Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden

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Creator
  • Daghestani, Hikmat N.
    • Other Affiliation: Duke Molecular Physiology Institute; Duke University; School of Medicine
  • Jordan, Joanne M.
    • Affiliation: School of Medicine, Thurston Arthritis Research Center
  • Renner, Jordan B.
    • Affiliation: School of Medicine, Department of Radiology
  • Doherty, Michael
    • Other Affiliation: Department of Academic Rheumatology; University of Nottingham
  • Gerry Wilson,
    • Other Affiliation: Conway Institute for Biomolecuar; Biomedical Research University College Dublin
  • Kraus, Virginia B.
    • Other Affiliation: Duke Molecular Physiology Institute; Duke University; School of Medicine
Abstract
  • Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum levels of type IIA procollagen amino terminal propeptide (sPIIANP), a biomarker representing type II collagen synthesis, in osteoarthritis.
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  • Article
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  • In Copyright
Journal title
  • PloS One
Journal volume
  • 12
Journal issue
  • 12
Page start
  • e0190251
Language
  • English
ISSN
  • 1932-6203

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