ingest cdrApp 2018-06-13T21:05:20.389Z 51cd2fe2-3fd7-401f-a923-a97bc3db68a2 modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-06-13T22:34:42.823Z Setting exclusive relation addDatastream MD_TECHNICAL fedoraAdmin 2018-06-13T22:34:54.050Z Adding technical metadata derived by FITS addDatastream MD_FULL_TEXT fedoraAdmin 2018-06-13T22:35:16.994Z Adding full text metadata extracted by Apache Tika modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-06-13T22:35:39.339Z Setting exclusive relation modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-07-11T00:09:57.649Z Setting invalid vocabulary terms modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-07-11T00:10:10.334Z modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-07-16T17:15:35.107Z Setting invalid vocabulary terms modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-07-17T20:10:26.603Z Setting invalid vocabulary terms modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-07-17T20:10:37.955Z modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-08-08T19:37:16.942Z Setting invalid vocabulary terms modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-08-08T19:37:28.271Z modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-08-15T16:46:03.454Z Setting invalid vocabulary terms modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-08-15T16:46:14.794Z modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-08-16T19:48:58.329Z Setting invalid vocabulary terms modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-08-16T19:49:09.445Z modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-09-21T17:14:29.762Z Setting invalid vocabulary terms modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-09-21T17:14:41.223Z modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-09-26T20:20:22.420Z Setting invalid vocabulary terms modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-09-26T20:20:33.768Z modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-10-11T21:03:04.525Z Setting invalid vocabulary terms modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-10-11T21:03:15.885Z modifyDatastreamByValue RELS-EXT fedoraAdmin 2019-03-20T14:19:26.703Z Setting invalid vocabulary terms modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2019-03-20T14:19:40.082Z Adam Sage Author Pharmaceutical Sciences Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. Spring 2018 2018 Pharmaceutical sciences Blood Pressure, Data Visualization, Health Education, Health Literacy, Hypertension, Mobile Health eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Pharmaceutical Sciences Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text Adam Sage Author Pharmaceutical Sciences Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. Spring 2018 2018 Pharmaceutical sciences Blood Pressure, Data Visualization, Health Education, Health Literacy, Hypertension, Mobile Health eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Pharmaceutical Sciences Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text Adam Sage Author Pharmaceutical Sciences Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. Spring 2018 2018 Pharmaceutical sciences Blood Pressure, Data Visualization, Health Education, Health Literacy, Hypertension, Mobile Health eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Pharmaceutical Sciences Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text Adam Sage Author Pharmaceutical Sciences Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. Spring 2018 2018 Pharmaceutical sciences Blood Pressure, Data Visualization, Health Education, Health Literacy, Hypertension, Mobile Health eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Pharmaceutical Sciences Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text Adam Sage Author Pharmaceutical Sciences Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. Spring 2018 2018 Pharmaceutical sciences Blood Pressure, Data Visualization, Health Education, Health Literacy, Hypertension, Mobile Health eng Doctor of Philosophy Dissertation Pharmaceutical Sciences Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text University of North Carolina at Chapel Hill Degree granting institution Adam Sage Author Pharmaceutical Sciences Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. Spring 2018 2018 Pharmaceutical sciences Blood Pressure, Data Visualization, Health Education, Health Literacy, Hypertension, Mobile Health eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Pharmaceutical Sciences Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text Adam Sage Author Pharmaceutical Sciences Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. Spring 2018 2018 Pharmaceutical sciences Blood Pressure, Data Visualization, Health Education, Health Literacy, Hypertension, Mobile Health eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Pharmaceutical Sciences Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text Adam Sage Creator Pharmaceutical Sciences Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. Pharmaceutical sciences Blood Pressure; Data Visualization; Health Education; Health Literacy; Hypertension; Mobile Health eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Pharmaceutical Sciences Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text 2018 2018-05 Adam Sage Author Pharmaceutical Sciences Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. Spring 2018 2018 Pharmaceutical sciences Blood Pressure, Data Visualization, Health Education, Health Literacy, Hypertension, Mobile Health eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Pharmaceutical Sciences Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text Adam Sage Creator Pharmaceutical Sciences Program Optimizing Patient Comprehension of Information Visualizations for Medication Adherence and Blood Pressure Introduction: This dissertation focused on designing hypertension self-management visualizations that facilitate patient comprehension of blood pressure and medication adherence information. The objectives of this research were to: 1) assess patient preferences and understanding of visualization features; 2) assess whether condensing the display of blood pressure and medication adherence information into a single visualization improves patient comprehension of the inferred relationship between medication adherence and blood pressure control (compared to separate visualizations); 3) assess whether health literacy moderates the effect of condensed visualizations on comprehension; and 4) assess the validity and reliability of a newly developed hypertension-related visualization comprehension scale. Methods: Patients with hypertension (n=6) participated in user assessments to understand preferences for visualization features. Another sample of patients with hypertension (n=6) participated in cognitive interviews that assessed understanding of visualizations that incorporated patient preferences. A survey experiment with patients with hypertension (n=137) then assessed whether condensed visualizations improved comprehension of blood pressure and medication adherence information. Multiple regression analysis was used to assess the main effect of visualization type (condensed versus separate display) on comprehension, and the moderating effect of health literacy on comprehension. Exploratory and confirmatory factor analysis were used to assess the validity and reliability of the comprehension scale. Results: Patients preferred visualizations with blue/orange color-coded culturally recognizable symbols to show medication adherence, and the use of labeled blood pressure data points, horizontal reference lines, and a shaded “normal” blood pressure zone. Patients best understood a shaded “normal” blood pressure zone with color-coded symbols to show medication adherence. Condensed visualizations did not significantly improve comprehension, and health literacy did not moderate the relationship between visualization type and comprehension. However, greater health literacy (B=0.61, p=.0001) and hypertension knowledge (B=0.10, p<0.0001) were positively associated with comprehension. Exploratory and confirmatory factor analyses supported a unidimensional 4-item solution for the comprehension scale. Conclusion: This study is an important step in developing useful and useable data visualizations for self-managing HTN. Condensed-display visualizations did not improve patient comprehension of BP and medication adherence information. Future research should further investigate how to design visualizations that improve comprehension, specifically for patients with low health literacy. 2018-05 2018 Pharmaceutical sciences Blood Pressure; Data Visualization; Health Education; Health Literacy; Hypertension; Mobile Health eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Delesha Carpenter Thesis advisor Susan Blalock Thesis advisor Stacy Bailey Thesis advisor Arlene Chung Thesis advisor David Gotz Thesis advisor text Sage_unc_0153D_17762.pdf uuid:5c6a938a-0e77-469f-b94c-6581f1424ad1 proquest 2020-06-13T00:00:00 2018-04-11T23:30:16Z application/pdf 12705251 affiliation|Pharmaceutical Sciences Program