The effect of using a powered toothbrush on MCP-1 and RANTES levels in patients with gingivitis

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  • March 22, 2019
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  • Paquette, Linda Lee
    • Adams School of Dentistry, Division of Allied Dental Education, Dental Hygiene Master's Program
Abstract
  • This pilot study investigated if a powered toothbrush significantly reduced the concentration of MCP-1 and RANTES over time in a gingivitis population, when compared to a manual toothbrush. Twenty gingivitis patients, 18-65 years of age with pocket depths [less than or equal to] 6mm and a minimum of 10% bleeding upon probing were enrolled. Participants were seen for 5 study visits and gingival crevicular fluid samples were collected at baseline and 24 weeks. With the exception of race (p=0.01), no statistically significant differences were found between the groups at baseline in clinical measurements, GCF levels of MCP-1 and RANTES and demographics. When comparing the treatment group to the control, no statistical differences were found between the GCF levels for MCP-1 and RANTES at baseline and 24 weeks post treatment (p=0.20 and p=0.19, respectively). Additional large sample studies are needed to determine if these findings can be confirmed.
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  • In Copyright
Advisor
  • Jared, Heather Lee
Degree granting institution
  • University of North Carolina at Chapel Hill
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  • Open access
Date uploaded
  • October 19, 2010

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file details The effect of using a powered toothbrush on MCP-1 and RANTES levels in patients with gingivitis October 19, 2010 Public Download