Add Health Wave IV Documentation: Candidate Genes Public Deposited

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Creator
  • Tabor, Joyce W.
    • Affiliation: Carolina Population Center
  • Cuthbertson, Carmen C.
    • Affiliation: Gillings School of Global Public Health, Department of Epidemiology
  • Hussey, Jon
    • Affiliation: Gillings School of Global Public Health, Department of Maternal and Child Health
  • Halpern, Carolyn
    • Affiliation: Gillings School of Global Public Health, Department of Maternal and Child Health
  • Whitsel, Eric
    • Affiliation: Gillings School of Global Public Health, School of Medicine, Division of Cardiology, Department of Medicine, Department of Epidemiology
  • Killeya-Jones, Ley A
    • Affiliation: School of Medicine, Department of Radiology
  • Harris, Kathleen Mullan
    • Affiliation: College of Arts and Sciences, Department of Sociology
  • Smolen, Andrew
    • ORCID: https://orcid.org/0000-0002-9030-0562
    • Other Affiliation: University of Colorado Boulder Behavioral Genetics
Abstract
  • During Wave IV, Add Health collected biological specimens from a large, nationally representative sample of young adults. Given the size of the Wave IV sample, its geographic distribution, and in-home setting of the respondent interviews, biological specimen collection involved practical, relatively non-invasive, cost-efficient and innovative methods. These methods included collection of saliva by trained and certified field interviewers, salivary buccal cell lysis and DNA stabilization in the field, then shipment to a central lab for DNA extraction, genotyping, and archiving. The collection of saliva followed the interview and collection of cardiovascular and anthropometric measures (Entzel et al. 2009). It preceded the collection of capillary whole blood (Whitsel et al. 2012) and data on respondent use of prescription and select over-the-counter medications (Tabor et al. 2010). Further details on the design of Add Health Waves I-IV are available elsewhere (Harris 2012; Harris et al. in press).
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Resource type
  • Report
Rights statement
  • In Copyright
Language
  • English
Digital collection
  • National Longitudinal Study of Adolescent to Adult Health (Add Health)
Extent
  • 17 pp
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