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CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo

Creator: Tsao, Li-Chung, Guo, Haitao, Jeffrey, Jerry, Hoxie, James A, Su, Lishan

Abstract Background CD4 T cell depletion during HIV-1 infection is associated with AIDS disease progression, and the HIV-1 Env protein plays an important role in the process. Together with CXCR4, CCR5 is one of the two co-receptors that interact with (more)

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12977_2016_article_255.pdf

Collection: BioMed Central

Date Deposited: 2016-04-02

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Additional file 1: Figure S1. CXCR4 antagonist AMD3100 inhibits R3A replication

Collection: BioMed Central

Date Deposited: 2016-04-02

Date Created: 2016-04-02

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Additional file 2: Figure S2. Similar infection levels by R3A and R3A- 5/6AA in PBMCs

Collection: BioMed Central

Date Deposited: 2016-04-02

Date Created: 2016-04-02

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