Independent associations of childhood and current socioeconomic status with risk of self-reported doctor-diagnosed arthritis in a family-medicine cohort of North-Carolinians Public Deposited

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Creator
  • Callahan, Leigh
    • Affiliation: School of Medicine, Department of Social Medicine, Thurston Arthritis Research Center, Department of Medicine
  • Baldassari, Antoine R
    • Affiliation: School of Medicine, Thurston Arthritis Research Center
  • Cleveland, Rebecca J
    • Affiliation: School of Medicine, Thurston Arthritis Research Center
Abstract
  • Abstract Background Associations of socioeconomic status (SES) with the prevalence of various forms of arthritis are well documented. Increasing evidence suggests that SES during childhood is a lasting determinant of health, but its association with the onset of arthritis remains unclear. Methods Cross-sectional data on 1276 participants originated from 22 family practices in North-Carolina, USA. We created 4-level (high, medium, low, lowest) current SES and childhood SES summary scores based on parental and participant education, occupation and homeownership. We investigated associations of individual SES characteristics, summary scores and SES trajectories (e.g. high/low) with self-reported arthritis in logistic regression models progressively adjusted for race and gender, age, then BMI, and clustered by family practice. Results We found evidence for independent associations of both childhood and current SES with the reporting of arthritis across our models. In covariate-adjusted models simultaneously including current and childhood SES, compared with high SES participants in the lowest childhood SES category (OR = 1.39 [95% CI = 1.04, 1.85]) and those in the low (OR = 1.66 [95% CI = 1.14, 2.42]) and lowest (OR = 2.08 [95% CI = 1.16, 3.74]) categories of current SES had significantly greater odds of having self-reported arthritis. Conclusions Current SES and childhood SES are both associated with the odds of reporting arthritis within this primary-care population, although the possibly superseding influence of existing circumstances must be noted. BMI was a likely mechanism in the association of childhood SES with arthritis onset, and research is needed to elucidate further pathways linking the socioeconomic environment across life-stages and the development of rheumatic diseases.
Date of publication
Identifier
  • 24256740
  • doi:10.1186/1471-2474-14-327
Resource type
  • Article
Rights statement
  • In Copyright
Rights holder
  • Antoine R Baldassari et al.; licensee BioMed Central Ltd.
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Journal title
  • BMC Musculoskeletal Disorders
Journal volume
  • 14
Journal issue
  • 1
Page start
  • 327
Language
  • English
Is the article or chapter peer-reviewed?
  • Yes
ISSN
  • 1471-2474
Bibliographic citation
  • BMC Musculoskeletal Disorders. 2013 Nov 20;14(1):327
Access
  • Open Access
Publisher
  • BioMed Central Ltd
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