Mycobacterium avium-intracellularecellulitis occurring with septic arthritis after joint injection: a case report

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  • Murdoch, David
    • Affiliation: Gillings School of Global Public Health
    • Other Affiliation: Division of Pulmonary & Critical Care Medicine, Box 3221, Duke University Medical Center
  • McDonald, Jay R
    • Other Affiliation: Division of Infectious Diseases, Box 3824, Duke University Medical Center
Abstract
  • Background Cellulitis caused by Mycobacterium avium-intracellulare has rarely been described. Mycobacterium avium-intracellulare is a rare cause of septic arthritis after intra-articular injection, though the causative role of injection is difficult to ascertain in such cases. Case presentation A 57-year-old with rheumatoid arthritis treated with prednisone and azathioprine developed bilateral painful degenerative shoulder arthritis. After corticosteroid injections into both acromioclavicular joints, he developed bilateral cellulitis centered over the injection sites. Skin biopsy showed non-caseating granulomas, and culture grew Mycobacterium avium-intracellulare. Joint aspiration also revealed Mycobacterium avium-intracellulare infection. Conclusion Although rare, skin and joint infections caused by Mycobacterium avium-intracellulare should be considered in any immunocompromised host, particularly after intra-articular injection. Stains for acid-fast bacilli may be negative in pathologic samples even in the presence of infection; cultures of tissue specimens should always be obtained.
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  • Article
Rights statement
  • In Copyright
Rights holder
  • David M Murdoch et al.; licensee BioMed Central Ltd.
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Journal title
  • BMC Infectious Diseases
Journal volume
  • 7
Journal issue
  • 1
Page start
  • 9
Language
  • English
Is the article or chapter peer-reviewed?
  • Yes
ISSN
  • 1471-2334
Bibliographic citation
  • BMC Infectious Diseases. 2007 Feb 26;7(1):9
Publisher
  • BioMed Central Ltd
Access right
  • Open Access
Date uploaded
  • July 15, 2016

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