Continuous quality improvement interventions to improve long-term outcomes of antiretroviral therapy in women who initiated therapy during pregnancy or breastfeeding in the Democratic Republic of Congo: design of an open-label, parallel, group randomized trial Public Deposited

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Creator
  • Ravelomanana, Noro L R
    • Other Affiliation: Division of Epidemiology, The Ohio State University, College of Public Health, 304 Cunz Hall, 1841 Neil Avenue, Columbus, OH 43210, USA; The University of Kinshasa, School of Public Health, Kinshasa, Democratic Republic of Congo
  • Behets, Frieda
    • Affiliation: Gillings School of Global Public Health, School of Medicine, Department of Social Medicine, Department of Epidemiology
  • Kawende, Bienvenu
    • Other Affiliation: The University of Kinshasa, School of Public Health, Kinshasa, Democratic Republic of Congo
  • Tabala, Martine
    • Other Affiliation: The University of Kinshasa, School of Public Health, Kinshasa, Democratic Republic of Congo
  • Okitolonda, Emile W
    • Other Affiliation: The University of Kinshasa, School of Public Health, Kinshasa, Democratic Republic of Congo
  • Yotebieng, Marcel
    • Other Affiliation: Division of Epidemiology, The Ohio State University, College of Public Health, 304 Cunz Hall, 1841 Neil Avenue, Columbus, OH 43210, USA
Abstract
  • Abstract Background Despite the rapid adoption of the World Health Organization’s 2013 guidelines, children continue to be infected with HIV perinatally because of sub-optimal adherence to the continuum of HIV care in maternal and child health (MCH) clinics. To achieve the UNAIDS goal of eliminating mother-to-child HIV transmission, multiple, adaptive interventions need to be implemented to improve adherence to the HIV continuum. Methods The aim of this open label, parallel, group randomized trial is to evaluate the effectiveness of Continuous Quality Improvement (CQI) interventions implemented at facility and health district levels to improve retention in care and virological suppression through 24 months postpartum among pregnant and breastfeeding women receiving ART in MCH clinics in Kinshasa, Democratic Republic of Congo. Prior to randomization, the current monitoring and evaluation system will be strengthened to enable collection of high quality individual patient-level data necessary for timely indicators production and program outcomes monitoring to inform CQI interventions. Following randomization, in health districts randomized to CQI, quality improvement (QI) teams will be established at the district level and at MCH clinics level. For 18 months, QI teams will be brought together quarterly to identify key bottlenecks in the care delivery system using data from the monitoring system, develop an action plan to address those bottlenecks, and implement the action plan at the level of their district or clinics. Discussion If proven to be effective, CQI as designed here, could be scaled up rapidly in resource-scarce settings to accelerate progress towards the goal of an AIDS free generation. Trial registration The protocol was retrospectively registered on February 7, 2017. ClinicalTrials.gov Identifier: NCT03048669 .
Date of publication
Identifier
  • doi:10.1186/s12913-017-2253-9
Resource type
  • Article
Rights statement
  • In Copyright
Rights holder
  • The Author(s).
Language
  • English
Bibliographic citation
  • BMC Health Services Research. 2017 Apr 26;17(1):306
Publisher
  • BioMed Central
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