Vitamin E, γ-tocopherol, reduces airway neutrophil recruitment after inhaled endotoxin challenge in rats and in healthy volunteers Public Deposited
- Creator
- Hernandez, Michelle L.
- Wagner, James G.
- Kala, Aline
- Mills, Katherine
- Wells, Heather B.
- Alexis, Neil E.
- Lay, John C.
- Jiang, Qing
- Zhang, Hongtao
- Zhou, Haibo
- Peden, David B.
- Abstract
- Epidemiologic studies suggest that dietary vitamin E is an important candidate intervention for asthma. Our group has shown that daily consumption of vitamin E (gamma tocopherol, γT) has anti-inflammatory actions in both rodent and human phase I studies. The objective of this study was to test whether γT supplementation could mitigate a model of neutrophilic airway inflammation in rats and in healthy human volunteers.
- Date of publication
- 2013
- Keyword
- DOI
- Identifier
- PMCID: PMC3654053
- Onescience id: abe5da376b2303a4dfe8e3ce5db0ffe58d89968c
- PMID: 23402870
- Publisher DOI: https://doi.org/10.1016/j.freeradbiomed.2013.02.001
- Resource type
- Article
- Rights statement
- In Copyright
- Journal title
- Free Radical Biology and Medicine
- Journal volume
- 60
- Page start
- 56
- Page end
- 62
- Language
- English
- ISSN
- 1873-4596
- 0891-5849
- Parents:
This work has no parents.
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