The effect of exercise in the heat on circulating tumor necrosis factor-α concentration Public Deposited
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- Last Modified
- March 21, 2019
Berry, Mark P.
- Affiliation: College of Arts and Sciences, Department of Exercise and Sport Science
- To examine the effect of a hot environment on the TNF-α response to exercise, eight male subjects (24 ± 1.7 years of age, 1.80 ± 0.06 m, 78.3 ± 6.06 kg, 24.2 ± 1.9 mg/m2, 53.8 ± 3.7 ml/kg/min; mean ± SD) completed two, 40 min underwater cycling sessions at an intensity of 65% VO2peak. One session took place while submerged in cool water (25.5 ± 0.02°C) and the other in hot water (38.1 ± 0.06°C). TNF-α concentration was determined by an enzyme-linked immunosorbent assay from blood samples obtained immediately prior to, immediately post and two-hours after each exercise session. The pre-exercise TNF-α concentration for the cool and hot trials was 1.76 ± 0.94 and 1.58 ± 1.09, while the postexercise concentration was 1.62 ± .81 and 1.54 ± 1.03, and the two hour post-exercise was 1.75 ± 0.80 and 1.63 ± 1.03, respectively. No significant differences were found between the pre, post-exercise or two hour post-exercise TNF-α concentration within or between the exercise bouts (p > 0.05). No statistically significant relationship was found between change in core temperature and change in TNF-α concentration (r = .366; p > 0.05). The results of the present study suggest that forty minutes of moderate-intensity exercise in a cool or hot environment does not elevate TNF-α concentration immediately post or two hours postexercise.
- Date of publication
- August 2008
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- In Copyright
- McMurray, Robert G.
- Degree granting institution
- University of North Carolina at Chapel Hill
- Open access
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|The effect of exercise in the heat on circulating tumor necrosis factor-[alpha] concentration||2019-04-07||Public||