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Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury

Creator: Usachov, Valentyn, Urban, Thomas J, Fontana, Robert J, Gross, Annika, Iyer, Sapna, Omary, M. B, Strnad, Pavel

Abstract Background Keratin 8 and 18 (K8/K18) cytoskeletal proteins protect hepatocytes from undergoing apoptosis and their mutations predispose to adverse outcomes in acute liver failure (ALF). All known K8/K18 variants occur at relatively non- (more)

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12916_2015_article_418.pdf

Collection: BioMed Central

Date Deposited: 2016-10-07

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Additional file 1: Figure S1

Collection: BioMed Central

Date Deposited: 2016-10-07

Date Created: 2016-10-07

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Additional file 3: Figure S2. Conservation of the novel K8 variants...

Collection: BioMed Central

Date Deposited: 2016-10-07

Date Created: 2016-10-07

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