Livedoid vasculopathy: A review with focus on terminology and pathogenesis
Public Deposited- Creator
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Eswaran, H.
- Affiliation: School of Medicine, Department of Medicine
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Googe, P.
- Affiliation: School of Medicine, Department of Dermatology
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Vedak, P.
- Affiliation: School of Medicine, Department of Dermatology
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Marston, W.A.
- Affiliation: School of Medicine, Department of Surgery
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Moll, S.
- Affiliation: School of Medicine, Department of Medicine
- Abstract
- Livedoid vasculopathy (LV) is a rare thrombotic vasculopathy of the dermis characterized by painful, relapsing ulcers over the lower extremities. Diagnosis is challenging due to the overlap in clinical appearance and nomenclature with other skin disorders. Treatment selection is complicated by poor understanding of the pathogenesis of LV and lack of robust clinical trials evaluating therapy efficacy. The terminology and pathophysiology of LV are reviewed here, along with its epidemiology, clinical and histologic features, and treatment options. A diagnostic pathway is suggested to guide providers in evaluating for comorbidities, referring to appropriate specialists, and choosing from the available classes of therapy.
- Date of publication
- 2022
- Keyword
- DOI
- Identifier
- Resource type
- Article
- Rights statement
- In Copyright
- License
- Attribution 4.0 International
- Journal title
- Vascular Medicine
- Journal volume
- 27
- Journal issue
- 6
- Page start
- 593
- Page end
- 603
- Language
- English
- Version
- Publisher
- ISSN
- 1358-863X
- Publisher
- SAGE Publications Ltd
Relations
- Parents:
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