Figure 1A
>He-ELAV
TNLIVNYLPQGMELETMRKLFENIGPVESCKLIKDRQTQSLGFGFVNYIS
EESAVVALRQLNGIRIQNKNIKVSYARKSSESIKGANLYVSGFPKSWVVN
DLEAYFQPYGEVITARILIDGVGFVRFDQKGQADRAIEKLHGRIPPGQTE
PIQVKFANNPSVLFVYNLPSETEDATLWQLFGQFGPGNVKIVKDATTQKN
KGYAFITMTSYDGALCAITALNGYQLGNRVLQVSFKTGG
>An-ELAV
TNLIINYLPQTMTQDEIKDLFGSVGAIESCKLVRDKTTQSLGYGFVNFIR
TEDAEKAVKTMNGLRLQNKTIKVSFARPSSESIKFSNLYVSNLPRSMTQQ
ELESLFADFGSIISSKILCNSVGFIRFDQRAEAEIAINKLNGSIPKGFTD
PITVKFANTPNCIFVYNLAPETEESILWQLFGPFGAQNVKIIRDFQSQKC
KGFGFVTMTNYDEALMAINSLNGFTLGNRVLQVSFKTNK
>Dm-ELAV
TNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQQSLGYGFVNYVR
PQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQ
ELEAIFAPFGAIITSRILQNGVGFIRFDKREEATRAIIALNGTTPSSCTD
PIVVKFSNTPGPIFIYNLAPETEEAALWQLFGPFGAQSVKIVKDPTTNQC
KGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNK
>Hs-ELAVL1
TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAHSLGYGFVNYVT
AKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK
DVEDMFSRFGRIINSRVLVDGVAFIRFDKRSEAEEAITSFNGHKPPGSSE
PITVKFAANPNCIFIYNLGQDADEGILWQMFGPFGATNVKVIRDFNTNKC
KGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK
>Hs-ELAVL4
TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITQSLGYGFVNYID
PKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQK
ELEQLFSQYGRIITSRILVDGVGFIRFDKRIEAEEAIKGLNGQKPSGATE
PITVKFANNPSCIFVYNLSPDSDESVLWQLFGPFGANNVKVIRDFNTNKC
KGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK
>Hs-ELAVL3
TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITQSLGYGFVNYSD
PNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQK
EMEQLFSQYGRIITSRILVDGVGFIRFDKRIEAEEAIKGLNGQKPLGAAE
PITVKFANNPSCIFVYNLSPEADESVLWQLFGPFGATNVKVIRDFTTNKC
KGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSK
>Hs-ELAVL2
TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITQSLGYGFVNYID
PKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQK
ELEQLFSQYGRIITSRILVDGVGFIRFDKRIEAEEAIKGLNGQKPPGATE
PITVKFANNPSCIFVYNLAPDADESILWQMFGPFGATNVKVIRDFNTNKC
KGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK
>Dm-Fne
TNLIVNYLPQTMTQEEMRSLFSSIGELESCKLVRDKVSQSLGYGFVNYVR
AEDAEKAVNTLNGLRLQNKVIKVSYARPSSESIKGANLYVSGLPKNLSQP
DLEGMFASFGKIITSRILCDGVGFIRFDQRNEAERAIQELNGKTPKGYAE
PITVKFANNPSCIFVYNLAPETEENVLWQLFGPFGAQSVKVIRDLQTSKC
KGFGFVTMTNYDEAVVAIQSLNGYTLGNRVLQVSFKTNK
>Dm-Rbp9
TNLIVNYLPQTMSQDEIRSLFVSFGEVESCKLIRDKVTQSLGYGFVNYVK
QEDAEKAINALNGLRLQNKTIKVSIARPSSESIKGANLYVSGLPKNMTQS
DLESLFSPYGKIITSRILCDGVGFIRFDQRFEADRAIKELNGTTPKNSTE
PITVKFANNPSCIFVYNLAPDTEENVLWQLFGPFGAQSVKVIRDLQSNKC
KGFGFVTMTNYEEAVLAIQSLNGYTLGNRVLQVSFKTNK
>Dma-ELAV2
TNLIVNYLPQTMTQEEIRSLFASIGEVESCKLIRDKITQSLGYGFVNYHR
AEDAEKAINTLNGLRLQNKTIKVSFARPSSENIKGANLYVSGIPKTMCQS
ELETLFAPFGRIITSRILCDGVGFIRFDTRGEAERAIEKLNGTVPQGATE
PITVKFANNPSCIFVYNLAPDTEESVLWQLFGPFGAQSVKVIRDLQTNKC
KGFGFVTMTNYDEALVAIQSLNGYTLGNRVLQVSFKTAG
>Pt-ELAVL3
TNLIVNYLPQTMTQEEIRSLFSSIGEVESCKLIRDKVTQSLGYGFVNYVR
PEDAEKAINTLNGLRLQNKTIKVSYARPSSEAIKGANLYVSGLPKSMTQQ
DLEGLFTPFGRIITSRILCDGVGFVRFDQRIEAERAIKHLHNTIPDGASE
PITVKFANNPSCIFVYNLAPDTEENLLWQLFGPFGAQSVKVIRDLQTNKC
KGFGFVTMTNYDEALVAIQSLNGYTLGNRVLQVSFKTNK
>Pt-ELAVL1
TNLIVNYLPQTMTQEEIRSLFSSIGEVESCKLIRDKVTQSLGYGFVNYVR
PEDAEKAINTLNGLRLQNKTIKVSYARPSSEAIKGANLYVSGLPKAFTQQ
DLEAQFSPFGRIITSRILCDGVGFVRFDQRMEAERAIKHLNNTIPEGATD
PITVKFANNPSCIFVYNLAPDTEENLLWQLFGPFGAQSVKVIRDLQTNKC
KGFGFVTMTNYDEALVAIQSLNGYTLGNRVLQVSFKTNK
>Pd-ELAV
TNLIVNYLPQTMTQEEIRSLFSSIGEVESCKLIRDKATQSLGYGFVNYKR
PEDAEKAINTLNGLRLQNKTIKVSYARPSSESIKGANLYLSGLPKSMSEP
ELRSLFSSCGSIINCRILCDGVGFIRFDQRVEAERAIKQLNGKVPEGATE
PITVKFANAPSCIFVYNLAPETEENVLWQLFGPFGAQSVKVIRDFQTQKC
KGFGFVTMTNYDEALMAIQSLNGYTLGNRVLQVSFKTNN
>La-ELAVL3
TNLIVNYLPQTMTQEEIRSLFSSIGEVESCKLIRDKTTQSLGYGFVNYKS
PDDADKAISTLNGLRLQNKTIKVSVARPSCESIKGANLYISGLPKTMTQL
ELENLFSRCGSIITSRILSDGVGFIRFDQRHEAERAIKDLNGKIPEGSTE
AITVKFANSPSCIFVYNLAPETEENTLWQLFGPFGAQSVKVIRDFQSQKC
KGFGFVTMTNYEDSLMAIQSLNGFALGNRILQVSFKTNK
>Cg-ELAVL1
TNLIVNYLPQTMTQEEIRALFSSIGEVESCKLIRDKPTQSLGYGFVNYKN
PADAEKAINTLNGLRLQNKLIKVSLARPSCESIKGANLYISGLPKSLTQL
DLEKMFSDCGQIITSRILYDGVGFIRFDQRVEAERAIQKLNGTIPDGATE
PITVKFANSPSCIFVYNLAPETEDSTLWQLFGPFGAQNVKVIRDFQSQKC
KGFGFVTMTNYDESLMAIQSLNGFALGNRVLQVSFKTNK
>Sk-Hu/ELAV
TNLIINYLPQTMTQEEIKSLFSSIGEIESCKLIRDKVTQSLGYAFVNYHK
AADAEKAINTLNGLRLQAKTIKVSYARPSSQAIKDANLYVCGLPKTMAQK
DLEEMFTSCGRIITSRILCDGVGFIRFDKRTEAEEAIKRYNGTIPPGAVD
AITVKFANNPSCIFVYNLSPETEESLLWQLFGPFGATNVKVMRDFSTNKC
KGFGFVTMTNYDEAVVAIAXLNGYALGARVLQVSFKTNK

Figure 3A
>He-SO
FSSEQIAVVCEVLQRGGDIKRLGHFVWNLPESVLKARAQIAFATQEYKTL
YMILENHEFSQESHPELQKLWLKAHYNEQEKLRGRALGAVGKYRVRRKFP
LPRTIWDGEETSYCFKEKSRNHLREWYKTNQYPSPRDKKELAEMTGLTTT
QVSNWFKNRRQRDR
>He-SIX4
YSFDQIDCIVEVQLQCGNMKMLSAFLSAYTDMYKRAMAWLAFNHARFSEV
YSILETHSFLSCHHGELQDLWYQARYAEAEKARCRSLGAVDKYRLRRKFP
LPKTIWDGEETIYCFKEKSRLALKDCYKANRYPSPEEKRYLSQKTGLTIT
QVANWFKNRRQRDR
>He-SIX3
FSVDQVAHACETLEEAHDIERLHRFLWSLPESVLRAQATVCFFTGDYKGL
YVILENHKFGKEHHHKLQTMWLEAHYLDAEKLRGRALGPVDKYRVRKKYP
LPKTIWDGEQKTHCFKERTRHLLREWYLQDPYPNPTKKKELAQATNLTPT
QVGNWFKNRRQRDR
>Dm-SO
FTQEQVACVCEVLQQAGNIERLGRFLWSLPESVLKAKAVVAFHRGQYKEL
YRLLEHHHFSAQNHAKLQALWLKAHYVEAEKLRGRPLGAVGKYRVRRKFP
LPRTIWDGEETSYCFKEKSRSVLRDWYSHNPYPSPREKRDLAEATGLTTT
QVSNWFKNRRQRDR
>Dm-OPTIX
FSAAQVEIVCKTLEDSGDIERLARFLWSLPEAVLRARAVVAYHVGNFREL
YAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFP
LPPTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPT
QVGNWFKNRRQRDR
>Hs-SIX4
FSPDHVACVCEALQQGGNLDRLARFLWSLPESLLKARALVAFHQGIYPEL
YSILESHSFESANHPLLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFP
LPRTIWDGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLT
QVSNWFKNRRQRDR
>Dm-SIX4
FSTDQIQCMCEALQQKGDIEKLTTFLCSLPESVLRARAMVAYNLGQFHEL
YNLLETHCFSIKYHVDLQNLWFKAHYKEAEKVRGRPLGAVDKYRLRKKYP
LPKTIWDGEETVYCFKEKSRNALKDCYLTNRYPTPDEKKTLAKKTGLTLT
QVSNWFKNRRQRDR
>Hs-SIX1
FTQEQVACVCEVLQQGGNLERLGRFLWSLPESVLKAKAVVAFHRGNFREL
YKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFP
LPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTT
QVSNWFKNRRQRDR
>Hs-SIX2
FTQEQVACVCEVLQQGGNIERLGRFLWSLPESVLKAKAVVAFHRGNFREL
YKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFP
LPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTT
QVSNWFKNRRQRDR
>Hs-SIX3
FSPEQVASVCETLEETGDIERLGRFLWSLPESILRARAVVAFHTGNFRDL
YHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFP
LPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPT
QVGNWFKNRRQRDR
>Hs-SIX6
FSPQQVAGVCETLEESGDVERLGRFLWSLPESVLRARAIVAFHGGNYREL
YHILENHKFTKESHAKLQALWLEAHYQEAEKLRGRPLGPVDKYRVRKKFP
LPRTIWDGEQKTHCFKERTRHLLREWYLQDPYPNPSKKRELAQATGLTPT
QVGNWFKNRRQRDR
>Hs-SIX5
FSPEQVACVCEALLQAGHAGRLSRFLGALPDPVLRARALVAFQRGEYAEL
YRLLESRPFPAAHHAFLQDLYLRARYHEAERARGRALGAVDKYRLRKKFP
LPKTIWDGEETVYCFKERSRAALKACYRGNRYPTPDEKRRLATLTGLSLT
QVSNWFKNRRQRDR

Figure 5A
>Dm-OTD
KQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWF
KNRRAKCRQQ
>Mm-OTX1
KQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWF
KNRRAKCRQQ
>Sp-OTX
KQRRERTTFTRAQLDVLETLFSRTRYPDIFMREEVAMKINLPESRVQVWF
KNRRAKCRQQ
>Lg-OTX
KQRRERTTFTRAQLDVLESLFQKTRYPDIFMREEVALKINLPESRVQVWF
KNRRAKCRQQ
>Hs-ALX1
KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWF
QNRRAKWRKR
>Hs-ALX3
KKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWF
QNRRAKWRKR
>Hs-ALX4
KKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWF
QNRRAKWRKR
>Hs-HESX1
RGRRPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWF
QNRRAKLKRS
>Hs-ARX
KQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWF
QNRRAKWRKR
>Dm-AL
KQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWF
QNRRAKWRKQ
>Dm-PPH13
KQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWF
QNRRAKWRKQ
>Hs-ARIX
KQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWF
QNRRAKFRKQ
>Hs-PHOX2B
KQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWF
QNRRAKFRKQ
>Dm-PHDP
KQRRIRTTFTSNQLNELEKIFLETHYPDIYTREEIASKLHLTEARVQVWF
QNRRAKFRKQ
>Hs-CHX10
KKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWF
QNRRAKWRKR
>Hs-VSX1
KKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWF
QNRRAKWRKR
>Dm-VSX1
NKRRHRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWY
QNRRAKWRKT
>Hs-DMBX1
KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWF
KNRRAKFRKK
>Hs-DUX1
KGRRKRTAITGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWF
QNRRARHRGQ
>Hs-DUX3A
KGRRKRTAITGSQTALLLRAFEKDRFPGIPAREELARETGLPESRIQLWF
QNRRARHWGQ
>Hs-DUX5
KGRRKRTAITGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWF
QNRRARHRGQ
>Hs-GSC
RKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWF
KNRRAKWRRQ
>Dm-GSC
RKRRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWF
KNRRAKWRKQ
>Dm-HBN
KVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWF
QNRRAKWRKR
>Hs-MIXL1
SQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWF
QNRRAKSRRQ
>Hs-OTP
KQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWF
QNRRAKWKKR
>Dm-OTP
KQKRHRTRFTPAQLNELERCFSKTHYPDIFMREEIAMRIGLTESRVQVWF
QNRRAKWKKR
>Hs-OTX1
KQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWF
KNRRAKCRQQ
>Hs-OTX2
KQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWF
KNRRAKCRQQ
>Hs-CRX
KQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWF
KNRRAKCRQQ
>Hs-PAX3
KQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWF
SNRRARWRKQ
>Hs-PAX7
KQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF
SNRRARWRKQ
>Dm-GSB
KQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWF
SNRRARLRKQ
>Dm-GSBN
KQRRSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWF
SNRRARLRKH
>Dm-PRD
KQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWF
SNRRARLRKQ
>Hs-PAX4
TGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWF
SNRRAKWRRQ
>Hs-PAX6
KLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWF
SNRRAKWRRE
>Dm-EYG
KFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTSLSEARVQVWF
SNRRAKWRRH
>Dm-TOE
KFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWF
SNRRAKWRRH
>Dm-TOY
KLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWF
SNRRAKWRRE
>Dm-EY
KLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWF
SNRRAKWRRE
>Hs-PRRX1
KQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWF
QNRRAKFRRN
>Hs-PRRX2
KQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWF
QNRRAKFRRN
>Dm-CG9876
KPRRNRTTFSSAQLTALEKVFERTHYPDAFVREELATKVHLSEARVQVWF
QNRRAKFRRN
>Hs-PITX1
KQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWF
KNRRAKWRKR
>Hs-PITX2
RQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWF
KNRRAKWRKR
>Hs-PITX3
KQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWF
KNRRAKWRKR
>Dm-PTX1
RQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWF
KNRRAKWRKR
>Hs-RAX
KHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWF
QNRRAKWRRQ
>Hs-MGC15631
KHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWF
QNRRAKWRRQ
>Dm-RX
KHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWF
QNRRAKWRRQ
>Hs-SHOX
KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWF
QNRRAKCRKQ
>Hs-SHOX2
KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWF
QNRRAKCRKQ
>Dm-UNC-4
KRRRSRTNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWF
QNRRAKVRKR
>Dm-ODSH
KKRRGRTNFNSWQLRELERVFQGSHYPDIFMREALATKLDLMEGRIAVWF
QNRRAKWRKQ
>Hs-PROP1
SRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWF
QNRRAKQRKQ
>Dm-CG11294
RQRRNRTTFTPQQLQELEALFQKTHYPDVFLREEVALRISLSEARVQVWF
QNRRAKWRKQ
>Dm-CG32532
ARRRHRTTFTQEQLAELEAAFAKSHYPDIYCREELARTTKLNEARIQVWF
QNRRAKYRKQ
>He-AL
KQRRYRTTFTAFQLQELEKCFGKTHYPDIFTRDELAMRIHLTEARIQVWF
QNRRAKWRKT
>He-PHDP
KQRRIRTTFTSGQLKELERAFQETHYPDIYTREEIAAKIDLTEARVQVWF
QNRRAKFRKQ
>He-RX
KHRRNRTTFTTYQLHELERAFDKSHYPDVYAREELANRVSLPEVRVQVWF
QNRRAKWRRQ
>He-GSC
RKRRHRTIFTEEQLEYLEETFNKTHYPDVLLREELAVKVDLKEERVEVWF
KNRRAKYRKQ
>He-HBN
KIRRSRTTFTTYQLHQLEHAFEKTQYPDVFSREELAYRLDLSEARVQVWF
QNRRAKYRKR
>He-PRRX
QQRRNRTTFTTAQLTALEKVFEKTHYPDAFAREDIAKKVNLTEARVQVWF
QNRRAKFRRN
>He-PRD003
KQRRNRTTFTVQQLEELETAFAQTHYPDVFTREDLALKINLTEARVQVWF
QNRRAKWRKH
>He-VSX1
KKRRHRTIFTSYQIEELEKAFKEAHYPDVYAREMLSLKTDLPEDRIQVWF
QNRRAKWRKT
>He-PRD001
KQRRSRTAFTNQQLTTLEKTFAKTHYPDVGLREQLAHCTTLPESRIQVWF
KNRRAKNRKR
>He-PRD002
ARRRHRTTFTQDQLAELESAFAKSHYPDIYCREELARITKLNEARIQVWF
QNRRAKYRKQ
>He-SHOX
KQRRTRTNFTLEQLQSLERLFDETHYPDAFMRESISHKLQLSEARVQVWF
QNRRAKSRKQ
>He-UNC-4
KRRRTRTNFTGWQLQELERAFESSHYPDVFMREAVALRLDLAESRVQVWF
QNRRAKWRKK
>He-OTD
KQRRERTTFTRAQLDHLEQLFMNTRYPDIFMREEAAMKIGLPEPRVQVWF
KNRRAKVRQQ
>He-PAX6
KLQRNRTSFTNEQIEALEKVFAQTHYPDVYGREQLAEKVSLQEAKIQVWF
SNRRAKFRRE
>He-OTP
KQKRHRTRFTPAQLNELERSFAKTHYPDIFYREEIAMRIALTESRVQVWF
QNRRAKWKKR
>Dm-REPO
KKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWF
QNRRAKWRKH

Figure 7A
>An-POXM
FVNGRPLPRLRIVEMANLGVRPCDISRRLKVSHGCVSKILARYHETGSVL
PGAIGGSKPVTTPRVVGRIRDYKVKDPGMFAWEIREKLLLDNVCDKFNVP
SVSSISRILRNK
>An-PAX2/5/8
FVNGRPLPRQSIVELAKQGVRPCDISRQLRVSHGCVSKILGRFHETGSIR
PGIIGGSKPVATPKVVDAINNYKNQAPTMFAWEIRERLIADGICDADKVP
SVSSINRIVRNR
>He-PAX6
FVNGRPLSRQRIVEYAINGARPCDISRMLQVSNGCVSKILGRYYETGSIR
PRAIGGSKPVATDEVVRKVAVYKNETPAIFAWEIRDRLIQEQVCTQENIP
SVSSINRVLRNL
>He-SV
FVNGRPLPRNKIVDLAQQGVRPCDISRQLRVSHGCVSKILGRFYETGSIR
PGVIGGSKPVATPKVVDHIANYKRQNPTMFAWEIRDRLLNDNICDQDNIP
SVSSINRIVRNK
>He-POXN
FVNGRPLPRRKIVELACMGVRPCDISRQLLVSHGCVSKILTRYHETGSIK
PGSIGGSKPIATPLVIKKILHMKRENASIFAWEIRDILLLQRVCDIHSLP
SVSSINRILRTS
>He-POXM
FVNGRPLPRVRIIELANLGVRPCDISRQLRVSHGCVSKILARFNETGSIM
PGAIGGSKPVTTPKVVQHIRDLKHRDPGIFAWEIRDRLIHDGVCDKFSVP
SVSSISRILRNK
>He-PAXa
YLNGKPLPRQQILFLSLCGLRPCDISRQLLVSHGCVSKILTKYLETGTIL
PGCIGGSKPVTTPFIVSKIVDYKKQHQTLFAWEIREKLYYDGICPKDVLP
SVSSINRILRKA
>Dm-SV
FVNGRPLPRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFK
AGVIGGSKPVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVP
SVSSINRIVRNK
>Dm-TOY
YVNGRPLPRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIK
PRAIGGSKPVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIP
SVSSINRVLRNL
>Hs-PAX1
FVNGRPLPRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSIL
PGAIGGSKPVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVP
SVSSISRILRNK
>Hs-PAX6
FVNGRPLPRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR
PRAIGGSKPVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIP
SVSSINRVLRNL
>Hs-PAX4
FVNGRPLPRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE
PKGIGGSKPLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTP
SVSSINRVLRAL
>Hs-PAX2
FVNGRPLPRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIK
PGVIGGSKPVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVP
SVSSINRIIRTK
>Hs-PAX5
FVNGRPLPRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIK
PGVIGGSKPVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVP
SVSSINRIIRTK
>Hs-PAX7
FINGRPLPRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR
PGAIGGSKPVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVP
SVSSISRVLRIK
>Hs-PAX3
FINGRPLPRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR
PGAIGGSKPVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVP
SVSSISRILRSK
>Hs-PAX8
FVNGRPLPRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIR
PGVIGGSKPVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVP
SVSSINRIIRTK
>Hs-PAX9
FVNGRPLPRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSIL
PGAIGGSKPVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVP
SVSSISRILRNK
>Dm-PRD
FINGRPLPRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETGSIR
PGVIGGSKPIATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAP
SVSAISRLVRGR
>Dm-GSB
FINGRPLPRRQIVEMAAAGVRPCVISRQLRVSHGCVSKILNRFQETGSIR
PGVIGGSKPVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAP
SVSSISRLLRGS
>Dm-GSBN
FINGRPLPRLKIVEMAASGVRPCVISRQLRVSHGCVSKILNRYQETGSIR
PGVIGGSKPVTSPEIETRIDELRKENPSIFSWEIREKLIKEGFADPPSTS
SISRLLRGS
>Dm-POXM
FVNGRPLPRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSIL
PGAIGGSKPVTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVP
SVSSISRILRNK
>Dm-POXN
FVNGRPLPRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSIR
PGSIGGSKTVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVP
SISSINRILRNS
>Ek-PBY
MAAAGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGVIGGSKPVATPE
VEKRIEEFKDENPGIFSWEIRDRLIKEGICDRNSAPSVSSISRVLRGK
>Er-PAX6
FVNGRPLPRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR
PRAIGGSKPVATAEVVAKIAQFKRECPSIFAWEIRDRLLSEGVCTNDSIP
GVSSINRVLRNL
>Er-PAX2/5/8
FVNGRPLPRQRIVELAHNGVRPCDISRQLRVSHGCVSKILGRYYETGSIK
PGVIGGSKPVATPKVVDAIANYKKQNPTMFAWEIRDRLLADGICDQDNIP
SVSSINRIVRNK
>Ep-POXN
FVNGRPLPRRRIVELAHMGVRPCDISRQLLVSHGCVSKILTRYYETGSIK
PGAIGGSKPVATPLVVKKILSMKQENPSIFAWEIRDLLLAQRVCDEQSIP
SVSSINRILRNS
>Er-PAXa
FANGRPLPRERILQLAFYGLRPCDISRQLLVSHGCVSKILSRFAETGSIL
PGAIGGSKPVSTPLVIAKIGQYKRENASLFAWEIRERLLYEGICTKEALP
SVSSINRILRNT
>Er-POXM
FVNGRPLPRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSIL
PGAIGGSKPVTTPKVVQHIKELKQRDPGIFAWEIRDRLLADGICDKYNVP
SVSSISRILRNK
>Er-PAX3/7
FINGRPLPRLKIVEMAAAGIRPCVISRQLRVSHGCVSKILCRYQETGSIR
PGVIGGSKPVATPEVEKRIEEFKDENPGIFSWEIRDRLIKEGICDRNSAP
SVSSISRVLRGK

Figure 9A
>He-UNPG
KQRRRRTAFTSEQLLDLEREFTQKKYLTLTERAQIARSLKLSEVQVKIWF
QNKRAKWKRN
>He-CAD
TKDKYRVVYSDHQRIELEKEFFKNKYISVKRKAELARNLLLSERQVKIWF
QNRRAKERKQ
>He-EVE
PIRRYRTAFSRDQIGRLEKEFLRENYVSRPRRCELAASLNLPESTIKVWF
QNRRMKDKRQ
>He-EXEX
KTRRPRTAFTSQQLLELEKQFRTSKYLSRPRRYEVASTLMLTETQVKIWF
QNRRMKWKRS
>He-HOX3
GNKRARTAYTSAQLVELEKEFHFSKYLCRPRRIEMANQLILSERQIKIWF
QNRRMKHKKE
>He-FTZ
GNKRTRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHSLGLTERQIKIWF
QNRRMKYKKE
>He-DFD
ETKRQRTAYTRHQILELEKEFYYNRYLTRRRRIEIAHVLQLTERQIKIWF
QNRRMKWKKD
>He-LAB
SNGTGRTNFTIKQLTELEKEFQYNKYLTRAKRIEIANQLSLNETQVKIWF
QNRRMKQKKR
>He-ABD-B1
SMRKKRKPYTKYQNLELEKEYLYSTYITKQKRWELARNLQLTERQVKIWF
QNRRMKTKKH
>He-ABD-B2
SLRKKRKPYTKYQTVELEREYHANPYITKQKRWELARNLQLTERQVKIWF
QNRRMKAKKH
>He-BTN
KARKERTSFTKRQLTRLEQEFLKQNYLTRLRRYELAVTLDLSERQVKVWF
QNRRMKCKRT
>He-RO
KERRARTTFTSPQTQVLELEYRRSEYISRPRRYELATQLNLKEVQIKIWY
QNRRAKDKRI
>He-ANTP003
KSRKARTAFTDSQLQTLEKRFERQKYLSVQDRMELAASLSLSDAQVKCWF
QNRRTKWKRQ
>He-ANTP002
KQRKPRTAFTDQQLQLLEKSFEAQRYLSVQDRMELAAKLQLADSQVKCWF
QNRRTKWKRQ
>He-ANTP005
KRRRLRTVFSDKQLAALEVRFISQKYMSTVDRESMAKSLGLTQMQVKTWY
QNRRMRWKKA
>He-BSH
RRRKARTVFSDNQLNGLEKRFESQRYLSTPERVDLANLLSLSETQVKTWF
QNRRMKHKKL
>He-LMS
RRKRPRTAFTGTQIKTLEAEFEKNKYLSVVKRIELSKALGLSQQQLKVWY
QNRRTKWKRK
>He-DLL
KMRKPRTIYSSLQLQQLNKRFQRTQYLALPERADLAASLGLTQTQVKIWF
QNRRSKYKKI
>He-EMS
KPKRIRTAFSPSQLLRLEHAFEKNHYVVGTERKQLAQSLGLSETQVKIWF
QNRRTKHKRL
>He-ANTP006
KKPRPRTTFTVQQMAILEQHFRRQAYISGTQRLELARALNLSEAQVKVWW
QNRRIKERKV
>He-EN
EDKRPRTAFTQEQLNRLKMEFQENRYLTEKRRQDLANDLQLNESQIKIWF
QNKRAKLKKA
>He-HHEX
HKRKGGQVFSNDQTLDLEQKFKKQKYLNPAERKKLAKSLILSERQIKTWF
QNRRAKWRRS
>He-DBX
KIRRRRAVFSDIQRQKLEDQFLVQKYISKPDRKKLAESLGLKDSQVKVWF
QNRRMKWRNT
>He-H2.0
KKTWTRAVFSSLQRKGLERSFFAQQYISKKDRRKLAATLGLSDSQVRIWY
ANRRMKNKKT
>He-HMX
RRKKTRTVFSRSQVFQLESTFDLKRYLSSADRAALAASLNLSEQQIKIWF
QNRRNKWKRQ
>He-LB
KKRKSRTAFTNTQVFELEKRFLYQKYLSPADRDEIAQSLGLSNAQVITWF
QNRRAKLKRD
>He-DR
PNRKPRTPFTTQQLMALERKFKTKQYLSIAERAEFSCQLSLTETQVKIWF
QNRRAKSKRL
>He-NKX2C
QRRKPRVLFSQAQVHELERRFKGMKYLSAPERDALAQHLKLTPQQVKIWY
QNRRYKCKRQ
>He-VND
KKRKRRVLFTKAQTIELERRFRTHKYLSAPEREHLASIIRLSPTQVKIWF
QNHRYKTKRS
>He-NKX2-1
TRRKRRVLFSQAQVTHLETRFKSTKYLSAPEREQLSHHIGLTPTQVKIWF
QNHRYKMKRQ
>He-BAP
RKKRSRAAFSHAQVFELERRFNHQRYLSGPERAELAAALTLTETQIKIWF
QNRRYKTKRK
>He-HGTX
GKKNTRPTFSGHQIFALEKTFEQTKYLAGPERAKLAFALGMSESQVKVWF
QNRRTKHRKR
>He-C15
KRKKPRTSFTRIQICELEKRFHRQKYLASAERASLAKSLKMTDAQVKTWF
QNRRTKHRRQ
>He-ANTP004
FQRRRRTAFSRAQLTFLEGKFQCQKYLTLSDRSQVADILSLTEAQVKCWF
QNRRTKWKRQ
>He-ANTP001
FDRKPRQAYTTKQLERLESEFRMDKYLTVSKRIDLADLLDLTEAQVKTWF
QNRRTKWKKQ
>Dm-UNPG
KSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWF
QNRRAKWKRV
>Hs-GBX1
KSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWF
QNRRAKWKRI
>Hs-GBX2
KNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWF
QNRRAKWKRV
>Dm-CAD
TKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWF
QNRRAKERKQ
>Hs-CDX1
TKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWF
QNRRAKERKV
>Hs-CDX2
TKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWF
QNRRAKERKI
>Hs-CDX4
TKEKYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWF
QNRRAKERKM
>Dm-EVE
SVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWF
QNRRMKDKRQ
>Hs-EVX2
QVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWF
QNRRMKDKRQ
>Dm-EXEX
KTRRPRTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWF
QNRRMKWKRS
>Hs-MNX1
KCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWF
QNRRMKWKRS
>Dm-IND
SSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWF
QNRRVKQKKG
>Hs-GSX1
SSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWF
QNRRVKHKKE
>Hs-GSX2
NGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWF
QNRRVKHKKE
>Dm-LAB
TNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWF
QNRRMKQKKR
>Hs-HOXA1
QPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWF
QNRRMKQKKR
>Hs-HOXB1
SPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWF
QNRRMKQKKR
>Hs-HOXD1
PSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWF
QNRRMKQKKR
>Dm-PB
LPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWF
QNRRMKHKRQ
>Hs-HOXA2
GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWF
QNRRMKHKRQ
>Hs-HOXB2
GARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWF
QNRRMKHKRQ
>Dm-ZEN
KLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWF
QNRRMKFKKD
>Hs-HOXA3
SSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWF
QNRRMKYKKD
>Hs-HOXB3
ASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWF
QNRRMKYKKD
>Hs-HOXD3
ASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWF
QNRRMKYKKD
>Dm-DFD
EPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWF
QNRRMKWKKD
>Hs-HOXA4
EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWF
QNRRMKWKKD
>Hs-HOXB4
EPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWF
QNRRMKWKKD
>Hs-HOXC4
EPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWF
QNRRMKWKKD
>HS-HOXD4
EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWF
QNRRMKWKKD
>Hs-HOXA5
EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWF
QNRRMKWKKD
>Hs-HOXB5
DGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWF
QNRRMKWKKD
>Hs-HOXC5
DGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWF
QNRRMKWKKD
>Dm-SCR
ETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWF
QNRRMKWKKE
>Hs-HOXA6
HGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWF
QNRRMKWKKE
>Hs-HOXB6
SGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWF
QNRRMKWKKE
>Hs-HOXC6
DRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWF
QNRRMKWKKE
>Hs-HOXA7
DRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWF
QNRRMKWKKE
>Hs-HOXB7
DRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWF
QNRRMKWKKE
>Hs-HOXB8
GRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWF
QNRRMKWKKE
>Hs-HOXC8
GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWF
QNRRMKWKKE
>Hs-HOXD8
GRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWF
QNRRMKWKKE
>Dm-ANTP
ERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWF
QNRRMKWKKE
>Dm-UBX
LRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWF
QNRRMKLKKE
>Dm-ABD-A
PRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWF
QNRRMKLKKE
>Hs-HOXA9
STRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWF
QNRRMKMKKI
>Hs-HOXB9
SSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWF
QNRRMKMKKM
>Hs-HOXC9
STRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWF
QNRRMKMKKM
>Hs-HOXD9
STRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWF
QNRRMKMKKM
>Hs-HOXA10
SGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWF
QNRRMKLKKM
>Hs-HOXA11
RTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWF
QNRRMKEKKI
>Hs-HOXC11
RTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWF
QNRRMKEKKL
>Hs-HOXD11
RSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWF
QNRRMKEKKL
>Hs-HOXC12
RSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWF
QNRRMKKKRL
>Hs-HOXD12
RARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWF
QNRRMKKKRV
>Hs-HOXA13
RGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWF
QNRRVKEKKV
>Hs-HOXB13
RGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWF
QNRRVKEKKV
>Hs-HOXC13
RGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWF
QNRRVKEKKV
>Hs-HOXD13
RGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWF
QNRRVKDKKI
>Dm-ABD-B
SVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWF
QNRRMKNKKN
>Hs-PDX1
ENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWF
QNRRMKWKKE
>Ct-XLOX
ENKRTRTAYTRAQLLELEKEFHFNRYITRPRRVELAAHLNLTEQHIKIWF
QNRRMKWKKD
>Hs-MEOX1
KARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWF
QNRRMKWKRV
>Hs-MEOX2
KPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWF
QNRRMKWKRV
>Dm-BTN
SNRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWF
QNRRMKCKRI
>Dm-RO
RQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWF
QNRRAKDKRI
>Dm-FTZ
DSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWF
QNRRMKSKKD
>Hs-BARHL1
KPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWY
QNRRTKWKRQ
>Hs-BARHL2
KPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWY
QNRRTKWKRQ
>Dm-BH-2
KQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWY
QNRRTKWKRQ
>Hs-BARX1
KGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWY
QNRRMKWKKI
>Hs-BARX2
KPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWY
QNRRMKWKKM
>Hs-BSX
RRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWF
QNRRMKHKKQ
>Dm-BSH
RRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWF
QNRRMKHKKQ
>Dm-LMS
RKKRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWF
QNRRTKWKRK
>Dm-DLL
KMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWF
QNRRSKYKKM
>Hs-DLX1
KIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWF
QNKRSKFKKL
>Hs-DLX2
KVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWF
QNRRSKFKKM
>Hs-DLX3
KVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWF
QNRRSKFKKL
>Hs-DLX4
KLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWF
QNKRSKYKKL
>Hs-DLX5
KVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWF
QNKRSKIKKI
>Hs-DLX6
KIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWF
QNKRSKFKKL
>Hs-EMX1
KPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWF
QNRRTKYKRQ
>Hs-EMX2
KPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWF
QNRRTKFKRQ
>Dm-EMS
KPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWF
QNRRTKHKRM
>Dm-E5
KPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWF
QNRRTKHKRM
>Dm-CG18599
KNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWF
QNRRIKWRKH
>Hs-EN1
EDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWF
QNKRAKIKKA
>Hs-EN2
EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWF
QNKRAKIKKA
>Dm-EN
DEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWF
QNKRAKIKKS
>Hs-HHEX
KRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWF
QNRRAKWRRL
>Dm-HHEX
KRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWF
QNRRAKWRRA
>Hs-HLX
KRKRSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWF
QNRRMKWRHS
>Hs-DBX2
KARRRRAVFSEDQRKALEKMFQKQKYISKTDRKKLAINLGLKESQVKIWF
QNRRMKWRNS
>Dm-DBX
RGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWF
QNRRMKWRNS
>Dm-H2.0
KRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWF
QNRRMKWRHT
>Hs-HMX1
RKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWF
QNRRNKWKRQ
>Hs-HMX2
AKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWF
QNRRNKWKRQ
>Hs-HMX3
RKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWF
QNRRNKWKRQ
>Dm-HMX
RKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWF
QNRRNKWKRQ
>Hs-LBX1
KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWF
QNRRAKLKRD
>Hs-LBX2
KRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWF
QNRRAKLKRD
>Dm-LBE
KKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWF
QNRRAKQKRD
>Dm-LBL
KKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWF
QNRRAKLKRD
>Hs-MSX1
TNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWF
QNRRAKAKRL
>Hs-MSX2
TNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWF
QNRRAKAKRL
>Dm-DR
PNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWF
QNRRAKAKRL
>Dm-CG15696
PGRLPRIPFTPQQLQALENAYKESNYLSAEDANKLADSLELTNTRVKIWF
QNRRARERRE
>Hs-NKX1-2
KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWF
QNRRTKWKKQ
>Dm-SLOU
KPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWF
QNRRTKWKKQ
>Hs-NKX2-5
RRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWF
QNRRYKCKRQ
>Hs-NKX2-6
QRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWF
QNRRYKCKRQ
>Hs-NKX2-2
KKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWF
QNHRYKMKRA
>Hs-NKX2-3
SRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWF
QNRRYKCKRQ
>Hs-NKX2-8
KRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWF
QNHRYKLKRA
>Hs-NKX2-1
PRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWF
QNHRYKMKRQ
>Dm-TIN
MKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWF
QNRRYKSKRG
>Dm-VND
KKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWF
QNHRYKTKRA
>Hs-NKX3-1
PQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWF
QNRRYKKRKQ
>Hs-NKX3-2
RKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWF
QNRRYKKRRQ
>Dm-BAP
RKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWF
QNRRYKKRKQ
>Hs-NKX6-1
KRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWF
QNRRTKWRKK
>Hs-NKX6-2
KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWF
QNRRTKWRKR
>Dm-HGTX
KKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWF
QNRRTKWRKR
>Dm-NK7.1
RKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWF
QNRRTKWKKQ
>Hs-TLX1
KKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWF
QNRRTKWRRQ
>Hs-TLX2
KRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWF
QNRRTKWRRQ
>Hs-TLX3
KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWF
QNRRTKWRRQ
>Dm-C15
KRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWF
QNRRTKWRRQ
>Hs-VAX2
RPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWF
QNRRTKQKKD
>Hs-NANOG
KKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWF
QNQRMKSKRW
>Hs-VENTX2
RAPRVRTAFTMEQVRTLEGVFQHHQYLSPLERKRLAREMQLSEVQIKTWF
QNRRMKHKRQ