Pragmatic language in autism and fragile X syndrome: links with physiological arousal and anxiety Public Deposited
- Last Modified
- March 22, 2019
- Creator
-
Klusek, Jessica
- Affiliation: School of Medicine, Department of Allied Health Sciences, Division of Speech and Hearing Sciences
- Abstract
- This dissertation is comprised of three manuscripts focused on delineating pragmatic language profiles in children with autism and fragile X syndrome, and on understanding the potential impact of physiological dysregulation on these profiles. The first manuscript presents a review of the existing literature on physiological arousal in autism and fragile X syndrome, with a focus on the relationship between arousal modulation and social competence. The second two manuscripts present original research: the first consists of a cross-population comparison of pragmatic language in autism and fragile X syndrome; the second extends upon this line of research by examining cardiac arousal as a mechanism that may play a role of social-communicative impairment in these disorders. These three manuscripts address the extent to which pragmatic language deficits overlap in autism and fragile X syndrome, and whether such deficits are linked with dysfunction of the autonomic nervous system. This work has implications for developing syndrome-specific interventions and ultimately may inform biological pathways that may be common to autism and fragile X syndrome.
- Date of publication
- May 2012
- DOI
- Resource type
- Rights statement
- In Copyright
- Advisor
- Losh, Molly
- Degree
- Doctor of Philosophy
- Graduation year
- 2012
- Language
- Publisher
- Parents:
This work has no parents.
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