Association of opioid dose reduction with opioid overdose and opioid use disorder among patients on high-dose long-term opioid therapy in North Carolina

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  • September 27, 2022
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  • Diprete, Bethany L.
    • Affiliation: Gillings School of Global Public Health
  • Ranapurwala, Shabbar I
    • Affiliation: Gillings School of Global Public Health, Department of Epidemiology
  • Maierhofer, Courtney N
    • Affiliation: Gillings School of Global Public Health
  • Fulcher, Naoko
    • Affiliation: Injury Prevention Research Center
  • Chekminski, Paul R
    • Affiliation: School of Medicine
  • Ives, Timothy J
    • Affiliation: School of Medicine
  • Dasgupta, Nabarun
    • Affiliation: Injury Prevention Research Center
  • Go, Vivian F
    • Affiliation: Gillings School of Global Public Health, Department of Health Behavior
  • Pence, Brian W
    • Affiliation: Gillings School of Global Public Health, Department of Epidemiology
Abstract
  • Presentation at the 38th International Conference on Pharmacoepidemiology [ICPE]. Objective: to characterize the association between rapid reduction or abrupt discontinuation of opioid therapy* and incidence of opioid overdose and OUD among patients receiving high-dose long-term opioid therapy (HDLTOT). [* vs maintained or gradual reduction]
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  • 38th International Conference on Pharmacoepidemiology [ICPE]
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