The Use of Dexamethasone vs Prednisone in the Treatment of Asthma Exacerbation
Public Deposited- Last Modified
- February 26, 2019
- Creator
-
Higgins, Leana
- Affiliation: School of Medicine, Department of Allied Health Sciences, Physician Assistant Program
- Abstract
- Asthma accounts for 2.1 million unscheduled ED visits annually, with a prevalence of 8.4% of the US population. Systemic corticosteroids serve as a cornerstone of acute asthma therapy, decreasing relapse rate, length of stay, and hospitalization rates. Since prednisone has multiple side effects and problematic compliance, studies have been conducted to determine if dexamethasone is as effective in the treatment of asthma exacerbation. This review evaluated a Cochrane systematic review, as well as three additional studies not included in that review. The conclusion was that dexamethasone is a promising alternative to prednisone in treating asthma exacerbation in both adults and children. However, in order for this possibility to be readily adopted into guidelines and clinical practice, higher quality and more consistent data needs to be obtained.
- Date of publication
- 2017
- Keyword
- DOI
- Resource type
- Rights statement
- In Copyright
- Reviewer
- Faurot, Kim
- Tintinalli, Judith
- Degree
- Master of Health Science
- Degree granting institution
- University of North Carolina at Chapel Hill
- Graduation year
- 2017
- Language
- Deposit record
- 03017bbf-d2c5-4c32-b5ff-fb580cd5f16e
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