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Molecular Mechanisms of Patient-Derived KEAP1 Superbinder Mutants

Creator: Cloer, Erica

Embargoed Until: 2019-12-31

In 30% of lung cancers, mutations in KEAP1 or NRF2 result in constitutive NRF2 activity. This promotes tumor progression, resistance to radio- and chemotherapy, and predicts poor patient outcome. Over 700 somatic mutations in the KEAP1 tumor (more)

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20171130_Cloer_Dissertation_Table_S_2_1.xlsx

Date Deposited: 2018-03-15

Date Created: 2018-03-15

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20171130_Cloer_Dissertation_Table_S_2_2.xlsx

Date Deposited: 2018-03-15

Date Created: 2018-03-15

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20171130_Cloer_Dissertation_Table_S_2_3.xlsx

Date Deposited: 2018-03-15

Date Created: 2018-03-15

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20171130_Cloer_Dissertation_Table_S_3_1_NFE2L2_cBioPortal.xlsx

Date Deposited: 2018-03-15

Date Created: 2018-03-15

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20171130_Cloer_Dissertation_Table_S_3_2_KEAP1_cBioPortal.xlsx

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20171130_Cloer_Dissertation_Table_S_3_3_NFE2L2_PROMALS.xlsx

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20171130_Cloer_Dissertation_Table_S_3_4_KEAP1_PROMALS.xlsx

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Date Created: 2018-03-15

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Cloer_unc_0153D_17470.pdf

Date Deposited: 2018-03-15

Date Created: 2018-03-15

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