Feasibility and initial efficacy of a culturally sensitive women-centered substance use intervention in Georgia: Sex risk outcomes

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  • Jones, Hendrée E
    • Affiliation: School of Medicine, Department of Obstetrics and Gynecology
    • Other Affiliation: Departments of Psychiatry and Behavioral Sciences and Obstetrics and Gynecology, School of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
  • Kirtadze, Irma
    • Other Affiliation: Addiction Research Center, Alternative Georgia, Tbilisi 0177, Georgia; Ilia State University, Business School, Tbilisi 0162, Georgia
  • Otiashvili, David
    • Other Affiliation: Addiction Research Center, Alternative Georgia, Tbilisi 0177, Georgia
  • Murphy, Keryn
    • Affiliation: School of Medicine, Department of Obstetrics and Gynecology
  • O’Grady, Kevin E
    • Other Affiliation: Department of Psychology, University of Maryland, College Park, College Park, MD 20742, USA
  • Zule, William
    • Other Affiliation: Substance Abuse Treatment Evaluations and Interventions Research Program, RTI International, Research Triangle Park, NC 27709, USA
  • Krupitsky, Evgeny
    • Other Affiliation: Department of Addictions, Bekhterev Research Psychoneurological Institute, St. Petersburg 192019, Russia
  • Wechsberg, Wendee M
    • Other Affiliation: Substance Abuse Treatment Evaluations and Interventions Research Program, RTI International, Research Triangle Park, NC 27709, USA
Abstract
  • Abstract Background This paper reports on the feasibility and initial efficacy of a culturally sensitive, comprehensive women-centered substance use intervention for women who inject drugs in Georgia in terms of the primary and secondary sex risk outcomes. The hypothesis under examination was that, relative to case management participants, participants in a culturally sensitive, comprehensive women-specific and -centered intervention would, on average, show significant decreases in past-30-day frequency of unprotected sex, unprotected sex at the last sexual encounter, and increases in condom use and safer sex actions. Methods The study was a two-arm randomized trial, in which 173 potentially eligible women were screened, and those 128 women determined to be eligible were assigned at random to either Reinforcement-based Treatment plus Women’s Co-Op (RBT + WC) or case management (CM). RBT + WC participants received 12 sessions of a structured intervention with the goal of reducing risky sex and substance use and improving physical and mental health. CM participants received 12 sessions of case management and informational brochures that focused on the same issues on which RBT + WC focused. Participants were assessed at baseline, post-treatment, and 3 months following treatment enrollment. Results Analyses revealed case management having significantly overall higher Safer Sex action scores than RBT + WC, and a significant decrease over time for past 30-day number of unprotected sex acts. Unprotected sex at the last encounter and Condom Use action scores were nonsignificant. Conclusions Women who inject drugs in Georgia are engaging in risky sexual practices, and are in need of an intervention that addresses these risky behaviors. Reasons for the failure to find differences between a culturally sensitive, comprehensive women-centered intervention and case management tailored to the needs of women who inject drugs in Georgia may have been the result of inadequate power to detect an effect in a sample whose drug use was not as serious as warranted by the intervention. (ClinicalTrials.gov Identifier: NCT01331460 )
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  • Article
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  • In Copyright
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  • Jones et al.
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  • English
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  • Substance Abuse Treatment, Prevention, and Policy. 2015 Dec 08;10(1):47
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  • BioMed Central

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