Microbial influences on the small intestinal response to radiation injury Public Deposited

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Creator
  • Packey, Christopher D
  • Ciorba, Matthew A
Abstract
  • Injury to the small bowel from ionizing radiation occurs commonly in patients undergoing cancer therapy and less commonly in instances of accidental radiation overexposure. Several lines of evidence now suggest that dynamic interactions between the host’s enteric microbiota and innate immune system are important in modulating the intestinal response to radiation. Here, we will review recent developments in the area of acute radiation enteropathy and examine the current state of knowledge regarding the impact of host–microbial interactions in the process.
Date of publication
Keyword
DOI
Identifier
Resource type
  • Article
Rights statement
  • In Copyright
Journal title
  • Current Opinion in Gastroenterology
Journal volume
  • 26
Journal issue
  • 2
Page start
  • 88
Page end
  • 94
Language
  • English
ISSN
  • 1531-7056
  • 0267-1379
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