Animal models for COVID-19
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Muñoz Fontela, C, et al. Animal Models for Covid-19. 2020. https://doi.org/10.17615/828n-q073APA
Muñoz Fontela, C., Dowling, W., Funnell, S., Gsell, P., Riveros Balta, A., Albrecht, R., Andersen, H., Baric, R., Carroll, M., Cavaleri, M., Qin, C., Crozier, I., Dallmeier, K., De Waal, L., De Wit, E., Delang, L., Dohm, E., Duprex, W., Falzarano, D., Finch, C., Frieman, M., Graham, B., Gralinski, L., Guilfoyle, K., Haagmans, B., Hamilton, G., Hartman, A., Herfst, S., Kaptein, S., Klimstra, W., Knezevic, I., Krause, P., Kuhn, J., Le Grand, R., Lewis, M., Liu, W., Maisonnasse, P., Mc Elroy, A., Munster, V., Oreshkova, N., Rasmussen, A., Rocha Pereira, J., Rockx, B., Rodríguez, E., Rogers, T., Salguero, F., Schotsaert, M., Stittelaar, K., Thibaut, H., Tseng, C., Vergara Alert, J., Beer, M., Brasel, T., Chan, J., García Sastre, A., Neyts, J., Perlman, S., Reed, D., Richt, J., Roy, C., Segalés, J., Vasan, S., Henao Restrepo, A., & Barouch, D. (2020). Animal models for COVID-19. https://doi.org/10.17615/828n-q073Chicago
Muñoz Fontela, C., W.E Dowling, S.G.P Funnell, P. S Gsell, A.X Riveros Balta, R.A Albrecht, H Andersen et al. 2020. Animal Models for Covid-19. https://doi.org/10.17615/828n-q073- Creator
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Muñoz-Fontela, C.
- Other Affiliation: Bernhard Nocht Institute for Tropical Medicine
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Dowling, W.E.
- Other Affiliation: Centre for Epidemic Preparedness Innovations (CEPI)
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Funnell, S.G.P.
- Other Affiliation: Public Health England
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Gsell, P.-S.
- Other Affiliation: World Health Organization
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Riveros-Balta, A.X.
- Other Affiliation: World Health Organization
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Albrecht, R.A.
- Other Affiliation: Icahn School of Medicine at Mount Sinai
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Andersen, H.
- Other Affiliation: Bioqual Inc
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Baric, R.S.
- Affiliation: Gillings School of Global Public Health, Department of Epidemiology
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Carroll, M.W.
- Other Affiliation: Public Health England
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Cavaleri, M.
- Other Affiliation: European Medicines Agency
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Qin, C.
- Other Affiliation: Chinese Academy of Medical Sciences
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Crozier, I.
- Other Affiliation: Frederick National Laboratory for Cancer Research
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Dallmeier, K.
- Other Affiliation: KU Leuven
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de Waal, L.
- Other Affiliation: Viroclinics Xplore
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de Wit, E.
- Other Affiliation: National Institutes of Health
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Delang, L.
- Other Affiliation: KU Leuven
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Dohm, E.
- Other Affiliation: University of Alabama at Birmingham
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Duprex, W.P.
- Other Affiliation: University of Pittsburgh
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Falzarano, D.
- Other Affiliation: University of Saskatchewan
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Finch, C.L.
- Other Affiliation: National Institutes of Health
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Frieman, M.B.
- Other Affiliation: University of Maryland School of Medicine
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Graham, B.S.
- Other Affiliation: National Institutes of Health
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Gralinski, L.E.
- Affiliation: Gillings School of Global Public Health, Department of Epidemiology
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Guilfoyle, K.
- Other Affiliation: Viroclinics Xplore
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Haagmans, B.L.
- Other Affiliation: Erasmus University Medical Center
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Hamilton, G.A.
- Other Affiliation: Emulate Inc
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Hartman, A.L.
- Other Affiliation: University of Pittsburgh
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Herfst, S.
- Other Affiliation: Erasmus University Medical Center
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Kaptein, S.J.F.
- Other Affiliation: KU Leuven
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Klimstra, W.B.
- Other Affiliation: University of Pittsburgh
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Knezevic, I.
- Other Affiliation: World Health Organization
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Krause, P.R.
- Other Affiliation: FDA
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Kuhn, J.H.
- Other Affiliation: National Institutes of Health
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Le Grand, R.
- Other Affiliation: Université Paris-Saclay
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Lewis, M.G.
- Other Affiliation: Bioqual Inc
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Liu, W.-C.
- Other Affiliation: Icahn School of Medicine at Mount Sinai
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Maisonnasse, P.
- Other Affiliation: Université Paris-Saclay
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McElroy, A.K.
- Other Affiliation: University of Pittsburgh School of Medicine
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Munster, V.
- Other Affiliation: National Institutes of Health
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Oreshkova, N.
- Other Affiliation: Wageningen University and Research
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Rasmussen, A.L.
- Other Affiliation: Columbia Mailman School of Public Health
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Rocha-Pereira, J.
- Other Affiliation: KU Leuven
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Rockx, B.
- Other Affiliation: Erasmus University Medical Center
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Rodríguez, E.
- Other Affiliation: Bernhard Nocht Institute for Tropical Medicine
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Rogers, T.F.
- Other Affiliation: University of California San Diego
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Salguero, F.J.
- Other Affiliation: Public Health England
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Schotsaert, M.
- Other Affiliation: Icahn School of Medicine at Mount Sinai
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Stittelaar, K.J.
- Other Affiliation: Viroclinics Xplore
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Thibaut, H.J.
- Other Affiliation: KU Leuven
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Tseng, C.-T.
- Other Affiliation: University of Texas Medical Branch
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Vergara-Alert, J.
- Other Affiliation: Campus Universitat Autònoma de Barcelona
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Beer, M.
- Other Affiliation: Friedrich-Loeffler-Institut
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Brasel, T.
- Other Affiliation: University of Texas Medical Branch
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Chan, J.F.W.
- Other Affiliation: The University of Hong Kong
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García-Sastre, A.
- Other Affiliation: Icahn School of Medicine at Mount Sinai
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Neyts, J.
- Other Affiliation: KU Leuven
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Perlman, S.
- Other Affiliation: University of Iowa
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Reed, D.S.
- Other Affiliation: University of Pittsburgh
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Richt, J.A.
- Other Affiliation: Kansas State University
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Roy, C.J.
- Other Affiliation: Tulane National Primate Research Center
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Segalés, J.
- Other Affiliation: Campus Universitat Autònoma de Barcelona
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Vasan, S.S.
- Other Affiliation: Australian Centre for Disease Preparedness
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Henao-Restrepo, A.M.
- Other Affiliation: World Health Organization
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Barouch, D.H.
- Other Affiliation: Harvard Medical School
- Abstract
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the introduction of a novel coronavirus into humans late in 2019 (first detected in Hubei province, China). As of 18 September 2020, SARS-CoV-2 has spread to 215 countries, has infected more than 30 million people and has caused more than 950,000 deaths. As humans do not have pre-existing immunity to SARS-CoV-2, there is an urgent need to develop therapeutic agents and vaccines to mitigate the current pandemic and to prevent the re-emergence of COVID-19. In February 2020, the World Health Organization (WHO) assembled an international panel to develop animal models for COVID-19 to accelerate the testing of vaccines and therapeutic agents. Here we summarize the findings to date and provides relevant information for preclinical testing of vaccine candidates and therapeutic agents for COVID-19.
- Date of publication
- 2020
- Keyword
- DOI
- Identifier
- Resource type
- Article
- Rights statement
- In Copyright
- Journal title
- Nature
- Journal volume
- 586
- Journal issue
- 7830
- Page start
- 509
- Page end
- 515
- ISSN
- 1476-4687
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