Effects of Thyrotropin-Releasing Hormone in Depression Public Deposited

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Abstract
  • Ten euthyroid women with unipolar depression were treated with a single injection of thyrotropin-releasing hormone (T.R.H.) and a single injection of saline in a double-blind, crossover comparison. T.R.H. caused a prompt, brief improvement in depression without causing significant side-effects Most patients showed a reduced thyrotropin (T.S.H.) response to T.R.H. injection, though none had abnormal thyroid function tests or clinical findings suggesting pituitary or thyroid disease.
Date of publication
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Resource type
  • Article
Rights statement
  • In Copyright
Journal title
  • The Lancet
Journal volume
  • 300
Journal issue
  • 7785
Page start
  • 999
Page end
  • 1002
Language
  • English
Version
  • Postprint
ISSN
  • 0140-6736
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