The effect of glycogen depletion on responses of interleukin-1β, interleukin-6, and interleukin-10 to maximal exercise Public Deposited

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Last Modified
  • March 22, 2019
Creator
  • Leppert, Kyle McDonald
    • Affiliation: College of Arts and Sciences, Department of Exercise and Sport Science
Abstract
  • The purpose of this study was to investigate the influence of glycogen stores on the maximal responses of IL-1β, IL-6, and IL-10 to a discontinuous, progressive cycle ergometry test. Eight trained cyclists completed two progressive maximal cycle ergometry tests (5 min stages with 5 min recovery), one normally fed and one following glycogen-depletion (2-h at 60-65% VO2max). Percent changes in circulating IL-1β, IL-6, and IL-10 were measured during exercise and recovery and peak changes were compared. IL-6 showed a trend towards significant interaction effect of exercise time and trial condition (p = 0.054) in both trials, but there were no significant differences among percent changes in IL-1β or IL-10. Glycogenreduction appeared to cause all cytokines to peak earlier, but the trend was not significant.
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  • In Copyright
Advisor
  • McMurray, Robert G.
Degree granting institution
  • University of North Carolina at Chapel Hill
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  • Open access
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