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Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures

Creator: Kornegay, Joe N., Bogan, Daniel J, Bogan, Janet R, Dow, Jennifer L, Wang, Jiahui, Fan, Zheng, Liu, Naili, Warsing, Leigh C, Grange, Robert W, Ahn, Mihye, Balog-Alvarez, Cynthia J, Cotten, Steven W, Willis, Monte, Brinkmeyer-Langford, Candice, Zhu, Hongtu, Palandra, Joe, Morris, Carl A, Styner, Martin, Wagner, Kathryn R

Abstract Background Myostatin (Mstn) is a negative regulator of muscle growth whose inhibition promotes muscle growth and regeneration. Dystrophin-deficient mdx mice in which myostatin is knocked out or inhibited postnatally have a less severe (more)

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13395_2016_article_85.pdf

Collection: BioMed Central

Date Deposited: 2016-04-08

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