Stages of syphilis in South China – a multilevel analysis of early diagnosis
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Wong, Ngai S, et al. Stages of Syphilis In South China – a Multilevel Analysis of Early Diagnosis. BioMed Central, 2017. https://doi.org/10.17615/8apb-4152APA
Wong, N., Huang, S., Zheng, H., Chen, L., Zhao, P., Tucker, J., Yang, L., Goh, B., & Yang, B. (2017). Stages of syphilis in South China – a multilevel analysis of early diagnosis. BioMed Central. https://doi.org/10.17615/8apb-4152Chicago
Wong, Ngai S, Shujie Huang, Heping Zheng, Lei Chen, Peizhen Zhao, Joseph Tucker, Li G Yang et al. 2017. Stages of Syphilis In South China – a Multilevel Analysis of Early Diagnosis. BioMed Central. https://doi.org/10.17615/8apb-4152- Creator
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Wong, Ngai S
- Affiliation: School of Medicine, Institute for Global Health and Infectious Diseases
- Other Affiliation: University of North Carolina Project-China, Guangzhou, China
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Huang, Shujie
- Other Affiliation: Guangdong Provincial Center for Skin Diseases and STI Control, Guangzhou, China
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Zheng, Heping
- Other Affiliation: Guangdong Provincial Center for Skin Diseases and STI Control, Guangzhou, China
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Chen, Lei
- Other Affiliation: Guangdong Provincial Center for Skin Diseases and STI Control, Guangzhou, China
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Zhao, Peizhen
- Other Affiliation: Guangdong Provincial Center for Skin Diseases and STI Control, Guangzhou, China
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Tucker, Joseph
- Affiliation: School of Medicine, Institute for Global Health and Infectious Diseases
- Other Affiliation: University of North Carolina Project-China, Guangzhou, China
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Yang, Li G
- Other Affiliation: Guangdong Provincial Center for Skin Diseases and STI Control, Guangzhou, China
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Goh, Beng T
- Other Affiliation: Guangdong Provincial Center for Skin Diseases and STI Control, Guangzhou, China; Royal London Hospital, London, UK
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Yang, Bin
- Other Affiliation: Guangdong Provincial Center for Skin Diseases and STI Control, Guangzhou, China
- Abstract
- Abstract Background Early diagnosis of syphilis and timely treatment can effectively reduce ongoing syphilis transmission and morbidity. We examined the factors associated with the early diagnosis of syphilis to inform syphilis screening strategic planning. Methods In an observational study, we analyzed reported syphilis cases in Guangdong Province, China (from 2014 to mid-2015) accessed from the national case-based surveillance system. We categorized primary and secondary syphilis cases as early diagnosis and categorized latent and tertiary syphilis as delayed diagnosis. Univariate analyses and multivariable logistic regressions were performed to identify the factors associated with early diagnosis. We also examined the factors associated with early diagnosis at the individual and city levels in multilevel logistic regression models with cases nested by city (n = 21), adjusted for age at diagnosis and gender. Results Among 83,944 diagnosed syphilis cases, 22% were early diagnoses. The city-level early diagnosis rate ranged from 7 to 46%, consistent with substantial geographic variation as shown in the multilevel model. Early diagnosis was associated with cases presenting to specialist clinics for screening, being male and attaining higher education level. Cases received syphilis testing in institutions and hospitals, and diagnosed in hospitals were less likely to be in early diagnosis. At the city-level, cases living in a city equipped with more hospitals per capita were less likely to be early diagnosis. Conclusions To enhance early diagnosis of syphilis, city-specific syphilis screening strategies with a mix of passive and client/provider-initiated testing might be a useful approach.
- Date of publication
- January 31, 2017
- DOI
- Identifier
- Resource type
- Article
- Rights statement
- In Copyright
- Rights holder
- The Author(s).
- Language
- English
- Bibliographic citation
- BMC Public Health. 2017 Jan 31;17(1):135
- Publisher
- BioMed Central
- Date uploaded
- February 3, 2017
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