Neurocognitive functions and social functioning in young females with recent-onset anorexia nervosa and recovered individuals Public Deposited

Downloadable Content

Download PDF
Creator
  • Plessen, Kerstin J
    • Other Affiliation: Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Bispebjerg Bakke 30, 2400 København NV, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
  • Kjaersdam Telléus, Gry
    • Other Affiliation: Unit for Psychiatric Research, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Faculty of Medicine, Aalborg University, Aalborg, Denmark
  • Bulik, Cynthia
    • Affiliation: Gillings School of Global Public Health, Department of Nutrition, School of Medicine, Department of Psychiatry
  • Bentz, Mette
    • Other Affiliation: Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Bispebjerg Bakke 30, 2400 København NV, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
  • Pedersen, Tine
    • Other Affiliation: Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Bispebjerg Bakke 30, 2400 København NV, Denmark; Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark
  • Jepsen, Jens R M
    • Other Affiliation: Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Bispebjerg Bakke 30, 2400 København NV, Denmark; Lundbeck Foundation Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS) and Center for Neuropsychiatric Schizophrenia Research (CNSR), Psychiatric Center Glostrup, Glostrup, Denmark
  • Moslet, Ulla
    • Other Affiliation: Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Bispebjerg Bakke 30, 2400 København NV, Denmark
Abstract
  • Abstract Background Young individuals with anorexia nervosa (AN) or recovered from AN display impairments of social function. To date, however, it is not clear whether they differ from controls with respect to neurocognitive performance and whether those functions contribute to the compromised social function observed in individuals with AN. Methods We included 43 young females with first-episode AN, 28 individuals recovered from adolescent-onset AN, and 41 control individuals (14–22 yr), all without comorbid autism spectrum disorder. We compared the performance of participants across groups in seven neurocognitive functions relevant to social functioning: set-shifting, local processing, processing speed, working memory, sustained attention, verbal memory, and verbal abstraction. Further, we tested the association between neurocognitive function and social function, measured by Autism Diagnostic Observation Schedule (ADOS), with an ordinal logistic regression model. Results First, participants did not differ on any neurocognitive function across groups. Second, only the neurocognitive function “verbal memory” was significantly associated with social function. Higher performance in verbal memory was associated with lower odds of impaired social function. Diagnostic group remained a significant factor, but the absence of an interaction between group and neurocognitive performance indicated that the association between verbal memory and social function was independent of group membership. Conclusion Young individuals with AN and those recovered from AN did not differ from controls with respect to neurocognitive performance. Verbal memory was associated with social function in all groups.
Date of publication
Identifier
  • doi:10.1186/s40337-017-0137-3
Resource type
  • Article
Rights statement
  • In Copyright
Rights holder
  • The Author(s).
Language
  • English
Bibliographic citation
  • Journal of Eating Disorders. 2017 Feb 27;5(1):5
Publisher
  • BioMed Central
Parents:

This work has no parents.

Items