Urinary incontinence and health-related quality of life among older Americans with and without cancer: a cross-sectional study Public Deposited

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Creator
  • Stover, Angela M
    • Affiliation: Gillings School of Global Public Health, N.C. Cancer Hospital, UNC Lineberger Comprehensive Cancer Center, Department of Health Behavior, School of Medicine
  • Chen, Ronald
    • Affiliation: School of Medicine, Department of Radiation Oncology, N.C. Cancer Hospital, UNC Lineberger Comprehensive Cancer Center
  • Reeve, Bryce
    • Affiliation: Gillings School of Global Public Health, Department of Health Policy and Management, N.C. Cancer Hospital, UNC Lineberger Comprehensive Cancer Center, School of Medicine
  • White, Alexandra J
    • Affiliation: Gillings School of Global Public Health, Department of Epidemiology
  • Irwin, Debra E
    • Affiliation: Gillings School of Global Public Health, Department of Epidemiology, N.C. Cancer Hospital, UNC Lineberger Comprehensive Cancer Center, School of Medicine
Abstract
  • Abstract Background Few studies have investigated the impact of urinary incontinence (UI) on health-related quality of life (HRQOL) among cancer survivors. UI is prevalent in the general population and can be both an indicator of cancer and a side effect of cancer treatment. UI and cancer diagnoses have been associated with decreases in HRQOL. This study evaluates the prevalence of UI and the impact on HRQOL among older cancer survivors. Methods The prevalence of UI among cancer survivors (breast, prostate, bladder, colorectal, lung, and endometrial/uterine cancers) and those without cancer was estimated using the SEER-MHOS database. Factors associated with UI were investigated using logistic regression and the impact of UI on SF-36 scores was determined using linear regression. Results Over 36% of SEER-MHOS beneficiaries without cancer reported UI and higher prevalence was noted among cancer survivors (37%-54% depending on cancer type). History of bladder, breast, endometrial/uterine, or prostate cancer was associated with higher prevalence of UI. UI was independently associated with both lower physical component scores (PCS) (−1.27; 95%CI:-1.34,-1.20) and mental component scores (MCS) (−1.75; 95%CI −1.83, -1.68). A suggested decreasing trend in the prevalence of UI was associated with a longer time since cancer diagnosis. Conclusions UI was highly prevalent, especially in bladder, endometrial/uterine, and prostate cancer survivors. Improved recognition of UI risk among cancer survivors will help clinicians better anticipate and mediate the effect of UI on individuals’ HRQOL.
Date of publication
Identifier
  • doi:10.1186/1471-2407-13-377
  • 23924272
Resource type
  • Article
Rights statement
  • In Copyright
Rights holder
  • Alexandra J White et al.; licensee BioMed Central Ltd.
License
Journal title
  • BMC Cancer
Journal volume
  • 13
Journal issue
  • 1
Page start
  • 377
Language
  • English
Is the article or chapter peer-reviewed?
  • Yes
ISSN
  • 1471-2407
Bibliographic citation
  • BMC Cancer. 2013 Aug 07;13(1):377
Access
  • Open Access
Publisher
  • BioMed Central Ltd
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