Combined CD4 T-Cell and Antibody Response to Human Minor Histocompatibility Antigen DBY After Allogeneic Stem-Cell Transplantation Public Deposited
- Creator
- Porcheray, Fabrice
- Miklos, David B.
- Floyd, Blair H.
- Sarantopoulos, Stefanie
- Bellucci, Roberto
- Soiffer, Robert J.
- Antin, Joseph H.
- Alyea, Edwin P.
- Ritz, Jerome
- Zorn, Emmanuel
- Abstract
- Antibody responses to HY antigens in male recipients are frequent after transplantation of stem cells from female donors (Miklos et al., Blood 2005; 105: 2973; Miklos et al., Blood 2004; 103: 353). However, evidence that this B-cell immunity is accompanied by T-cell responses to the cognate antigens is scarce. Here, we examined T- and B-cell responses to DBY antigen in a male patient who received hematopoietic stem cells from a human leukocyte antigen-identical female sibling.
- Date of publication
- 2011
- Keyword
- Sistema histocompatibilidad menor
- Homogreffe
- Immune response
- Lymphocyte T CD4
- Stem cell
- Célula primitiva
- Hombre
- Homme
- Anticorps
- Célula hematopoyética
- Greffe
- Cellule hématopoïétique
- Cellule souche
- Homograft
- Injerto
- Immunité cellulaire
- Hematopoietic cell
- Graft
- Human
- CD4 T lymphocyte
- Réponse immune
- Cellular immunity
- Antibody
- Système histocompatibilité mineur
- Minor histocompatibility system
- DOI
- Identifier
- Onescience id: 45e759c7c0260eff361d5845c97d6223ec886b7e
- PMCID: PMC3263512
- Publisher DOI: https://doi.org/10.1097/TP.0b013e3182244cc3
- PMID: 21709606
- Resource type
- Article
- Rights statement
- In Copyright
- Journal title
- Transplantation
- Journal volume
- 92
- Journal issue
- 3
- Page start
- 359
- Page end
- 365
- Language
- English
- ISSN
- 0041-1337
- 1534-6080
- Parents:
This work has no parents.
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