Editorial: Omics Research for Pediatric Dentistry in Health and Disease

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  • Ribeiro, Apoena de Aguiar
    • Affiliation: School of Dentistry
  • Modesto Vieira, Adriana
    • Other Affiliation: University of Pittsburgh
  • Portela, Maristela Barbosa
    • Other Affiliation: University of Pittsburgh
  • Jones, Robert S.
    • Other Affiliation: University of Minnesota
Abstract
  • Multi-omics research holds great promise to fill our understanding of pediatric oral health and disease in a concerted manner, ranging from the provision of diagnosis, monitoring, and personalized medicine to the identification of prognostic biomarkers and novel therapeutic targets. This Research Topic aimed to employ multi-omics research to highlight the current understanding of the relationship between the oral microbiome composition, activity and interactions, and children’s oral and systemic health. This knowledge, combining human genome analysis, oral microbiota omics investigation and conditions in health and disease, will provide valuable information on the functional and metabolic changes in diverse pathological states, as well as the identification of molecular signatures, which could lead to precise therapies considering person-centered care in dentistry and medicine. The articles included in this collection show evidence of the potential predictive relationship between the oralmicrobiota, biofilmand childhood diseases, suggesting that the oralmicrobiome can be used as a target for disease diagnosis and novel approaches to maintain children’s health.
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  • Article
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  • In Copyright
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  • Attribution 4.0 International
Journal title
  • Frontiers in Dental Medicine
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  • 3
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  • English
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  • Publisher
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  • 2673-4915

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