Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review Public Deposited

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  • O’Mahony, Liam
    • Other Affiliation: Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland
  • Muraro, Antonella
    • Other Affiliation: Food Allergy Referral Centre Veneto Region, Department of Women and Child Health, Padua General University Hospital, Padua, Italy
  • Beyer, Kirsten
    • Other Affiliation: Pediatric Pneumology and Immunology, Charité Universitätsmedizin, Berlin, Germany; Icahn School of Medicine at Mount Sinai, New York, USA
  • du Toit, George
    • Other Affiliation: Division of Asthma, Allergy and Lung Biology, Department of Paediatric Allergy, MRC and Asthma Centre in Allergic Mechanisms of Asthma, King’s College London and St Thomas NHS Foundation Trust, London, UK
  • Roberts, Graham
    • Other Affiliation: The David Hide Asthma and Allergy Research Centre, St Mary’s Hospital, Newport Isle of Wight, NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Faculty of Medicine, University of Southampton, Southampton, UK
  • van Ree, Ronald
    • Other Affiliation: Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The Netherlands
  • Akdis, Cezmi
    • Other Affiliation: Swiss Institute for Allergy and Asthma Research, Davos, Switzerland
  • Nurmatov, Ulugbek
    • Other Affiliation: Division of Population Medicine Neuadd Meirionnydd, School of Medicine, Cardiff University, Cardiff, UK
  • Papadopoulos, Nikolaos
    • Other Affiliation: Department of Allergy, 2nd Pediatric Clinic, University of Athens, Athens, Greece
  • Timmermans, Frans
    • Other Affiliation: Nederlands Anafylaxis Netwerk - European Anaphylaxis Taskforce, Dordrecht, The Netherlands
  • Eigenmann, Philippe
    • Other Affiliation: University Hospitals of Geneva and Medical School, University of Geneva, Geneva, Switzerland
  • Santos, Alexandra
    • Other Affiliation: Division of Asthma Allergy and Lung Biology, Department of Paediatric Allergy, King’s College London/Guy’s, and St Thomas’ Hospital NHS Foundation Trust, London, UK
  • Bindslev-Jensen, Carsten
    • Other Affiliation: Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark
  • Poulsen, Lars
    • Other Affiliation: Allergy Clinic, Copenhagen University Hospital, Gentofte, Denmark
  • Fernandez-Rivas, Montserrat
    • Other Affiliation: Allergy Department, Hospital Clínico San Carlos, IdISSC, Madrid, Spain
  • Burks, Wesley
    • Affiliation: School of Medicine, Department of Pediatrics
  • Makela, Mika
    • Other Affiliation: Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland
  • Ebisawa, Motohiro
    • Other Affiliation: Department of Allergy, Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, Sagamihara, Japan
  • Knol, Edward
    • Other Affiliation: Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
  • Sheikh, Aziz
    • Other Affiliation: Allergy and Respiratory Research Group, The University of Edinburgh, Edinburgh, UK
  • Pajno, Giovanni B
    • Other Affiliation: Allergy Unit, Department of Pediatric, University of Messina, Messina, Italy
  • Sampson, Hugh
    • Other Affiliation: World Allergy Organization (WAO), Milwaukee, USA
  • Nadeau, Kari C
    • Other Affiliation: Division of Immunology, Allergy and Rheumatology, Department of Pediatrics, Stanford University, Stanford, USA
  • Alvaro-Lozano, Montserrat
    • Other Affiliation: Paediatric Allergy and Clinical Immunology Section, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain
  • Dhami, Sangeeta
    • Other Affiliation: Evidence-Based Health Care Ltd, Edinburgh, UK
  • Sackesen, Cansin
    • Other Affiliation: Koç University Hospital, Istanbul, Turkey
  • Abstract Background The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy. Methods We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. Discussion The findings from this review will be used to inform the development of recommendations for EAACI’s Guidelines on AIT.
Date of publication
  • doi:10.1186/s13601-016-0113-z
Resource type
  • Article
Rights statement
  • In Copyright
Rights holder
  • Dhami et al
  • English
Bibliographic citation
  • Clinical and Translational Allergy. 2016 Jul 05;6(1):24
  • BioMed Central

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