning in Spanish–English Dual Language Education (DLE) programs during the COVID-19 pandemic. The participants included 72 parents of students from kindergarten to second grade and eight teachers in two schools in the southeastern U.S. Parents retrospectively reported their perceptions of their children’s instruction and learning experiences in English and Spanish during the 2020–2021 school year. Teachers reported if their students had opportunities to practice oral bilingual skills and their perception of students’ improvement in English and Spanish skills. Parents reported that there were more opportunities to practice English than there were to practice Spanish. Teachers reported that remote instruction offered fewer opportunities than hybrid instruction did to practice oral language skills. Overall, the teachers agreed that students’ language skills in English and Spanish improved. Similarly, the parents agreed that students’ language skills improved; however, they reported that their English skills improved more than their Spanish skills did. Student and family background factors, such as language fluency and parental education, were negatively associated with barriers to remote access. Implications for future research and suggestions for supporting students attending DLE programs during remote instruction are offered.
- Resource type:
- Article
- Affiliation Label Tesim:
- Frank Porter Graham Child Development Institute
- DOI:
- https://doi.org/10.17615/ds8y-d355
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/educsci13090946
- ISSN:
- 2227-7102
- Journal Issue:
- 9
- Journal Title:
- Education Sciences
- Journal Volume:
- 13
- Keyword:
- bilingual education, remote instruction, elementary school, two-way immersion (TWI), COVID-19, and dual language education
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- and George Mason University
- Person:
- Franco-Jenkins X., Winsler A., Ordoñez Rojas D., and LaForett D.R.
- Publisher:
- Multidisciplinary Digital Publishing Institute (MDPI)
- Source:
- 2f5bb95c-a37e-49df-905c-b67c29def70c
65. The Role of Dietary Protein in Body Weight Regulation among Active-Duty Military Personnel during Energy Deficit: A Systematic Review
- Title Tesim:
- The Role of Dietary Protein in Body Weight Regulation among Active-Duty Military Personnel during Energy Deficit: A Systematic Review
- Creator:
- Anderson R.E., 3rd, Casperson S.L., Kho H., and Flack K.D.
- Date of publication:
- 2023
- Abstract Tesim:
- Active-duty military personnel are subjected to sustained periods of energy deficit during combat and training, leaving them susceptible to detrimental reductions in body weight. The importance of adequate dietary protein intake during periods of intense physical training is well established, where previous research has primarily focused on muscle protein synthesis, muscle recovery, and physical performance. Research on how protein intake may influence body weight regulation in this population is lacking; therefore, the objective of this review was to evaluate the role of dietary protein in body weight regulation among active-duty military during an energy deficit. A literature search based on fixed inclusion and exclusion criteria was performed. English language peer-reviewed journal articles from inception to 3 June 2023 were selected for extraction and quality assessment. Eight studies were identified with outcomes described narratively. The study duration ranged from eight days to six months. Protein was directly provided to participants in all studies except for one. Three studies supplied additional protein via supplementation. The Downs and Black Checklist was used to assess study quality. Five studies were classified as good, two as fair, and one as excellent. All studies reported mean weight loss following energy deficit: the most severe was 4.0 kg. Protein dose during energy deficit varied from 0.5 g/kg/day to 2.4 g/kg/day. Six studies reported mean reductions in fat mass, with the largest being 4.5 kg. Four studies reported mean reductions in fat-free mass, while two studies reported an increase. Results support the recommendation that greater than 0.8 g/kg/day is necessary to mitigate the impact of energy deficit on a decline in lean body mass, while intakes up to 1.6 g/kg/day may be preferred. However, exact recommendations cannot be inferred as the severity and duration of energy deficit varied across studies. Longer and larger investigations are needed to elucidate protein’s role during energy deficit in active-duty military.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Nutrition
- DOI:
- https://doi.org/10.17615/yzzq-5389
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/nu15183948
- ISSN:
- 2072-6643
- Journal Issue:
- 18
- Journal Title:
- Nutrients
- Journal Volume:
- 15
- Keyword:
- active-duty military, protein, fat-free mass, body weight, fat mass, body composition, and energy deficit
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- , U.S. Department of Agriculture, and University of Kentucky
- Person:
- Anderson R.E., 3rd, Casperson S.L., Kho H., and Flack K.D.
- Publisher:
- Multidisciplinary Digital Publishing Institute (MDPI)
- Source:
- 14a7744a-1af7-49e2-9d7b-5df1301f1803
66. The Effect of Polyphenols, Minerals, Fibers, and Fruits on Irritable Bowel Syndrome: A Systematic Review
- Title Tesim:
- The Effect of Polyphenols, Minerals, Fibers, and Fruits on Irritable Bowel Syndrome: A Systematic Review
- Creator:
- Surdea-Blaga T., Ismaiel A., Brata V.D., Incze V., Chiarioni G., Dumitrascu D.I., Duse T.A., Popa S.L., and Pop C.
- Date of publication:
- 2023
- Abstract Tesim:
- Background: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain, bloating, and changes in bowel habits. Various dietary factors have been implicated in the pathogenesis and management of IBS symptoms. This systematic review aims to evaluate the effects of polyphenols, minerals, fibers, and fruits on the symptoms and overall well-being of individuals with IBS. Materials and Methods: A comprehensive literature search was conducted in several electronic databases, including PubMed, Scopus, and Web of Science. Studies published up until July 2023 were included. Results: The selected studies varied in terms of study design, participant characteristics, intervention duration, and outcome measures. Overall, the findings suggest that dietary interventions involving polyphenols, minerals, fibers, and fruits can have a positive impact on IBS symptoms. Dietary fiber supplementation, particularly soluble fiber, has been associated with reduced bloating and enhanced stool consistency. Conclusions: This systematic review provides evidence supporting the beneficial effects of polyphenols, minerals, fibers, and fruits in IBS patients. These dietary components hold promise as complementary approaches for managing IBS symptoms. However, due to the heterogeneity of the included studies and the limited number of high-quality randomized controlled trials, further well-designed trials are warranted to establish the optimal dosages, duration, and long-term effects of these interventions. Understanding the role of specific dietary components in IBS management may pave the way for personalized dietary recommendations and improve the quality of life for individuals suffering from this complex disorder.
- Resource type:
- Article
- Affiliation Label Tesim:
- Division of Gastroenterology and Hepatology
- DOI:
- https://doi.org/10.17615/a7fr-9s89
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/nu15184070
- ISSN:
- 2072-6643
- Journal Issue:
- 18
- Journal Title:
- Nutrients
- Journal Volume:
- 15
- Keyword:
- IBS, polyphenols, nonpharmacological therapy, fibers, fruits, and minerals
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- “Iuliu Hatieganu” University of Medicine and Pharmacy and
- Person:
- Surdea-Blaga T., Ismaiel A., Brata V.D., Incze V., Chiarioni G., Dumitrascu D.I., Duse T.A., Popa S.L., and Pop C.
- Publisher:
- Multidisciplinary Digital Publishing Institute (MDPI)
- Source:
- bc4116c0-f3a2-4eb2-9c93-98debc2efde2
67. Research Progress on Features and Characteristics of Rural Settlements: Literature Distribution, Key Issues, and Development Trends
- Title Tesim:
- Research Progress on Features and Characteristics of Rural Settlements: Literature Distribution, Key Issues, and Development Trends
- Creator:
- Li, Chun, Gu, Guangcan, Yang, Huihui, An, Na, Yan, Kai, Yang, Ende, and Yao, Qiang
- Date of publication:
- 2023
- Abstract Tesim:
- During the development of rural settlements, the loss of distinctive rural characteristics, caused by the contradiction between urban expansion and the ideal of pastoralism, has attracted widespread attention from researchers worldwide. To effectively understand the development and trends of the Research of Features and Characteristics of Rural Settlements (abbreviated as RFCRS), this paper uses the knowledge mapping software CiteSpace to conduct co-citation analysis, research collaboration analysis, keyword clustering, and keyword co-occurrence. The study analyzes the basic concepts, the literature distribution characteristics, research clusters, key issues, and development trends of RFCRS. The research found that the current key research topics in RFCRS include “Eco-logical services and environmental protection of rural settlements”, “Sustainable planning and architectural design issues of rural settlements”, and “Human settlement environment and service facility construction of rural settlements”. This paper predicts that future RFCRS research trends will focus on the study of landscape features and characteristics based on ecology, climate, and aesthetics; study of architectural features and characteristics based on characteristic factors and hierarchical structure; and research on rural revitalization based on sustainable development principles. The paper also offers four priority research suggestions for researchers from different disciplines.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of City and Regional Planning
- DOI:
- https://doi.org/10.17615/pzsf-je23
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/buildings13102457
- ISSN:
- 2075-5309
- Journal Issue:
- 10
- Journal Title:
- Buildings
- Journal Volume:
- 13
- Keyword:
- bibliometric, knowledge mapping, development trend, rural settlements, features and characteristics, literature distribution, and key issues
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- Tongji University, Chongqing University, and
- Page Start:
- 2457
- Person:
- Li, Chun, Gu, Guangcan, Yang, Huihui, An, Na, Yan, Kai, Yang, Ende, and Yao, Qiang
- Publisher:
- Multidisciplinary Digital Publishing Institute (MDPI)
- Source:
- 121218e3-0a2e-4ba8-a66a-1b7aa943c785
68. Patterns of Cough Medication Prescribing among Patients with Chronic Cough in Florida: 2012–2021
- Title Tesim:
- Patterns of Cough Medication Prescribing among Patients with Chronic Cough in Florida: 2012–2021
- Creator:
- Ke, Xuehua, Jones, Bobby, Sher, Mandel R., Yang, Seonkyeong, Hincapie-Castillo, Juan M., Schelfhout, Jonathan, Huang, Shu, Wilson, Debbie L., Lo-Ciganic, Wei-Hsuan, and Ding, Helen
- Date of publication:
- 2023
- Abstract Tesim:
- Among patients with chronic cough (CC) in the 2012–2021 statewide OneFlorida Clinical Research Consortium database, we examined trends in cough medication (CM) prescribing prevalence over time in repeated cross-sectional analyses and identified distinct CM utilization trajectories using group-based trajectory modeling (GBTM) in a retrospective cohort study. Among eligible adults (≥18 years) without cancer/benign respiratory tumor diagnoses, we identified CC patients and non-CC patients with any cough-related diagnosis. In the GBTM analysis, we calculated the number of monthly prescriptions for any CMs (excluding gabapentinoids) during the 12 months from the first qualifying cough event to identify distinct utilization trajectories. From 2012 to 2021, benzonatate (9.6% to 26.1%), dextromethorphan (5.2% to 8.6%), and gabapentinoid (5.3% to 14.4%) use increased among CC patients, while opioid antitussive use increased from 2012 to 2015 and decreased thereafter (8.4% in 2012, 14.7% in 2015, 6.7% in 2021; all p < 0.001). Of 15,566 CC patients and 655,250 non-CC patients identified in the GBTM analysis, CC patients had substantial burdens of respiratory/non-respiratory comorbidities and healthcare service and concomitant medication use compared to non-CC patients. Among CC patients, GBTM identified three distinct CM utilization trajectories: (1) no CM use (n = 11,222; 72.1%); (2) declining CM use (n = 4105; 26.4%); and (3) chronic CM use (n = 239; 1.5%). CC patients in Florida had limited CM use with increasing trends in use of benzonatate, dextromethorphan, and gabapentinoids and a decreasing trend in opioid antitussive use. CC patients, particularly with chronic prescription CM use, experienced substantial disease burden.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Epidemiology
- DOI:
- https://doi.org/10.17615/ne71-2384
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/jcm12196286
- ISSN:
- 2077-0383
- Journal Issue:
- 19
- Journal Title:
- Journal of Clinical Medicine
- Journal Volume:
- 12
- Keyword:
- drug utilization, gabapentinoid, group-based trajectory modeling, chronic cough, opioid antitussive, cough hypersensitivity syndrome, dextromethorphan, cough, antitussive, and benzonatate
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- Merck & Co., Inc, University of Florida, Center for Cough, and
- Page Start:
- 6286
- Person:
- Ke, Xuehua, Jones, Bobby, Sher, Mandel R., Yang, Seonkyeong, Hincapie-Castillo, Juan M., Schelfhout, Jonathan, Huang, Shu, Wilson, Debbie L., Lo-Ciganic, Wei-Hsuan, and Ding, Helen
- Publisher:
- MDPI
- Source:
- 739cd80f-e573-458d-b1c2-bcfcd6f5dfec
69. Patient Perspectives of Barriers and Facilitators for the Uptake of Pharmacogenomic Testing in Veterans Affairs’ Pharmacogenomic Testing for the Veterans (PHASER) Program
- Title Tesim:
- Patient Perspectives of Barriers and Facilitators for the Uptake of Pharmacogenomic Testing in Veterans Affairs’ Pharmacogenomic Testing for the Veterans (PHASER) Program
- Creator:
- Gutierrez-Meza, Diana, Gavin, Kara L., Sperber, Nina, Silva, Abigail, Melendez, Karina, Hung, Allison, Voils, Corrine I., Alagoz, Esra, Roberts, Megan C., Wu, Rebekah Ryanne, Pati, Bhabna, and Voora, Deepak
- Date of publication:
- 2023
- Abstract Tesim:
- We applied implementation science frameworks to identify barriers and facilitators to veterans’ acceptance of pharmacogenomic testing (PGx), which was made available as a part of clinical care at 25 VA medical centers. We conducted 30 min interviews with veterans who accepted (n = 14), declined (n = 9), or were contemplating (n = 8) PGx testing. Six team members coded one transcript from each participant group to develop the codebook and finalize definitions. Three team members coded the remaining 28 transcripts and met regularly with the larger team to reach a consensus. The coders generated a matrix of implementation constructs by testing status to identify the similarities and differences between accepters, decliners, and contemplators. All groups understood the PGx testing procedures and possible benefits. In the decision-making, accepters prioritized the potential health benefits of PGx testing, such as reducing side effects or the number of medications. In contrast, decliners prioritized the possibilities of data breach or the negative impact on healthcare insurance or Veterans Affairs benefits. Contemplators desired to speak to a provider to learn more before making a decision. Efforts to improve the clarity of data security and the impact on benefits may improve veterans’ abilities to make more informed decisions about whether to undergo PGx testing.
- Resource type:
- Article
- Affiliation Label Tesim:
- Eshelman School of Pharmacy
- DOI:
- https://doi.org/10.17615/xwxh-9529
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/jpm13091367
- ISSN:
- 2075-4426
- Journal Issue:
- 9
- Journal Title:
- Journal of Personalized Medicine
- Journal Volume:
- 13
- Keyword:
- enablers, veterans, pharmacotherapy, facilitators, barriers, and PGx testing
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- University of Wisconsin, Duke University, Loyola University Chicago, and
- Page Start:
- 1367
- Person:
- Gutierrez-Meza, Diana, Gavin, Kara L., Sperber, Nina, Silva, Abigail, Melendez, Karina, Hung, Allison, Voils, Corrine I., Alagoz, Esra, Roberts, Megan C., Wu, Rebekah Ryanne, Pati, Bhabna, and Voora, Deepak
- Publisher:
- MDPI
- Source:
- 7bf64938-defe-4396-8581-780b03285789
70. One-Step Clustering with Adaptively Local Kernels and a Neighborhood Kernel
- Title Tesim:
- One-Step Clustering with Adaptively Local Kernels and a Neighborhood Kernel
- Creator:
- Chen, Cuiling, Li, Zhi, Xiao, Hongbin, Hu, Zhijun, and Ma, Junbo
- Date of publication:
- 2023
- Abstract Tesim:
- Among the methods of multiple kernel clustering (MKC), some adopt a neighborhood kernel as the optimal kernel, and some use local base kernels to generate an optimal kernel. However, these two methods are not synthetically combined together to leverage their advantages, which affects the quality of the optimal kernel. Furthermore, most existing MKC methods require a two-step strategy to cluster, i.e., first learn an indicator matrix, then executive clustering. This does not guarantee the optimality of the final results. To overcome the above drawbacks, a one-step clustering with adaptively local kernels and a neighborhood kernel (OSC-ALK-ONK) is proposed in this paper, where the two methods are combined together to produce an optimal kernel. In particular, the neighborhood kernel improves the expression capability of the optimal kernel and enlarges its search range, and local base kernels avoid the redundancy of base kernels and promote their variety. Accordingly, the quality of the optimal kernel is enhanced. Further, a soft block diagonal (BD) regularizer is utilized to encourage the indicator matrix to be BD. It is helpful to obtain explicit clustering results directly and achieve one-step clustering, then overcome the disadvantage of the two-step strategy. In addition, extensive experiments on eight data sets and comparisons with six clustering methods show that OSC-ALK-ONK is effective.
- Resource type:
- Article
- Affiliation Label Tesim:
- Department of Psychiatry
- DOI:
- https://doi.org/10.17615/s5bq-q735
- Edition:
- Publisher
- Identifier:
- https://dx.doi.org/10.3390/math11183950
- ISSN:
- 2227-7390
- Journal Issue:
- 18
- Journal Title:
- Mathematics
- Journal Volume:
- 11
- Keyword:
- multiple kernel clustering, block diagonal representation, local kernels, and neighborhood kernel
- Language Label:
- English
- License Label:
- Attribution 4.0 International
- ORCID:
- Other Affiliation:
- Guangxi Normal University and
- Page Start:
- 3950
- Person:
- Chen, Cuiling, Li, Zhi, Xiao, Hongbin, Hu, Zhijun, and Ma, Junbo
- Publisher:
- MDPI
- Source:
- 8db1ac40-2377-43f6-971a-d392cfe86491
Collection Details
- Total items
-
441
- Size
-
unknown
- Date created
-
May 26, 2022