Investigate the origins of COVID-19

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  • Bloom, J.D.
    • Other Affiliation: Fred Hutchinson Cancer Research Center
  • Chan, Y.A.
    • Other Affiliation: Harvard University
  • Baric, R.S.
    • Affiliation: Gillings School of Global Public Health, Department of Epidemiology
  • Bjorkman, P.J.
    • Other Affiliation: California Institute of Technology
  • Cobey, S.
    • Other Affiliation: University of Chicago
  • Deverman, B.E.
    • Other Affiliation: Harvard University
  • Fisman, D.N.
    • Other Affiliation: University of Toronto
  • Gupta, R.
    • Other Affiliation: Cambridge Institute of Therapeutic Immunology and Infectious Disease
  • Iwasaki, A.
    • Other Affiliation: Yale University School of Medicine
  • Lipsitch, M.
    • Other Affiliation: Harvard T. H. Chan School of Public Health
  • Medzhitov, R.
    • Other Affiliation: Yale University School of Medicine
  • Neher, R.A.
    • Other Affiliation: University of Basel
  • Nielsen, R.
    • Other Affiliation: University of California, Berkeley
  • Patterson, N.
    • Other Affiliation: Harvard University
  • Stearns, T.
    • Other Affiliation: Stanford University
  • van Nimwegen, E.
    • Other Affiliation: University of Basel
  • Worobey, M.
    • Other Affiliation: University of Arizona
  • Relman, D.A.
    • Other Affiliation: Stanford University
Abstract
  • On 30 December 2019, the Program for Monitoring Emerging Diseases notified the world about a pneumonia of unknown cause in Wuhan, China. Since then, scientists have made remarkable progress in understanding the causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), its transmission, pathogenesis, and mitigation by vaccines, therapeutics, and non-pharmaceutical interventions. Yet more investigation is still needed to determine the origin of the pandemic. Theories of accidental release from a lab and zoonotic spillover both remain viable. Knowing how COVID-19 emerged is critical for informing global strategies to mitigate the risk of future outbreaks.
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  • Article
Rights statement
  • In Copyright
Journal title
  • Science
Journal volume
  • 372
Journal issue
  • 6543
Page start
  • 694
ISSN
  • 0036-8075
Publisher
  • American Association for the Advancement of Science

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