Patient-specific anatomical illustration via model-guided texture synthesis Public Deposited

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  • March 21, 2019
  • Kaynar Kabul, Ilknur
    • Affiliation: College of Arts and Sciences, Department of Computer Science
  • Medical illustrations can make powerful use of textures to attractively, effectively, and efficiently visualize the appearance of the surface or cut surface of anatomic structures. It can do this by implying the anatomic structure's physical composition and clarifying its identity and 3-D shape. Current visualization methods are only capable of conveying detailed information about the orientation, internal structure, and other local properties of the anatomical objects for a typical individual, not for a particular patient. Although one can derive the shape of the individual patient's object from CT or MRI, it is important to apply these illustrative techniques to those particular shapes. In this research patient-specific anatomical illustrations are created by model-guided texture synthesis (MGTS). Given 2D exemplar textures and model-based guidance information as input, MGTS uses exemplar-based texture synthesis techniques to create patient-specific surface and solid textures. It consists of three main components. The first component includes a novel texture metamorphosis approach for creating interpolated exemplar textures given two exemplar textures. This component uses an energy optimization scheme derived from optimal control principles that utilizes intensity and structure information in obtaining the transformation. The second component consists of creating the model-based guidance information, such as directions and layers, for that specific model. This component uses coordinates implied by discrete medial 3D anatomical models (m-reps). The last component accomplishes exemplar-based texture synthesis by textures whose characteristics are spatially variant on and inside the 3D models. It considers the exemplar textures from the first component and guidance information from the second component in synthesizing high-quality, high-resolution solid and surface textures. Patient-specific illustrations with a variety of textures for different anatomical models, such as muscles and bones, are shown to be useful for our clinician to comprehend the shape of the models under radiation dose and to distinguish the models from one another.
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  • ... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Computer Science.
  • Pizer, Stephen M.

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