The Use of Dexamethasone vs Prednisone in the Treatment of Asthma Exacerbation

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  • February 26, 2019
Creator
  • Higgins, Leana
    • Affiliation: School of Medicine, Department of Allied Health Sciences, Physician Assistant Program
Abstract
  • Asthma accounts for 2.1 million unscheduled ED visits annually, with a prevalence of 8.4% of the US population. Systemic corticosteroids serve as a cornerstone of acute asthma therapy, decreasing relapse rate, length of stay, and hospitalization rates. Since prednisone has multiple side effects and problematic compliance, studies have been conducted to determine if dexamethasone is as effective in the treatment of asthma exacerbation. This review evaluated a Cochrane systematic review, as well as three additional studies not included in that review. The conclusion was that dexamethasone is a promising alternative to prednisone in treating asthma exacerbation in both adults and children. However, in order for this possibility to be readily adopted into guidelines and clinical practice, higher quality and more consistent data needs to be obtained.
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  • In Copyright
Reviewer
  • Faurot, Kim
  • Tintinalli, Judith
Degree
  • Master of Health Science
Degree granting institution
  • University of North Carolina at Chapel Hill
Graduation year
  • 2017
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  • 03017bbf-d2c5-4c32-b5ff-fb580cd5f16e

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