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A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

Creator: Lee, Hee-Sheung, Lee, Nicholas C.O., Grimes, Brenda R., Samoshkin, Alexander, Kononenko, Artem V., Bansal, Ruchi, Masumoto, Hiroshi, Earnshaw, William C., Kouprina, Natalay, Larionov, Vladimir

Abstract Background Aneuploidy is a feature of most cancer cells that is often accompanied by an elevated rate of chromosome mis-segregation termed chromosome instability (CIN). While CIN can act as a driver of cancer (more)

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1471-2407-13-252.pdf

Collection: BioMed Central

Date Deposited: 2013-06-04

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