An In Vitro Study of Antimicrobial Properties of an Orthodontic Sealant/Adhesive Containing Selenium

An In Vitro Study of Antimicrobial Properties of an Orthodontic Sealant/Adhesive Containing Selenium Public Deposited

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Abstract

Introduction: White spot lesions are a significant risk to patients undergoing orthodontic therapy. Antimicrobial agents are thought to reduce the incidence of white spot lesions due to their ability to kill cariogenic bacteria. The objective of this study was to characterize and quantify the antimicrobial properties of an orthodontic bonding system containing selenium (SeLECT Defense) compared to traditional orthodontic materials. Methods: SeLECT Defense sealant, adhesive, and band cement were compared to eight other materials. An Agar Diffusion Assay was used to demonstrate the inhibition of growth of S. mutans and L. acidophilus. A Direct Contact Inhibition Assay was used to quantify the bactericidal nature of the materials. Results: Several materials, including SeLECT Defense products, demonstrated antimicrobial properties in the Agar Diffusion Assay. Several materials, but not SeLECT Defense products, demonstrated bactericidal properties in the Direct Contact Inhibition Assay. Conclusions: Orthodontic bonding materials, including those containing Selenium, possess antimicrobial properties.

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