The relationship between grip strength, reaction time, and cerebral white matter integrity in the anterior internal capsule of healthy older adults

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  • March 22, 2019
Creator
  • Gravitt, Karla
    • Affiliation: College of Arts and Sciences, Department of Exercise and Sport Science
Abstract
  • This study investigated the relationship between grip strength, reaction time, and cerebral white matter integrity (CWMI) in the anterior internal capsule (AIC) of healthy older adults. Gender and hemispheric influences were also explored. Fifteen subjects (8 males, 7 females; 66.2 ± 5.8 years old) completed dynamic grip strength and reaction time testing (recognition and combined) on the dominant hand. Magnetic resonance imaging with diffusion tensor imaging determined CWMI in the AIC via computation of fractional anisotropy (FA) values. A simple regression revealed a positive correlation between grip strength and FA values in the left AIC (r = 0.577; r2 = 0.33, p = 0.039). A positive correlation between combined reaction time and FA values was found in the right AIC (r = 0.688; r2 = 0.47, p = 0.037). No significant gender relationships were noted. The potential hemispheric influence of fitness on CWMI should be further explored.
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  • In Copyright
Advisor
  • Marks, Bonita L.
Degree granting institution
  • University of North Carolina at Chapel Hill
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  • Open access
Date uploaded
  • October 11, 2010

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