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Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

Creator: Herschkowitz, Jason I, Simin, Karl, Weigman, Victor J, Mikaelian, Igor, Usary, Jerry, Hu, Zhiyuan, Rasmussen, Karen E, Jones, Laundette P, Assefnia, Shahin, Chandrasekharan, Subhashini, Backlund, Michael G, Yin, Yuzhi, Khramtsov, Andrey I, Bastein, Roy, Quackenbush, John, Glazer, Robert I, Brown, Powel H, Green, Jeffrey E, Kopelovich, Levy, Furth, Priscilla A, Palazzo, Juan P, Olopade, Olufunmilayo I, Bernard, Philip S, Churchill, Gary A, Van Dyke, Terry A., Perou, Charles

Abstract Background Although numerous mouse models of breast carcinomas have been developed, we do not know the extent to which any faithfully represent clinically significant human phenotypes. To address this need, we characterized mammary tumor (more)

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13059_2006_article_1558.pdf

Collection: BioMed Central

Date Deposited: 2016-01-22

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Additional file 2: Complete unsupervised cluster diagram of all mouse tumors

Collection: BioMed Central

Date Deposited: 2018-03-22

Date Created: 2018-03-22

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Additional file 4: CC analyses applied to the mouse models

Collection: BioMed Central

Date Deposited: 2016-01-22

Date Created: 2016-01-22

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Additional file 8: GSEA of murine pathway models versus five human subtypes

Collection: BioMed Central

Date Deposited: 2016-01-22

Date Created: 2016-01-22

doc  (49 KB)