Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit
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Hall, Matthew D, et al. Report of the National Institutes of Health Sars-cov-2 Antiviral Therapeutics Summit. 2021. https://doi.org/10.17615/mza2-ps17APA
Hall, M., Anderson, J., Anderson, A., Baker, D., Bradner, J., Brimacombe, K., Campbell, E., Corbett, K., Carter, K., Cherry, S., Chiang, L., Cihlar, T., De Wit, E., Denison, M., Disney, M., Fletcher, C., Ford Scheimer, S., Götte, M., Grossman, A., Hayden, F., Hazuda, D., Lanteri, C., Marston, H., Mesecar, A., Moore, S., Nwankwo, J., O&Apos;Rear, J., Painter, G., Singh Saikatendu, K., Schiffer, C., Sheahan, T., Shi, P., Smyth, H., Sofia, M., Weetall, M., Weller, S., Whitley, R., Fauci, A., Austin, C., Collins, F., Conley, A., & Davis, M. (2021). Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit. https://doi.org/10.17615/mza2-ps17Chicago
Hall, Matthew D, James M Anderson, Annaliesa Anderson, David Baker, Jay Bradner, Kyle R Brimacombe, Elizabeth A Campbell et al. 2021. Report of the National Institutes of Health Sars-Cov-2 Antiviral Therapeutics Summit. https://doi.org/10.17615/mza2-ps17- Creator
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Hall, Matthew D
- Other Affiliation: National Institutes of Health
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Anderson, James M
- Other Affiliation: National Institutes of Health
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Anderson, Annaliesa
- Other Affiliation: Pfizer
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Baker, David
- Other Affiliation: University of Washington
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Bradner, Jay
- Other Affiliation: Novartis Institutes for BioMedical Research
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Brimacombe, Kyle R
- Other Affiliation: National Institutes of Health
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Campbell, Elizabeth A
- Other Affiliation: The Rockefeller University
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Corbett, Kizzmekia S
- Other Affiliation: National Institutes of Health
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Carter, Kara
- Other Affiliation: Evotec
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Cherry, Sara
- Other Affiliation: University of Pennsylvania
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Chiang, Lillian
- Other Affiliation: Evrys Bio
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Cihlar, Tomas
- Other Affiliation: Gilead Sciences
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de Wit, Emmie
- Other Affiliation: National Institutes of Health
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Denison, Mark
- Other Affiliation: Vanderbilt University
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Disney, Matthew
- Other Affiliation: Scripps Research
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Fletcher, Courtney V
- Other Affiliation: University of Nebraska Medical Center
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Ford-Scheimer, Stephanie L
- Other Affiliation: National Institutes of Health
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Götte, Matthias
- Other Affiliation: University of Alberta
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Grossman, Abigail C
- Other Affiliation: National Institutes of Health
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Hayden, Frederick G
- Other Affiliation: University of Virginia
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Hazuda, Daria J
- Other Affiliation: Merck and Co
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Lanteri, Charlotte A
- Other Affiliation: Walter Reed Army Institute of Research
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Marston, Hilary
- Other Affiliation: National Institutes of Health
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Mesecar, Andrew D
- Other Affiliation: Purdue University
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Moore, Stephanie
- Other Affiliation: University of Alabama at Birmingham
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Nwankwo, Jennifer O
- Other Affiliation: 1910 Genetics Inc.
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O'Rear, Jules
- Other Affiliation: US Food and Drug Administration
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Painter, George
- Other Affiliation: Emory University
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Singh Saikatendu, Kumar
- Other Affiliation: Takeda California, Inc
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Schiffer, Celia A
- Other Affiliation: University of Massachusetts Medical School
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Sheahan, Timothy P
- Affiliation: Gillings School of Global Public Health, Department of Epidemiology
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Shi, Pei-Yong
- Other Affiliation: University of Texas Medical Branch
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Smyth, Hugh D
- Other Affiliation: University of Texas at Austin
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Sofia, Michael J
- Other Affiliation: Arbutus Biopharma, Inc
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Weetall, Marla
- Other Affiliation: PTC Therapeutics, Inc
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Weller, Sandra K
- Other Affiliation: University of Connecticut School of Medicine
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Whitley, Richard
- Other Affiliation: University of Alabama at Birmingham
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Fauci, Anthony S
- Other Affiliation: National Institutes of Health
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Austin, Christopher P
- Other Affiliation: National Institutes of Health
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Collins, Francis S
- Other Affiliation: National Institutes of Health
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Conley, Anthony J
- Other Affiliation: National Institutes of Health
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Davis, Mindy I
- Other Affiliation: National Institutes of Health
- Abstract
- The NIH Virtual SARS-CoV-2 Antiviral Summit, held on 6 November 2020, was organized to provide an overview on the status and challenges in developing antiviral therapeutics for coronavirus disease 2019 (COVID-19), including combinations of antivirals. Scientific experts from the public and private sectors convened virtually during a live videocast to discuss severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets for drug discovery as well as the preclinical tools needed to develop and evaluate effective small-molecule antivirals. The goals of the Summit were to review the current state of the science, identify unmet research needs, share insights and lessons learned from treating other infectious diseases, identify opportunities for public-private partnerships, and assist the research community in designing and developing antiviral therapeutics. This report includes an overview of therapeutic approaches, individual panel summaries, and a summary of the discussions and perspectives on the challenges ahead for antiviral development.
- Date of publication
- 2021
- Keyword
- DOI
- Identifier
- Resource type
- Article
- Rights statement
- In Copyright
- License
- Public Domain Mark 1.0
- Journal title
- The Journal of Infectious Diseases
- Journal volume
- 224
- Journal issue
- Supplement_1
- Language
- English
- Version
- Publisher
- ISSN
- 0022-1899
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