ingest cdrApp 2018-08-23T18:35:56.236Z d39a25df-af15-48e9-aec2-c9af81a997a2 modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-08-23T18:36:46.514Z Setting exclusive relation addDatastream MD_TECHNICAL fedoraAdmin 2018-08-23T18:36:57.621Z Adding technical metadata derived by FITS addDatastream MD_FULL_TEXT fedoraAdmin 2018-08-23T18:37:19.992Z Adding full text metadata extracted by Apache Tika modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-08-23T18:37:42.182Z Setting exclusive relation modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-09-27T02:50:59.762Z modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2019-03-20T21:53:01.657Z Victoria Hawley Author Department of Exercise and Sport Science College of Arts and Sciences THE INFLUENCE OF A FATIGUE-INDUCING ACUTE BOUT OF EXERCISE ON LANDING BIOMECHANICS AND MARKERS OF MUSCLE STRESS PURPOSE: To determine the effect of an acute bout of high-intensity exercise on 3D landing biomechanics (sagittal plane knee angle, frontal plane knee angle, sagittal plane hip angle, frontal plane hip angle, vGRF) and creatine kinase release 30 minutes and 24 hours after an acute bout of high-intensity exercise. A secondary purpose was to determine the relationship between landing biomechanics and creatine kinase release at baseline, 30 minutes and 24 hours after an acute bout of high-intensity exercise. METHODS: Twenty subjects completed a speed-only VO2submax test to determine the ventilatory threshold (VT). Subjects then completed 5 bouts of running at VT for 5 minutes, 10 jump landings, and 10 split squats, followed by 2 rounds of 10 jump landings and 20 split squats. A blood draw and 3D biomechanical analysis were completed pre-fatigue, 30 minutes post-fatigue, and 24 hours post-fatigue. One-way within-subjects ANOVAs were used to determine the effect of an acute bout of fatiguing exercise on landing biomechanics and creatine kinase release pre-fatigue, 30 minutes post-fatigue, and 24 hours post-fatigue. A multiple regression was employed to determine the relationship between creatine kinase release and landing biomechanics pre-fatigue, 30 minutes post-fatigue, and 24 hours post-fatigue. RESULTS: Knee sagittal Euler angle and knee frontal world angle at initial contact significantly decreased from Pre- to Post-30 (p=0.000 and p=0.008, respectively). Knee frontal world angle at initial contact significantly decreased from pre- to post-24 (p=0.015). CK significantly increased from Pre- to Post-30 (p=0.000), Pre- to Post-24 (p=0.000), and Post-30 to Post-24 (p=0.033). There were significant relationships between baseline vGRF and %change in CK from Pre- to Post-24 (r= -0.518, p= 0.028), baseline vGRF and baseline maximal knee sagittal angle (r= -0.518, p=0.019), and baseline vGRF and baseline minimal hip sagittal angle (r= 0.555, p=0.011). CONCLUSION: An acute bout of fatigue-inducing exercise increases knee valgus and decreases knee flexion at initial contact and increases CK immediately after and 24 hours after exercise, with peak values occurring at 24 hours after exercise. Increased vGRF is associated with less hip and knee flexion, and subsequently less CK release. Spring 2018 2018 Kinesiology Health sciences ACL Injury, Biomechanics, Creatine Kinase, Fatigue, Landing Mechanics, Muscle Stress eng Master of Arts Thesis University of North Carolina at Chapel Hill Graduate School Degree granting institution Exercise and Sport Science Claudio Battaglini Thesis advisor Darin Padua Thesis advisor Barnett Frank Thesis advisor text Victoria Hawley Creator Department of Exercise and Sport Science College of Arts and Sciences THE INFLUENCE OF A FATIGUE-INDUCING ACUTE BOUT OF EXERCISE ON LANDING BIOMECHANICS AND MARKERS OF MUSCLE STRESS PURPOSE: To determine the effect of an acute bout of high-intensity exercise on 3D landing biomechanics (sagittal plane knee angle, frontal plane knee angle, sagittal plane hip angle, frontal plane hip angle, vGRF) and creatine kinase release 30 minutes and 24 hours after an acute bout of high-intensity exercise. A secondary purpose was to determine the relationship between landing biomechanics and creatine kinase release at baseline, 30 minutes and 24 hours after an acute bout of high-intensity exercise. METHODS: Twenty subjects completed a speed-only VO2submax test to determine the ventilatory threshold (VT). Subjects then completed 5 bouts of running at VT for 5 minutes, 10 jump landings, and 10 split squats, followed by 2 rounds of 10 jump landings and 20 split squats. A blood draw and 3D biomechanical analysis were completed pre-fatigue, 30 minutes post-fatigue, and 24 hours post-fatigue. One-way within-subjects ANOVAs were used to determine the effect of an acute bout of fatiguing exercise on landing biomechanics and creatine kinase release pre-fatigue, 30 minutes post-fatigue, and 24 hours post-fatigue. A multiple regression was employed to determine the relationship between creatine kinase release and landing biomechanics pre-fatigue, 30 minutes post-fatigue, and 24 hours post-fatigue. RESULTS: Knee sagittal Euler angle and knee frontal world angle at initial contact significantly decreased from Pre- to Post-30 (p=0.000 and p=0.008, respectively). Knee frontal world angle at initial contact significantly decreased from pre- to post-24 (p=0.015). CK significantly increased from Pre- to Post-30 (p=0.000), Pre- to Post-24 (p=0.000), and Post-30 to Post-24 (p=0.033). There were significant relationships between baseline vGRF and %change in CK from Pre- to Post-24 (r= -0.518, p= 0.028), baseline vGRF and baseline maximal knee sagittal angle (r= -0.518, p=0.019), and baseline vGRF and baseline minimal hip sagittal angle (r= 0.555, p=0.011). CONCLUSION: An acute bout of fatigue-inducing exercise increases knee valgus and decreases knee flexion at initial contact and increases CK immediately after and 24 hours after exercise, with peak values occurring at 24 hours after exercise. Increased vGRF is associated with less hip and knee flexion, and subsequently less CK release. Kinesiology Health sciences ACL Injury; Biomechanics; Creatine Kinase; Fatigue; Landing Mechanics; Muscle Stress Master of Arts Masters Thesis University of North Carolina at Chapel Hill Graduate School Degree granting institution Exercise and Sport Science Claudio Battaglini Thesis advisor Darin Padua Thesis advisor Barnett Frank Thesis advisor 2018 2018-05 eng text Victoria Hawley Creator Department of Exercise and Sport Science College of Arts and Sciences THE INFLUENCE OF A FATIGUE-INDUCING ACUTE BOUT OF EXERCISE ON LANDING BIOMECHANICS AND MARKERS OF MUSCLE STRESS PURPOSE: To determine the effect of an acute bout of high-intensity exercise on 3D landing biomechanics (sagittal plane knee angle, frontal plane knee angle, sagittal plane hip angle, frontal plane hip angle, vGRF) and creatine kinase release 30 minutes and 24 hours after an acute bout of high-intensity exercise. A secondary purpose was to determine the relationship between landing biomechanics and creatine kinase release at baseline, 30 minutes and 24 hours after an acute bout of high-intensity exercise. METHODS: Twenty subjects completed a speed-only VO2submax test to determine the ventilatory threshold (VT). Subjects then completed 5 bouts of running at VT for 5 minutes, 10 jump landings, and 10 split squats, followed by 2 rounds of 10 jump landings and 20 split squats. A blood draw and 3D biomechanical analysis were completed pre-fatigue, 30 minutes post-fatigue, and 24 hours post-fatigue. One-way within-subjects ANOVAs were used to determine the effect of an acute bout of fatiguing exercise on landing biomechanics and creatine kinase release pre-fatigue, 30 minutes post-fatigue, and 24 hours post-fatigue. A multiple regression was employed to determine the relationship between creatine kinase release and landing biomechanics pre-fatigue, 30 minutes post-fatigue, and 24 hours post-fatigue. RESULTS: Knee sagittal Euler angle and knee frontal world angle at initial contact significantly decreased from Pre- to Post-30 (p=0.000 and p=0.008, respectively). Knee frontal world angle at initial contact significantly decreased from pre- to post-24 (p=0.015). CK significantly increased from Pre- to Post-30 (p=0.000), Pre- to Post-24 (p=0.000), and Post-30 to Post-24 (p=0.033). There were significant relationships between baseline vGRF and %change in CK from Pre- to Post-24 (r= -0.518, p= 0.028), baseline vGRF and baseline maximal knee sagittal angle (r= -0.518, p=0.019), and baseline vGRF and baseline minimal hip sagittal angle (r= 0.555, p=0.011). CONCLUSION: An acute bout of fatigue-inducing exercise increases knee valgus and decreases knee flexion at initial contact and increases CK immediately after and 24 hours after exercise, with peak values occurring at 24 hours after exercise. Increased vGRF is associated with less hip and knee flexion, and subsequently less CK release. Kinesiology Health sciences ACL Injury; Biomechanics; Creatine Kinase; Fatigue; Landing Mechanics; Muscle Stress Master of Arts Masters Thesis University of North Carolina at Chapel Hill Graduate School Degree granting institution Claudio Battaglini Thesis advisor Darin Padua Thesis advisor Barnett Frank Thesis advisor 2018 2018-05 eng text Hawley_unc_0153M_17976.pdf uuid:4140275a-f099-41b4-83b1-695cc1370513 2020-08-23T00:00:00 2018-06-29T19:24:48Z proquest application/pdf 3340073