Household factors and the risk of severe COVID-like illness early in the U.S. pandemic

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  • Nash, Denis
    • Other Affiliation: City University of New York
  • Qasmieh, Saba
    • Other Affiliation: City University of New York
  • Robertson, McKaylee
    • Other Affiliation: City University of New York
  • Rane, Madhura
    • Other Affiliation: City University of New York
  • Zimba, Rebecca
    • Other Affiliation: City University of New York
  • Kulkarni, Sarah G.
    • Other Affiliation: City University of New York
  • Berry, Amanda
    • Other Affiliation: City University of New York
  • You, William
    • Other Affiliation: City University of New York
  • Mirzayi, Chloe
    • Other Affiliation: City University of New York
  • Westmoreland, Drew
    • Other Affiliation: City University of New York
  • Parcesepe, Angela
    • Affiliation: Gillings School of Global Public Health, Department of Maternal and Child Health
  • Waldron, Levi
    • Other Affiliation: City University of New York
  • Kochhar, Shivani
    • Other Affiliation: City University of New York
  • Maroko, Andrew R.
    • Other Affiliation: City University of New York
  • Grov, Christian
    • Other Affiliation: City University of New York
  • CHASING COVID Cohort Study Team
Abstract
  • Objective To investigate the role of children in the home and household crowding as risk factors for severe COVID-19 disease. Methods We used interview data from 6,831 U.S. adults screened for the Communities, Households and SARS/CoV-2 Epidemiology (CHASING) COVID Cohort Study in April 2020. Results In logistic regression models, the adjusted odds ratio [aOR] of hospitalization due to COVID-19 for having (versus not having) children in the home was 10.5 (95% CI:5.7–19.1) among study participants living in multi-unit dwellings and 2.2 (95% CI:1.2–6.5) among those living in single unit dwellings. Among participants living in multi-unit dwellings, the aOR for COVID-19 hospitalization among participants with more than 4 persons in their household (versus 1 person) was 2.5 (95% CI:1.0–6.1), and 0.8 (95% CI:0.15–4.1) among those living in single unit dwellings. Conclusion Early in the US SARS-CoV-2 pandemic, certain household exposures likely increased the risk of both SARS-CoV-2 acquisition and the risk of severe COVID-19 disease.
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  • Article
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  • In Copyright
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  • Attribution 4.0 International
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  • PLOS ONE
Journal volume
  • 17
Journal issue
  • 7
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  • e0271786
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  • English
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ISSN
  • 1932-6203

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