The association of spatial T wave axis deviation with incident coronary events. The ARIC cohort
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Vaidean, Georgeta D, et al. The Association of Spatial T Wave Axis Deviation with Incident Coronary Events. The Aric Cohort. BioMed Central Ltd, 2005. https://doi.org/10.17615/j61p-k196APA
Vaidean, G., Rautaharju, P., Prineas, R., Whitsel, E., Chambless, L., Folsom, A., Rosamond, W., Zhang, Z., Crow, R., & Heiss, G. (2005). The association of spatial T wave axis deviation with incident coronary events. The ARIC cohort. BioMed Central Ltd. https://doi.org/10.17615/j61p-k196Chicago
Vaidean, Georgeta D, Pentti M Rautaharju, Ronald J Prineas, Eric Whitsel, Lloyd E Chambless, Aaron R Folsom, Wayne D Rosamond et al. 2005. The Association of Spatial T Wave Axis Deviation with Incident Coronary Events. The Aric Cohort. BioMed Central Ltd. https://doi.org/10.17615/j61p-k196- Creator
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Vaidean, Georgeta D
- Affiliation: Gillings School of Global Public Health, Department of Epidemiology
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Rautaharju, Pentti M
- Other Affiliation: Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
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Prineas, Ronald J
- Other Affiliation: Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
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Whitsel, Eric
- Affiliation: Gillings School of Global Public Health, Department of Epidemiology
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Chambless, Lloyd E
- Affiliation: Gillings School of Global Public Health, Department of Biostatistics
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Folsom, Aaron R
- Other Affiliation: Division of Epidemiology, University of Minnesota, Minneapolis, Minnesota, USA
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Rosamond, Wayne D.
- Affiliation: Gillings School of Global Public Health, Department of Epidemiology
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Zhang, Zhu-Ming
- Other Affiliation: Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
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Crow, Richard S
- Other Affiliation: Division of Epidemiology, University of Minnesota, Minneapolis, Minnesota, USA
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Heiss, Gerardo
- Affiliation: Gillings School of Global Public Health, Department of Epidemiology
- Abstract
- Abstract Background Although current evidence suggests that the spatial T wave axis captures important information about ventricular repolarization abnormalities, there are only a few and discordant epidemiologic studies addressing the ability of the spatial T wave axis to predict coronary heart disease (CHD) occurrence. Methods This prospective study analyzed data from 12,256 middle-aged African American and white men and women, from the Atherosclerosis Risk in Communities Study (ARIC). Following a standardized protocol, resting standard 12-lead, 10-second electrocardiograms were digitized and analyzed with the Marquette GE program. The median follow-up time was 12.1 years; incident coronary heart disease comprised fatal and non-fatal CHD events. Results The incidence rate of CHD was 4.26, 4.18, 4.28 and 5.62 per 1000 person-years respectively, across the spatial T wave axis quartiles. Among women for every 10 degrees increase in the spatial T wave axis deviation, there was an estimated increase in the risk of CHD of 1.16 (95% CI 1.04–1.28). After adjustment for age, height, weight, smoking, hypertension, diabetes, QRS axis and minor T wave abnormalities, this hazard rate ratio for women fell to 1.03 (0.92–1.14). The corresponding crude and adjusted hazard ratios for men were 1.05 (95% CI 0.96–1.15) and 0.95 (0.86–1.04) respectively. Conclusions In conclusion, this prospective, population-based, bi-ethnic study of men and women free of coronary heart disease at baseline shows that spatial T wave axis deviation is not associated with incident coronary events during long-term follow up. It is doubtful that spatial T wave axis deviation would add benefit in the prediction of CHD events above and beyond the current traditional risk factors.
- Date of publication
- January 11, 2005
- DOI
- Identifier
- Resource type
- Article
- Rights statement
- In Copyright
- Rights holder
- Georgeta D Vaidean et al.; licensee BioMed Central Ltd.
- License
- Journal title
- BMC Cardiovascular Disorders
- Journal volume
- 5
- Journal issue
- 1
- Page start
- 2
- Language
- English
- Is the article or chapter peer-reviewed?
- Yes
- ISSN
- 1471-2261
- Bibliographic citation
- BMC Cardiovascular Disorders. 2005 Jan 11;5(1):2
- Publisher
- BioMed Central Ltd
- Access right
- Open Access
- Date uploaded
- September 5, 2012
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