Therapeutic Index Estimation of Antiepileptic Drugs: A Systematic Literature Review Approach

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Creator
  • Greenberg, Rachel G.
    • Other Affiliation: Duke Clinical Research Institute
  • Melloni, Chiara
    • Other Affiliation: Duke Clinical Research Institute
  • Wu, Huali
    • Other Affiliation: Duke Clinical Research Institute
  • Gonzalez, Daniel
    • Eshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics
    • Other Affiliation: Office of Generic Drugs; US Food and Drug Administration
  • Ku, Lawrence
    • Other Affiliation: Duke Clinical Research Institute
  • Hill, Kevin D.
    • Other Affiliation: Duke Clinical Research Institute
  • Hornik, Christoph P.
    • Other Affiliation: Duke Clinical Research Institute
  • Cohen-Wolkowiez, Michael
    • Other Affiliation: Duke Clinical Research Institute
  • Guptill, Jeffrey T.
    • Other Affiliation: Duke Clinical Research Institute
Abstract
  • To determine whether data obtained from the medical literature can be used to estimate the therapeutic index of 5 antiepileptic drugs (AEDs): carbamazepine, lamotrigine, phenobarbital, phenytoin, and valproate.
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  • Article
Rights statement
  • In Copyright
Journal title
  • Clinical Neuropharmacology
Journal volume
  • 39
Journal issue
  • 5
Page start
  • 232
Page end
  • 240
Language
  • English
ISSN
  • 1537-162X
  • 0362-5664

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