2014 Evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8)
Public DepositedAdd to collection
You do not have access to any existing collections. You may create a new collection.
Downloadable Content
Download PDFCitation
MLA
James, Paul A, et al. 2014 Evidence-based Guideline for the Management of High Blood Pressure In Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (jnc 8). 2014. https://doi.org/10.17615/161s-v683APA
James, P., Oparil, S., Carter, B., Cushman, W., Dennison Himmelfarb, C., Handler, J., Lackland, D., Le Fevre, M., Mac Kenzie, T., Ogedegbe, O., Smith, J., Svetkey, L., Taler, S., Townsend, R., Wright, J., Narva, A., & Ortiz, E. (2014). 2014 Evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). https://doi.org/10.17615/161s-v683Chicago
James, Paul A., Suzanne Oparil, Barry L Carter, William C Cushman, Cheryl Dennison Himmelfarb, Joel Handler, Daniel T Lackland et al. 2014. 2014 Evidence-Based Guideline for the Management of High Blood Pressure In Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (jnc 8). https://doi.org/10.17615/161s-v683- Creator
-
James, Paul A.
- Other Affiliation: University of Iowa, Iowa City
-
Oparil, Suzanne
- Other Affiliation: University of Alabama at Birmingham School of Medicine
-
Carter, Barry L.
- Other Affiliation: University of Iowa, Iowa City
-
Cushman, William C.
- Other Affiliation: Memphis Veterans Affairs Medical Center and the University of Tennessee, Memphis
-
Dennison-Himmelfarb, Cheryl
- Other Affiliation: Johns Hopkins University School of Nursing, Baltimore, Maryland
-
Handler, Joel
- Other Affiliation: Kaiser Permanente, Anaheim, California
-
Lackland, Daniel T.
- Other Affiliation: Medical University of South Carolina, Charleston
-
LeFevre, Michael L.
- Other Affiliation: University of Missouri, Columbia
-
MacKenzie, Thomas D.
- Other Affiliation: Denver Health and Hospital Authority and the University of Colorado School of Medicine, Denver
-
Ogedegbe, Olugbenga
- Other Affiliation: New York University School of Medicine, New York, New York
-
Smith, Sidney C., Jr.
- Affiliation: School of Medicine, Department of Medicine
-
Svetkey, Laura P.
- Other Affiliation: Duke University, Durham, North Carolina
-
Taler, Sandra J.
- Other Affiliation: Mayo Clinic College of Medicine, Rochester, Minnesota
-
Townsend, Raymond R.
- Other Affiliation: University of Pennsylvania, Philadelphia
-
Wright, Jackson T., Jr.
- Other Affiliation: Case Western Reserve University, Cleveland, Ohio
-
Narva, Andrew S.
- Other Affiliation: National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
-
Ortiz, Eduardo
- Other Affiliation: National Heart, Lung, and Blood Institute, Bethesda, Maryland
- Abstract
- "Hypertension is the most common condition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if not detected early and treated appropriately. Patients want to be assured that blood pressure (BP) treatment will reduce their disease burden, while clinicians want guidance on hypertension management using the best scientific evidence. This report takes a rigorous, evidence-based approach to recommend treatment thresholds, goals, and medications in the management of hypertension in adults. Evidence was drawn from randomized controlled trials, which represent the gold standard for determining efficacy and effectiveness. Evidence quality and recommendations were graded based on their effect on important outcomes. There is strong evidence to support treating hypertensive persons aged 60 years or older to a BP goal of less than 150/90 mm Hg and hypertensive persons 30 through 59 years of age to a diastolic goal of less than 90 mm Hg; however, there is insufficient evidence in hypertensive persons younger than 60 years for a systolic goal, or in those younger than 30 years for a diastolic goal, so the panel recommends a BP of less than 140/90 mm Hg for those groups based on expert opinion. The same thresholds and goals are recommended for hypertensive adults with diabetes or nondiabetic chronic kidney disease (CKD) as for the general hypertensive population younger than 60 years. There is moderate evidence to support initiating drug treatment with an angiotensin-converting enzyme inhibitor, angiotensin receptor blocker, calcium channel blocker, or thiazide-type diuretic in the nonblack hypertensive population, including those with diabetes. In the black hypertensive population, including those with diabetes, a calcium channel blocker or thiazide-type diuretic is recommended as initial therapy. There is moderate evidence to support initial or add-on antihypertensive therapy with an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in persons with CKD to improve kidney outcomes. Although this guideline provides evidence-based recommendations for the management of high BP and should meet the clinical needs of most patients, these recommendations are not a substitute for clinical judgment, and decisions about care must carefully consider and incorporate the clinical characteristics and circumstances of each individual patient."
- Date of publication
- 2014
- Keyword
- DOI
- Identifier
- 2-s2.0-84893549987
- https://doi.org/10.1001/jama.2013.284427
- Related resource URL
- Resource type
- Journal Item
- Rights statement
- In Copyright
- Journal title
- JAMA - Journal of the American Medical Association
- Journal volume
- 311
- Journal issue
- 5
- Page start
- 507
- Page end
- 520
- Language
- English
- Version
- Postprint
- ISSN
- 0098-7484
Relations
- Parents:
This work has no parents.
Items
Thumbnail | Title | Date Uploaded | Visibility | Actions |
---|---|---|---|---|
2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults.pdf | 2019-05-03 | Public | Download |