Problems in CSF and Ophthalmic Disease Research

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  • Machiele, Ryan
    • Affiliation: School of Medicine, Department of Ophthalmology
  • Frankfort, Benjamin Jay
    • Other Affiliation: Baylor College of Medicine
  • Killer, Hanspeter Esriel
    • Other Affiliation: University of Basel
  • Fleischman, David
    • Affiliation: School of Medicine, Department of Ophthalmology
Abstract
  • There has been significant interest and progress in the understanding of cerebrospinal fluid pressure and its relationship to glaucoma and other ophthalmic diseases. However, just as every physiologic fluid pressure fluctuates, cerebrospinal fluid pressure (CSFP) is similarly dynamic. Coupling this with the difficulty in measuring the pressure, there are many obstacles in furthering this field of study. This review highlights some of the difficulties in CSFP research, including fluid compartmentalization, estimation equations, and pressure fluctuation. Keeping these limitations in mind will hopefully improve the quality and context of this burgeoning field.
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  • Article
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  • In Copyright
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  • Attribution 4.0 International
Journal title
  • Frontiers in Ophthalmology
Journal volume
  • 2
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  • English
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  • Publisher
ISSN
  • 2674-0826

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