ingest cdrApp 2018-03-15T16:27:55.954Z d591f2cd-3da7-4b31-9dd8-ee27dcb6a3ee modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-03-15T16:28:46.549Z Setting exclusive relation addDatastream MD_TECHNICAL fedoraAdmin 2018-03-15T16:28:57.529Z Adding technical metadata derived by FITS addDatastream MD_FULL_TEXT fedoraAdmin 2018-03-15T16:29:20.315Z Adding full text metadata extracted by Apache Tika modifyDatastreamByValue RELS-EXT fedoraAdmin 2018-03-15T16:29:42.473Z Setting exclusive relation modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-05-17T16:10:11.253Z modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-07-11T02:52:20.778Z modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-07-17T23:11:45.796Z modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-08-15T19:21:14.363Z modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-09-21T19:41:58.679Z modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-09-26T23:04:49.350Z modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2018-10-11T23:34:01.123Z modifyDatastreamByValue MD_DESCRIPTIVE cdrApp 2019-03-20T17:25:43.389Z Nadia Nguyen Author Department of Epidemiology Gillings School of Global Public Health Sexual partner type and risk of incident HIV infection among adolescent girls and young women in rural South Africa Adolescent girls and young women (AGYW) in South Africa face an unparalleled HIV burden and are a key population in need of intervention. Sexual partners play a critical role in HIV transmission by exposing young women to HIV and by encouraging risk behaviors that increase the risk of infection. However, sexual partners have not been well characterized, and approaches that use pre-specified labels to categorize partners into main versus casual types may not capture important differences between sexual partner types that increase AGYW’s risk of HIV infection. Thus, the overall goal of this dissertation was to develop a better understanding of the different types of sexual partners among AGYW in rural South Africa, identify which partner types pose the greatest risk for HIV infection among AGYW, and identify AGYW-level risk factors which predict partner selection. We followed 1034 AGYW enrolled in a randomized controlled trial in South Africa and used latent class analysis (LCA) to identify sexual partner types based on reported partner sociodemographic and behavioral risk factors from 2968 reported partners over three years of follow up. We identified six, distinct sexual partner types, which differed by age, school enrollment, concurrency, condom use, transactional sex, perceived HIV-status, and other risk factors. AGYW applied the label main partner/boyfriend broadly to describe a wide variety of partner types identified by LCA. Partner types identified by LCA strongly predicted incident HIV infection among AGYW, while partner types based on pre-specified labels were not significantly associated with HIV infection. AGYW who were not enrolled in school, reported high risk sexual behaviors (young age at first sex and multiple sexual partners in the past year), and reported substance use were more likely to select high risk sexual partners associated with increased risk of HIV infection compared to AGYW who did not report these behaviors. These results highlight the limitations of the main versus casual distinction as a proxy measure for other sociodemographic and behavioral differences between partners. Partner types based on explicit, reported partner characteristics offer an alternative model for measuring and targeting specific partner types for HIV research and intervention. Winter 2017 2017 Public health Adolescent girls and young women, HIV, Latent class analysis, Sexual partners, South Africa eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Epidemiology Audrey Pettifor Thesis advisor William Miller Thesis advisor Kimberly Powers Thesis advisor Annie Green-Howard Thesis advisor Carolyn Halpern Thesis advisor text Nadia Nguyen Creator Department of Epidemiology Gillings School of Global Public Health Sexual partner type and risk of incident HIV infection among adolescent girls and young women in rural South Africa Adolescent girls and young women (AGYW) in South Africa face an unparalleled HIV burden and are a key population in need of intervention. Sexual partners play a critical role in HIV transmission by exposing young women to HIV and by encouraging risk behaviors that increase the risk of infection. However, sexual partners have not been well characterized, and approaches that use pre-specified labels to categorize partners into main versus casual types may not capture important differences between sexual partner types that increase AGYW’s risk of HIV infection. Thus, the overall goal of this dissertation was to develop a better understanding of the different types of sexual partners among AGYW in rural South Africa, identify which partner types pose the greatest risk for HIV infection among AGYW, and identify AGYW-level risk factors which predict partner selection. We followed 1034 AGYW enrolled in a randomized controlled trial in South Africa and used latent class analysis (LCA) to identify sexual partner types based on reported partner sociodemographic and behavioral risk factors from 2968 reported partners over three years of follow up. We identified six, distinct sexual partner types, which differed by age, school enrollment, concurrency, condom use, transactional sex, perceived HIV-status, and other risk factors. AGYW applied the label main partner/boyfriend broadly to describe a wide variety of partner types identified by LCA. Partner types identified by LCA strongly predicted incident HIV infection among AGYW, while partner types based on pre-specified labels were not significantly associated with HIV infection. AGYW who were not enrolled in school, reported high risk sexual behaviors (young age at first sex and multiple sexual partners in the past year), and reported substance use were more likely to select high risk sexual partners associated with increased risk of HIV infection compared to AGYW who did not report these behaviors. These results highlight the limitations of the main versus casual distinction as a proxy measure for other sociodemographic and behavioral differences between partners. Partner types based on explicit, reported partner characteristics offer an alternative model for measuring and targeting specific partner types for HIV research and intervention. 2017-12 2017 Public health Adolescent girls and young women, HIV, Latent class analysis, Sexual partners, South Africa eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Epidemiology Audrey Pettifor Thesis advisor William Miller Thesis advisor Kimberly Powers Thesis advisor Annie Green-Howard Thesis advisor Carolyn Halpern Thesis advisor text Nadia Nguyen Creator Department of Epidemiology Gillings School of Global Public Health Sexual partner type and risk of incident HIV infection among adolescent girls and young women in rural South Africa Adolescent girls and young women (AGYW) in South Africa face an unparalleled HIV burden and are a key population in need of intervention. Sexual partners play a critical role in HIV transmission by exposing young women to HIV and by encouraging risk behaviors that increase the risk of infection. However, sexual partners have not been well characterized, and approaches that use pre-specified labels to categorize partners into main versus casual types may not capture important differences between sexual partner types that increase AGYW’s risk of HIV infection. Thus, the overall goal of this dissertation was to develop a better understanding of the different types of sexual partners among AGYW in rural South Africa, identify which partner types pose the greatest risk for HIV infection among AGYW, and identify AGYW-level risk factors which predict partner selection. We followed 1034 AGYW enrolled in a randomized controlled trial in South Africa and used latent class analysis (LCA) to identify sexual partner types based on reported partner sociodemographic and behavioral risk factors from 2968 reported partners over three years of follow up. We identified six, distinct sexual partner types, which differed by age, school enrollment, concurrency, condom use, transactional sex, perceived HIV-status, and other risk factors. AGYW applied the label main partner/boyfriend broadly to describe a wide variety of partner types identified by LCA. Partner types identified by LCA strongly predicted incident HIV infection among AGYW, while partner types based on pre-specified labels were not significantly associated with HIV infection. AGYW who were not enrolled in school, reported high risk sexual behaviors (young age at first sex and multiple sexual partners in the past year), and reported substance use were more likely to select high risk sexual partners associated with increased risk of HIV infection compared to AGYW who did not report these behaviors. These results highlight the limitations of the main versus casual distinction as a proxy measure for other sociodemographic and behavioral differences between partners. Partner types based on explicit, reported partner characteristics offer an alternative model for measuring and targeting specific partner types for HIV research and intervention. 2017-12 2017 Public health Adolescent girls and young women, HIV, Latent class analysis, Sexual partners, South Africa eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Epidemiology Audrey Pettifor Thesis advisor William Miller Thesis advisor Kimberly Powers Thesis advisor Annie Green-Howard Thesis advisor Carolyn Halpern Thesis advisor text Nadia Nguyen Creator Department of Epidemiology Gillings School of Global Public Health Sexual partner type and risk of incident HIV infection among adolescent girls and young women in rural South Africa Adolescent girls and young women (AGYW) in South Africa face an unparalleled HIV burden and are a key population in need of intervention. Sexual partners play a critical role in HIV transmission by exposing young women to HIV and by encouraging risk behaviors that increase the risk of infection. However, sexual partners have not been well characterized, and approaches that use pre-specified labels to categorize partners into main versus casual types may not capture important differences between sexual partner types that increase AGYW’s risk of HIV infection. Thus, the overall goal of this dissertation was to develop a better understanding of the different types of sexual partners among AGYW in rural South Africa, identify which partner types pose the greatest risk for HIV infection among AGYW, and identify AGYW-level risk factors which predict partner selection. We followed 1034 AGYW enrolled in a randomized controlled trial in South Africa and used latent class analysis (LCA) to identify sexual partner types based on reported partner sociodemographic and behavioral risk factors from 2968 reported partners over three years of follow up. We identified six, distinct sexual partner types, which differed by age, school enrollment, concurrency, condom use, transactional sex, perceived HIV-status, and other risk factors. AGYW applied the label main partner/boyfriend broadly to describe a wide variety of partner types identified by LCA. Partner types identified by LCA strongly predicted incident HIV infection among AGYW, while partner types based on pre-specified labels were not significantly associated with HIV infection. AGYW who were not enrolled in school, reported high risk sexual behaviors (young age at first sex and multiple sexual partners in the past year), and reported substance use were more likely to select high risk sexual partners associated with increased risk of HIV infection compared to AGYW who did not report these behaviors. These results highlight the limitations of the main versus casual distinction as a proxy measure for other sociodemographic and behavioral differences between partners. Partner types based on explicit, reported partner characteristics offer an alternative model for measuring and targeting specific partner types for HIV research and intervention. 2017-12 2017 Public health Adolescent girls and young women, HIV, Latent class analysis, Sexual partners, South Africa eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Epidemiology Audrey Pettifor Thesis advisor William Miller Thesis advisor Kimberly Powers Thesis advisor Annie Green-Howard Thesis advisor Carolyn Halpern Thesis advisor text Nadia Nguyen Creator Department of Epidemiology Gillings School of Global Public Health Sexual partner type and risk of incident HIV infection among adolescent girls and young women in rural South Africa Adolescent girls and young women (AGYW) in South Africa face an unparalleled HIV burden and are a key population in need of intervention. Sexual partners play a critical role in HIV transmission by exposing young women to HIV and by encouraging risk behaviors that increase the risk of infection. However, sexual partners have not been well characterized, and approaches that use pre-specified labels to categorize partners into main versus casual types may not capture important differences between sexual partner types that increase AGYW’s risk of HIV infection. Thus, the overall goal of this dissertation was to develop a better understanding of the different types of sexual partners among AGYW in rural South Africa, identify which partner types pose the greatest risk for HIV infection among AGYW, and identify AGYW-level risk factors which predict partner selection. We followed 1034 AGYW enrolled in a randomized controlled trial in South Africa and used latent class analysis (LCA) to identify sexual partner types based on reported partner sociodemographic and behavioral risk factors from 2968 reported partners over three years of follow up. We identified six, distinct sexual partner types, which differed by age, school enrollment, concurrency, condom use, transactional sex, perceived HIV-status, and other risk factors. AGYW applied the label main partner/boyfriend broadly to describe a wide variety of partner types identified by LCA. Partner types identified by LCA strongly predicted incident HIV infection among AGYW, while partner types based on pre-specified labels were not significantly associated with HIV infection. AGYW who were not enrolled in school, reported high risk sexual behaviors (young age at first sex and multiple sexual partners in the past year), and reported substance use were more likely to select high risk sexual partners associated with increased risk of HIV infection compared to AGYW who did not report these behaviors. These results highlight the limitations of the main versus casual distinction as a proxy measure for other sociodemographic and behavioral differences between partners. Partner types based on explicit, reported partner characteristics offer an alternative model for measuring and targeting specific partner types for HIV research and intervention. 2017-12 2017 Public health Adolescent girls and young women, HIV, Latent class analysis, Sexual partners, South Africa eng Doctor of Philosophy Dissertation Epidemiology Audrey Pettifor Thesis advisor William Miller Thesis advisor Kimberly Powers Thesis advisor Annie Green-Howard Thesis advisor Carolyn Halpern Thesis advisor text University of North Carolina at Chapel Hill Degree granting institution Nadia Nguyen Creator Department of Epidemiology Gillings School of Global Public Health Sexual partner type and risk of incident HIV infection among adolescent girls and young women in rural South Africa Adolescent girls and young women (AGYW) in South Africa face an unparalleled HIV burden and are a key population in need of intervention. Sexual partners play a critical role in HIV transmission by exposing young women to HIV and by encouraging risk behaviors that increase the risk of infection. However, sexual partners have not been well characterized, and approaches that use pre-specified labels to categorize partners into main versus casual types may not capture important differences between sexual partner types that increase AGYW’s risk of HIV infection. Thus, the overall goal of this dissertation was to develop a better understanding of the different types of sexual partners among AGYW in rural South Africa, identify which partner types pose the greatest risk for HIV infection among AGYW, and identify AGYW-level risk factors which predict partner selection. We followed 1034 AGYW enrolled in a randomized controlled trial in South Africa and used latent class analysis (LCA) to identify sexual partner types based on reported partner sociodemographic and behavioral risk factors from 2968 reported partners over three years of follow up. We identified six, distinct sexual partner types, which differed by age, school enrollment, concurrency, condom use, transactional sex, perceived HIV-status, and other risk factors. AGYW applied the label main partner/boyfriend broadly to describe a wide variety of partner types identified by LCA. Partner types identified by LCA strongly predicted incident HIV infection among AGYW, while partner types based on pre-specified labels were not significantly associated with HIV infection. AGYW who were not enrolled in school, reported high risk sexual behaviors (young age at first sex and multiple sexual partners in the past year), and reported substance use were more likely to select high risk sexual partners associated with increased risk of HIV infection compared to AGYW who did not report these behaviors. These results highlight the limitations of the main versus casual distinction as a proxy measure for other sociodemographic and behavioral differences between partners. Partner types based on explicit, reported partner characteristics offer an alternative model for measuring and targeting specific partner types for HIV research and intervention. 2017-12 2017 Public health Adolescent girls and young women, HIV, Latent class analysis, Sexual partners, South Africa eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Epidemiology Audrey Pettifor Thesis advisor William Miller Thesis advisor Kimberly Powers Thesis advisor Annie Green-Howard Thesis advisor Carolyn Halpern Thesis advisor text Nadia Nguyen Creator Department of Epidemiology Gillings School of Global Public Health Sexual partner type and risk of incident HIV infection among adolescent girls and young women in rural South Africa Adolescent girls and young women (AGYW) in South Africa face an unparalleled HIV burden and are a key population in need of intervention. Sexual partners play a critical role in HIV transmission by exposing young women to HIV and by encouraging risk behaviors that increase the risk of infection. However, sexual partners have not been well characterized, and approaches that use pre-specified labels to categorize partners into main versus casual types may not capture important differences between sexual partner types that increase AGYW’s risk of HIV infection. Thus, the overall goal of this dissertation was to develop a better understanding of the different types of sexual partners among AGYW in rural South Africa, identify which partner types pose the greatest risk for HIV infection among AGYW, and identify AGYW-level risk factors which predict partner selection. We followed 1034 AGYW enrolled in a randomized controlled trial in South Africa and used latent class analysis (LCA) to identify sexual partner types based on reported partner sociodemographic and behavioral risk factors from 2968 reported partners over three years of follow up. We identified six, distinct sexual partner types, which differed by age, school enrollment, concurrency, condom use, transactional sex, perceived HIV-status, and other risk factors. AGYW applied the label main partner/boyfriend broadly to describe a wide variety of partner types identified by LCA. Partner types identified by LCA strongly predicted incident HIV infection among AGYW, while partner types based on pre-specified labels were not significantly associated with HIV infection. AGYW who were not enrolled in school, reported high risk sexual behaviors (young age at first sex and multiple sexual partners in the past year), and reported substance use were more likely to select high risk sexual partners associated with increased risk of HIV infection compared to AGYW who did not report these behaviors. These results highlight the limitations of the main versus casual distinction as a proxy measure for other sociodemographic and behavioral differences between partners. Partner types based on explicit, reported partner characteristics offer an alternative model for measuring and targeting specific partner types for HIV research and intervention. 2017-12 2017 Public health Adolescent girls and young women; HIV; Latent class analysis; Sexual partners; South Africa eng Doctor of Philosophy Dissertation Epidemiology Audrey Pettifor Thesis advisor William Miller Thesis advisor Kimberly Powers Thesis advisor Annie Green-Howard Thesis advisor Carolyn Halpern Thesis advisor text University of North Carolina at Chapel Hill Degree granting institution Nadia Nguyen Creator Department of Epidemiology Gillings School of Global Public Health Sexual partner type and risk of incident HIV infection among adolescent girls and young women in rural South Africa Adolescent girls and young women (AGYW) in South Africa face an unparalleled HIV burden and are a key population in need of intervention. Sexual partners play a critical role in HIV transmission by exposing young women to HIV and by encouraging risk behaviors that increase the risk of infection. However, sexual partners have not been well characterized, and approaches that use pre-specified labels to categorize partners into main versus casual types may not capture important differences between sexual partner types that increase AGYW’s risk of HIV infection. Thus, the overall goal of this dissertation was to develop a better understanding of the different types of sexual partners among AGYW in rural South Africa, identify which partner types pose the greatest risk for HIV infection among AGYW, and identify AGYW-level risk factors which predict partner selection. We followed 1034 AGYW enrolled in a randomized controlled trial in South Africa and used latent class analysis (LCA) to identify sexual partner types based on reported partner sociodemographic and behavioral risk factors from 2968 reported partners over three years of follow up. We identified six, distinct sexual partner types, which differed by age, school enrollment, concurrency, condom use, transactional sex, perceived HIV-status, and other risk factors. AGYW applied the label main partner/boyfriend broadly to describe a wide variety of partner types identified by LCA. Partner types identified by LCA strongly predicted incident HIV infection among AGYW, while partner types based on pre-specified labels were not significantly associated with HIV infection. AGYW who were not enrolled in school, reported high risk sexual behaviors (young age at first sex and multiple sexual partners in the past year), and reported substance use were more likely to select high risk sexual partners associated with increased risk of HIV infection compared to AGYW who did not report these behaviors. These results highlight the limitations of the main versus casual distinction as a proxy measure for other sociodemographic and behavioral differences between partners. Partner types based on explicit, reported partner characteristics offer an alternative model for measuring and targeting specific partner types for HIV research and intervention. 2017-12 2017 Public health Adolescent girls and young women, HIV, Latent class analysis, Sexual partners, South Africa eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Epidemiology Audrey Pettifor Thesis advisor William Miller Thesis advisor Kimberly Powers Thesis advisor Annie Green-Howard Thesis advisor Carolyn Halpern Thesis advisor text Nadia Nguyen Creator Department of Epidemiology Gillings School of Global Public Health Sexual partner type and risk of incident HIV infection among adolescent girls and young women in rural South Africa Adolescent girls and young women (AGYW) in South Africa face an unparalleled HIV burden and are a key population in need of intervention. Sexual partners play a critical role in HIV transmission by exposing young women to HIV and by encouraging risk behaviors that increase the risk of infection. However, sexual partners have not been well characterized, and approaches that use pre-specified labels to categorize partners into main versus casual types may not capture important differences between sexual partner types that increase AGYW’s risk of HIV infection. Thus, the overall goal of this dissertation was to develop a better understanding of the different types of sexual partners among AGYW in rural South Africa, identify which partner types pose the greatest risk for HIV infection among AGYW, and identify AGYW-level risk factors which predict partner selection. We followed 1034 AGYW enrolled in a randomized controlled trial in South Africa and used latent class analysis (LCA) to identify sexual partner types based on reported partner sociodemographic and behavioral risk factors from 2968 reported partners over three years of follow up. We identified six, distinct sexual partner types, which differed by age, school enrollment, concurrency, condom use, transactional sex, perceived HIV-status, and other risk factors. AGYW applied the label main partner/boyfriend broadly to describe a wide variety of partner types identified by LCA. Partner types identified by LCA strongly predicted incident HIV infection among AGYW, while partner types based on pre-specified labels were not significantly associated with HIV infection. AGYW who were not enrolled in school, reported high risk sexual behaviors (young age at first sex and multiple sexual partners in the past year), and reported substance use were more likely to select high risk sexual partners associated with increased risk of HIV infection compared to AGYW who did not report these behaviors. These results highlight the limitations of the main versus casual distinction as a proxy measure for other sociodemographic and behavioral differences between partners. Partner types based on explicit, reported partner characteristics offer an alternative model for measuring and targeting specific partner types for HIV research and intervention. 2017-12 2017 Public health Adolescent girls and young women; HIV; Latent class analysis; Sexual partners; South Africa eng Doctor of Philosophy Dissertation University of North Carolina at Chapel Hill Graduate School Degree granting institution Audrey Pettifor Thesis advisor William Miller Thesis advisor Kimberly Powers Thesis advisor Annie Green-Howard Thesis advisor Carolyn Halpern Thesis advisor text Nguyen_unc_0153D_17381.pdf uuid:5f7fed37-5bae-4ffd-8ee8-9389e1d58ec2 2019-12-31T00:00:00 2017-10-28T03:07:16Z proquest application/pdf 2112243