Influence of Probiotics on Body Composition and Health in Occupational Shift-workers Public Deposited

Downloadable Content

Download PDF
Last Modified
  • March 20, 2019
  • Mock, Meredith
    • Affiliation: College of Arts and Sciences, Department of Exercise and Sport Science
  • The present study sought to investigate the effects of a multi-strain probiotic (PRO) on body composition, regional adiposity, and a series of associated metabolic health outcomes. Female healthcare workers employed on a rotating-shift schedule (n=41) completed baseline anthropometric assessments, a fasted blood draw, mood questionnaires, and an exercise fatigue test. Identical post-tests occurred following six weeks daily supplementation with (PRO) or placebo (PLA). PRO attenuated fat mass gains (Δ0.14; CI: -0.46–0.75kg) compared to PLA (Δ0.79 kg; CI: 0.03–1.54 kg), and resulted in modest reductions in visceral adiposity (VAT). Metabolic biomarkers (total cholesterol, HDL, and glucose) were not influenced by either treatment (p>0.05). Non-significant, yet clinically relevant improvements in anxiety and fatigue were observed with PRO, but exercise performance was unaffected. Results indicate a potential protective effect of PRO, and may direct future occupational health investigations of various probiotic strains in susceptible populations.
Date of publication
Resource type
Rights statement
  • In Copyright
  • Trexler, Eric
  • Beck, Melinda A.
  • Smith-Ryan, Abbie
  • Kucera, Kristen
  • Master of Arts
Degree granting institution
  • University of North Carolina at Chapel Hill Graduate School
Graduation year
  • 2017

This work has no parents.