NEURAL CIRCUIT DYNAMICS AND FUNCTION OF COMPLEX BEHAVIORAL STATES Public Deposited

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Last Modified
  • March 19, 2019
Creator
  • Jennings, Joshua
    • Affiliation: School of Medicine, UNC Neuroscience Center, Neuroscience Curriculum
Abstract
  • Mammalian neural circuits are sophisticated biological systems that choreograph behavioral processes vital for survival. While the inherent complexity of discrete neural circuits has proven difficult to decipher, many parallel methodological developments promise to help delineate the function and connectivity of molecularly defined neural circuits. Here, I utilize novel neurotechniques to precisely monitor and manipulate anxiety- and feeding-related circuit activity. By using a holistic, multifaceted approach for perturbing and measuring neural circuit dynamics, we begin to provide a framework for understanding how adaptive and maladaptive behavioral states are manifested through the cooperative interactions of discrete extended amygdala, midbrain, and hypothalamic circuit elements.
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  • In Copyright
Advisor
  • Stuber, Garret
  • Besheer, Joyce
  • Bulik, Cynthia
  • Smith, Spencer
  • Philpot, Benjamin
Degree
  • Doctor of Philosophy
Degree granting institution
  • University of North Carolina at Chapel Hill Graduate School
Graduation year
  • 2014
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  • Chapel Hill, NC
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