Variability in objective and subjective measures affects baseline values in studies of patients with COPD

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  • Anderson, Wayne H.
    • Affiliation: School of Medicine, Marsico Lung Institute/UNC Cystic Fibrosis Center
  • Ha, Jae Wook
    • Affiliation: Gillings School of Global Public Health, Department of Biostatistics
  • Couper, David J.
    • Affiliation: Gillings School of Global Public Health, Department of Biostatistics
  • O’Neal, Wanda K.
    • Affiliation: School of Medicine, Department of Medicine
  • Barr, R. Graham
    • Other Affiliation: Department of Medicine; Columbia University Medical Center
  • Bleecker, Eugene R.
    • Other Affiliation: Center for Genomics and Personalized Medicine Research; Wake Forest School of Medicine
  • Carretta, Elizabeth E.
    • Affiliation: Gillings School of Global Public Health, Department of Biostatistics
  • Cooper, Christopher B.
    • Other Affiliation: David Geffen School of Medicine; University of California
  • Doerschuk, Claire M.
    • Affiliation: School of Medicine, Marsico Lung Institute/UNC Cystic Fibrosis Center
    • Other Affiliation: Department of Medicine
  • Drummond, M Bradley
    • Affiliation: School of Medicine, Marsico Lung Institute/UNC Cystic Fibrosis Center
  • Han, MeiLan K.
    • Other Affiliation: Division of Pulmonary and Critical Care Medicine; University of Michigan Health System
  • Hansel, Nadia N.
    • Other Affiliation: Division of Pulmonary and Critical Care Medicine; Johns Hopkins University School of Medicine
  • Kim, Victor
    • Other Affiliation: Department of Thoracic Medicine and Surgery; Temple University School of Medicine
  • Kleerup, Eric C.
    • Other Affiliation: Division of Pulmonary and Critical Care Medicine; Department of Medicine; David Geffen School of Medicine; University of California Los Angeles
  • Martinez, Fernando J.
    • Other Affiliation: Department of Medicine; Weill Cornell Medical College; New York-Presbyterian Hospital/Weill Cornell Medical Center
  • Rennard, Stephen I.
    • Other Affiliation: Early Clinical Development; Innovative Medicines; AstraZeneca
  • Tashkin, Donald
    • Other Affiliation: Division of Pulmonary and Critical Care Medicine; Department of Medicine; David Geffen School of Medicine; University of California Los Angeles
  • Woodruff, Prescott G.
    • Other Affiliation: Division of Pulmonary; Critical Care; Sleep and Allergy; Department of Medicine; Cardiovascular Research Institute; University of California San Francisco; School of Medicine
  • Paine, Robert
    • Other Affiliation: Department of Internal Medicine; Division of Pulmonary and Critical Care Medicine; Department of Veterans Affairs Medical Center; University of Utah
  • Curtis, Jeffrey L.
    • Other Affiliation: VA Ann Arbor Healthcare System
  • Kanner, Richard E.
    • Other Affiliation: Department of Internal Medicine; Division of Pulmonary and Critical Care Medicine; Department of Veterans Affairs Medical Center; University of Utah
Abstract
  • Understanding the reliability and repeatability of clinical measurements used in the diagnosis, treatment and monitoring of disease progression is of critical importance across all disciplines of clinical practice and in clinical trials to assess therapeutic efficacy and safety.
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  • Article
Rights statement
  • In Copyright
Journal title
  • PloS One
Journal volume
  • 12
Journal issue
  • 9
Page start
  • e0184606
Language
  • English
ISSN
  • 1932-6203

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